A5083760961- SARS-CoV-2 and COVID-19 Research
- Plant nutrient uptake and metabolism
- Bacterial Identification and Susceptibility Testing
- Pleural and Pulmonary Diseases
- Urologic and reproductive health conditions
- Mosquito-borne diseases and control
- Food Industry and Aquatic Biology
- Horticultural and Viticultural Research
- Plant Stress Responses and Tolerance
- Occupational and environmental lung diseases
- Viral gastroenteritis research and epidemiology
- Plant responses to water stress
- Clostridium difficile and Clostridium perfringens research
- Urological Disorders and Treatments
- Viral Infections and Immunology Research
- Antimicrobial Resistance in Staphylococcus
- Viral Infections and Vectors
- Veterinary Medicine and Surgery
- Plant Physiology and Cultivation Studies
Hokkaido University
2021-2025
Tokyo Medical and Dental University Hospital
2019
Nagoya University
2017
Medical treatments using potent neutralizing SARS-CoV-2 antibodies have achieved remarkable improvements in clinical symptoms, changing the situation for severity of COVID-19 patients. We previously reported an antibody, NT-108 with activity. However, structural and functional basis activity has not yet been understood. Here, we demonstrated therapeutic effects a hamster model its protective at low doses. Furthermore, determined cryo-EM structure complex spike. The single-chain Fv...
Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infections are causing significant morbidity and mortality worldwide. Furthermore, over 1 million cases of newly emerging or re-emerging viral infections, specifically dengue virus (DENV), known to occur annually. Because no virus-specific fully effective treatments against these many other viruses have been approved, there is an urgent need for novel, therapeutic agents. Here, we identified 2-thiouridine (s2U) as a broad-spectrum...
Clostridioides difficile ribotype (RT) 019/sequence type (ST) 67 strains belong to a hypervirulent lineage closely related RT027/ST1; however, limited data are available for clade 2 lineages in Japan. Herein, we report the draft genome of C. strain B18-123 belonging 2, RT019/ST67 first time The pathogenicity locus carried by (19.6 kb) showed higher homology (97.29% nucleotide identity) with R20291 (RT027/ST1) than reference 630 (RT012/ST54), and harbored 8-nucleotide substitutions tcdC....
A 12-year-old castrated male Shih Tzu presented to the hospital with hematuria that had lasted for about 1 month. Abdominal ultrasonography and computed tomography revealed hydronephrosis due a mass in left urinary tract adrenal tumor. Adrenal glandectomy nephroureterectomy were performed. The histopathological examination concurrent adrenocortical adenoma pheochromocytoma same gland. fibroepithelial polyp developed ureter, subsequent hydronephrosis. There was no recurrence or metastasis of...
Abstract Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection causes significant morbidity and mortality worldwide, seriously impacting not only human health but also the global economy. Furthermore, over 1 million cases of newly emerging or re-emerging viral infections, specifically dengue virus (DENV), are known to occur annually. Because no virus-specific fully effective treatments against these many other viruses have been approved, they continue be responsible for...