- Global Maternal and Child Health
- Child Nutrition and Water Access
- Aquatic Ecosystems and Biodiversity
- HIV/AIDS Research and Interventions
- Malaria Research and Control
- Mosquito-borne diseases and control
- HIV Research and Treatment
- Adolescent Sexual and Reproductive Health
- Vaccine Coverage and Hesitancy
- ICT in Developing Communities
- Diagnosis and treatment of tuberculosis
- Tuberculosis Research and Epidemiology
- COVID-19 epidemiological studies
- Travel-related health issues
- Pneumocystis jirovecii pneumonia detection and treatment
- Retinal Imaging and Analysis
- Healthcare Systems and Reforms
- Census and Population Estimation
- Immune responses and vaccinations
- Primary Care and Health Outcomes
- Colorectal Cancer Screening and Detection
- Migration, Health and Trauma
- Acute Ischemic Stroke Management
- COVID-19 diagnosis using AI
- Demographic Trends and Gender Preferences
Makerere University
2017-2024
Centers for Disease Control and Prevention
2023-2024
Ministry of Health
2023
Swiss Tropical and Public Health Institute
2017-2020
University of Basel
2017-2020
Mulago Hospital
2010-2020
Uganda Virus Research Institute
2014-2018
Malaria burden in Uganda has declined disproportionately among regions despite overall high intervention coverage across all regions. The Indicator Survey (MIS) 2014-15 was the second nationally representative survey conducted to provide estimates of malaria prevalence children less than 5 years, and track progress control interventions country. In this present study, MIS data were analysed assess effects on at regional level, estimate geographical distribution country.Bayesian...
Although malaria burden in Uganda has declined since 2009 following the scale-up of interventions, disease is still leading cause hospitalization and death. Transmission remains high driven by suitable weather conditions. There a real concern that intervention gains may be reversed climatic changes country. In this study, we investigate effects climate on spatio-temporal trends incidence during 2013-2017.Bayesian negative binomial models were fitted district-aggregated monthly cases,...
Although the association between alcohol consumption and HIV risk is well documented, few studies have examined magnitude of new infections that could be prevented by controlling use. We report population attributable fraction (PAF) incident due to among high-risk fishing communities along Lake Victoria, Uganda.In a community-based cohort study, 1607 sero-negative participants aged 18-49 years were enrolled from eight Uganda. At follow up 12 months later, 1288 (80.1%) seen interviewed....
In Uganda, malaria vector control interventions and case management with Artemisinin Combination Therapies (ACTs) have been scaled up over the last few years as a result of increased funding. Data on parasitaemia prevalence among children less than 5 old coverage was collected during first two Malaria Indicator Surveys (MIS) conducted in 2009 2014, respectively. this study, we quantify effects risk changes between MIS spatio-temporal analysis. Bayesian geostatistical temporal models were...
An effective HIV vaccine is still elusive. Of the 9 preventive efficacy trials conducted to-date, only one reported positive results of modest efficacy. More need to be before or more vaccines are eventually licensed. We assessed suitability fishing communities in Uganda for future trials.A community-based cohort study was among a random sample 2191 participants aged 18-49 years. Data were collected on socio-demographic characteristics, risky behaviors, and willingness participate (WTP)....
There is paucity of evidence for the role health service delivery to malaria decline in Uganda We developed a methodology quantify facility readiness and assessed its on severe outcomes among lower-level facilities (HCIIIs HCIIs) country. Malaria data was extracted from Health Management Information System (HMIS). General malaria-specific indicators were obtained 2013 indicator survey. Multiple correspondence analysis (MCA) used construct composite score based multiple factorial axes....
During October 2016-March 2022, Uganda increased tuberculosis (TB) preventive therapy coverage among persons living with HIV from 0.6% to 88.8%. TB notification rates 881.1 972.5 per 100,000 HIV. Timely screening, diagnosis, and earlier treatment should remain high priorities for TB/HIV prevention programming.
Electronic reporting of routine health facility data in Uganda began with the adoption District Health Information Software System version 2 (DHIS2) 2011. This has improved and overall quality. In this study, effects case management artemisinin-based combination therapy (ACT) vector control interventions on space–time patterns disease incidence were determined using DHIS2 reported during 2013–2016. Bayesian spatio-temporal negative binomial models fitted district-aggregated monthly malaria...
Uganda´s fishing communities experience a high burden of sexually transmitted infections (STIs) including human immunodeficiency virus (HIV), with limited access to healthcare. Knowledge on healthcare use and treatment seeking will help identify unmet needs facilitate appropriate allocation resources.
