- Alzheimer's disease research and treatments
- Gastrointestinal motility and disorders
- GABA and Rice Research
- Genetics and Plant Breeding
- Obesity, Physical Activity, Diet
- Diet and metabolism studies
- Nutritional Studies and Diet
- Eating Disorders and Behaviors
- Agronomic Practices and Intercropping Systems
- Complementary and Alternative Medicine Studies
- Fibromyalgia and Chronic Fatigue Syndrome Research
- Consumer Attitudes and Food Labeling
- Soybean genetics and cultivation
- Neurological Disease Mechanisms and Treatments
- Dermatology and Skin Diseases
- Plant Reproductive Biology
- Pharmacological Effects of Natural Compounds
- Phytochemical and Pharmacological Studies
- Growth and nutrition in plants
- Biochemical Analysis and Sensing Techniques
- Cardiovascular Health and Disease Prevention
- Bee Products Chemical Analysis
- Probiotics and Fermented Foods
- Biochemical effects in animals
- Gut microbiota and health
Hokkaido Information University
2013-2024
Bio-oriented Technology Research Advancement Institution
2024
Gamma-aminobutyric acid (GABA) is an inhibitory neurotransmitter with beneficial effects including antihypertension and antistress properties. In this study, we examined the of GABA-enriched white rice (GABA rice) on blood pressure (BP) in 39 mildly hypertensive adults a randomized, double-blind, placebo-controlled study. The participants were divided into test group (n = 22) who consumed 11.2 mg GABA/100 g placebo 17) 2.7 rice. For 8 weeks, took 150 either GABA or Hematological examinations...
Quercetin, a type of flavonoid, is believed to reduce age-related cognitive decline. To elucidate its potential function, we carried out randomized, double-blind, placebo-controlled, parallel-group comparative clinical trial involving 24-week continuous intake quercetin-rich onion compared quercetin-free as placebo. Seventy healthy Japanese individuals (aged 60 79 years old) were enrolled in this study. We examined the effect (the active test food) on function using Mini-Mental State...
Human gut health is closely related to sleep. We aimed evaluate the efficacy of yeast mannan (YM) in improving bowel habits and sleep quality, along with metabolomics fecal samples. A total 40 healthy adults (age range, 22–64 years) discomfort defecation were enrolled randomly allocated receive either YM (n = 20; 1.1 g/day) or placebo 20) for four weeks. Participants recorded their throughout test periods. Sleep electroencephalogram (EEG) recording using an EEG device sampling performed pre-...
Presenteeism is a problem that needs to be solved urgently, both for individual workers and society overall. In this report, we propose the concept of MHC, which refers mild mental physical complaints subjectively perceived by individuals are not caused illness. We also planned examine what kind disorder MHC whether food effective as method self-care MHC. First, conducted "the comprehensive survey establish an integrated database food, gut microbiome, health information" (the "Sukoyaka...
Adlay has been used as a traditional Chinese medicine and nutrient for its beneficial effects on bowel movements skin care. This study examined the effect of enzymatic degradation product adlay, "Super Hatomugi" (SPH) human intestinal flora in randomized, double-blind placebo-controlled study. The subjects were divided into three groups: 500 mg SPH, 1000 placebo, taken daily 4 weeks. Hematological condition examinations well an analysis performed 2 weeks before 10 after start SPH intake....
Measurement of amyloid concentration in blood using time-of-flight mass spectrometry was developed, and the combined normalized score precursor proteins (composite biomarker: CM) plasma found to be related accumulation β-amyloid (Aβ) brain.Therefore, we measured CM value healthy subjects aged 30-79 years investigated association between clinical characteristics multiple regression decision tree analyses.The results indicated that associated with age, sex, ApoE genotype, glucose, Mg...
Abstract Diet has been repeatedly shown to affect mental and sleep health outcomes. However, it is well known that there are cross‐cultural differences in dietary practices as the prevalence of Given inflammatory potential diets linked outcomes, current study we sought assess status habitual examine its relationship with outcomes both United Kingdom Japan. Our aim was determine if associations between inflammation index (DII) score these could elucidate any health. Online survey data...
Heyndrickxia coagulans SANK70258, a representative probiotic, is known for alleviating inflammation caused by cedar pollen, improving the intestinal environment and bowel movements. A previous study on consuming H. SANK70258 together with galactooligosaccharides showed trend toward improvement in skin scaliness scores subjective assessments of roughness. However, effect alone remains unclear. Thus, we aimed to re-evaluate effects intake conditions through clinical trial.
Asparagus ( Lú Sǔn; officinalis L.) is a common vegetable, long used as an herbal medicine. The cladophylls and bottom-stems of asparagus have various pharmacological effects, but they are generally discarded at harvesting. present open clinical trial was performed to examine the effects intake on improvement metabolic syndrome characterized by hypertension, hyperglycemia, dyslipidemia. Twenty-eight healthy volunteers ingested either cladophyll or bottom-stem powder (6 g/day) daily for 10...
The purple-flesh potato (Solanum tuberosum L.) cultivar "Shadow Queen" (SQ) naturally contains anthocyanins. This randomized, double-blind, placebo-controlled study determines whether ingesting purple potatoes increases the number of mesenchymal stem cells (MSC) and improves stress response, a minor health complaint in healthy adults (registration number: UMIN000038876). A total 15 subjects (ages: 50-70 years) with complaints were randomly assigned to one two groups. For 8 weeks, placebo...
In Japan, many workers are exposed to chronic stress, sleep deprivation, and nutritional imbalance. They tend still go work when ill, leading decreased performance productivity, which has become a major social problem. We conducted human entry study with the aim of finding link between these two factors proposing an optimized diet, believing that review diet may lead improvement in labor productivity. this study, we used subjective accomplishment (SA) as measure First, compared nutrient...
Japanese dietary patterns have traditionally focused on vegetables, legumes, and fish; however, in the last few quarters of century, consumption meat, processed food, ultra-processed food has become popular. It is anticipated that these changes environment will increase risk developing psychosomatic disorders.
<title>Abstract</title> Cytoplasmic male sterility (CMS) is used in breeding to facilitate hybrid seed production. <italic>Restorer of fertility</italic> (<italic>Rf</italic>), the suppressor CMS, consists a gene cluster with multiple haplotypes. Selection restoring or non-restoring alleles depends on discrimination <italic>Rf</italic> haplotypes using DNA markers. The efficacy this system decreased if haplotype differs within population interest, which can occur during crop evolution. In...
Abstract Accumulation of β-amyloid (Aβ) in the brain occurs early phase Alzheimer’s disease (AD), without symptoms cognitive decline. Therefore, detection accumulation is essential to prevent or delay AD. In this study, we investigated effects age, sex, apoprotein-E (ApoE) genotype and dysfunction on ratio Aβ 1-42 , 1-40 amyloid β precursor protein (APP) 669-711 (composite biomarker: CM) plasma using a sensitive Time flight mass spectrometry (TOF-MS). healthy subjects, average CM value males...
Background: Kumaizasa (Sasa. senanensis (Franchet et Savatier) Rehder) is a bush-type bamboo grown in Hokkaido, Japan and has traditionally been used as material for herbal medicine health food. The purpose of this study was to investigate the effect daily ingestion powder (4.2g/day) 2 weeks improvement constipation. We conducted placebo-controlled, randomized, double-blind, parallel-group comparison on 80 healthy Japanese men women between ages 20 65 who complained chronic Results: stool...