Introduction Fishing communities (FCs) in Uganda have high HIV infection rates but poor access to health services including family planning (FP). Although FP is a cost-effective public intervention, there paucity of data on knowledge and use modern FCs. This study determined methods FCs Uganda. Methods Data were accrued from 12-month follow up 1,688 HIV-uninfected individuals, 18–49 years 8 along Lake Victoria, between September 2011 March 2013. collected through semi-structured...
Information on the causes of death among under-five children is key in designing and implementation appropriate interventions. In Uganda, civil registration incomplete which limits estimation disease-related mortality burden especially at a local scale. absence routine cause-specific data, we used household surveys to quantify effects contribution main childhood diseases such as malaria, severe or moderate anaemia, malnutrition, diarrhoea acute respiratory infections (ARIs) all-cause (U5M)...
High retention (follow-up) rates improve the validity and statistical power of outcomes in longitudinal studies effectiveness programs with prolonged administration interventions. We assessed participant a potential HIV vaccine trials population fishing communities along Lake Victoria, Uganda. In community-based individual randomized trial, 662 participants aged 15–49 years were to either mobile phone or physical contact tracing reminders followed up at months 1, 2, 3, 6, 12 18...
Objectives: To explore whether community health worker household-based maternal visits improve antenatal care and skilled birth attendance among hard-to-reach fishing villages on Lake Victoria, Uganda. Methods: This quasi-experimental 18-month prospective study involved 486 consenting women aged 15–49 years, who were pregnant or had a pregnancy outcome in the past 6 months, from island communities. The intervention (community workers’ household to provide counseling, blood pressure...
Uganda is among the most HIV/AIDS-afflicted countries, and many HIV-infected persons live in remote areas with poor access to health care. The success of HIV care programs relies part on patient monitoring using CD4 T cell counts. We conducted an evaluation point-of-care PIMA test BD FACSCount as a gold standard. One hundred fifty-one participants were enrolled, provided venous blood samples tested at point Alere PIMA™ Analyzer UVRI-IAVI main laboratory. Correlation between methods was...
To reduce the under-five mortality (U5M), fine-gained spatial assessment of effects health interventions is critical because national averages can obscure important sub-national disparities. In turn, estimates guide control programmes for targeting. The purpose our study to quantify associations with U5M rate at and scales in Uganda identify associated largest reductions scale.Spatially explicit data on U5M, sociodemographic indicators were obtained from 2011 Demographic Health Survey (DHS)....
<sec> <title>BACKGROUND</title> Labeling color fundus photos (CFP) is an important step in the development of artificial intelligence screening algorithms for detection diabetic retinopathy (DR). Most studies use International Classification Diabetic Retinopathy (ICDR) to assign labels CFP, plus presence or absence macular edema (ME). Images can be grouped as referrable nonreferrable according these classifications. There little guidance literature about how collect and metadata a part CFP...
Background Labeling color fundus photos (CFP) is an important step in the development of artificial intelligence screening algorithms for detection diabetic retinopathy (DR). Most studies use International Classification Diabetic Retinopathy (ICDR) to assign labels CFP, plus presence or absence macular edema (ME). Images can be grouped as referrable nonreferrable according these classifications. There little guidance literature about how collect and metadata a part CFP labeling process....
Seasonal malaria chemoprevention (SMC) refers to monthly administration of full treatment courses anti-malarial medicine children <5 years during high transmission seasons. SMC has demonstrated effectiveness in Sahel and sub-Sahel countries Africa. However, it was not implemented Uganda until April 2021, when the country began highly malaria-endemic Kotido Moroto Districts. This study assessed effect on incidence among age An interrupted time-series analysis conducted using national health...
Background In 2019, WHO recommended dolutegravir (DTG) as a backbone for first- and second-line antiretroviral therapy (ART) regimens people living with HIV (PLHIV). According to the 2018 Uganda’s treatment guidelines, patients viral non-suppression (≥1,000 copies/mL) should receive intensive adherence counseling (IAC) repeat load (VL) within 6 months. This analysis focused on prevalence factors associated suppression following IAC among PLHIV DTG-based (DBRs) an initial episode of (VNS) in...
Background Despite massive investment in diseases responsible for fever among children less than five years Uganda, the burden of symptom remains high and disproportionately distributed across regions. In studies assessing relationship between prevalence multiple childhood diseases, especially at a local scale are scanty. We analyse 2016 Demographic Health Survey (DHS) data to quantify associations contribution Uganda national regional level. Findings can lead development implementation...
Abstract Background Maternal mortality is still a challenge in Uganda, at 336 deaths per 100,000 live births, especially rural hard to reach communities. Distance health facility influences maternal deaths. We explored women’s mobility for health, distances travelled antenatal care (ANC) and childbirth among hard-to-reach Lake Victoria islands fishing communities (FCs) of Kalangala district, Uganda. Methods A cross sectional survey 450 consenting women aged 15–49 years, with prior was...