A5085675262- COVID-19 epidemiological studies
- Viral Infections and Outbreaks Research
- Mosquito-borne diseases and control
- Malaria Research and Control
- Viral Infections and Vectors
- Child Nutrition and Water Access
- Data-Driven Disease Surveillance
- Blood Pressure and Hypertension Studies
- Insect Pest Control Strategies
- Vaccine Coverage and Hesitancy
- HIV Research and Treatment
- Coastal and Marine Management
- HIV/AIDS Research and Interventions
- Viral gastroenteritis research and epidemiology
- Virology and Viral Diseases
- ICT in Developing Communities
- Disaster Response and Management
- Emergency and Acute Care Studies
- Diverse Scientific Research Studies
- Cardiovascular Health and Risk Factors
- Zoonotic diseases and public health
- Sodium Intake and Health
- Clostridium difficile and Clostridium perfringens research
- SARS-CoV-2 and COVID-19 Research
- Pneumocystis jirovecii pneumonia detection and treatment
Makerere University
2022-2025
Infectious Diseases Institute
2024-2025
Ministry of Health
2024
In October 2022, the Uganda Ministry of Health (MoH) confirmed first case a Sudan Virus Disease (SVD) outbreak in Kampala Metropolitan area (KMA). A multicomponent infection prevention and control (IPC) strategy was implemented to spread Orthoebolavirus sudanense (SUDV) KMA. We describe deployment this strategy, its effect on IPC capacities, successful SVD KMA during 2022 outbreak. The included (1) pillar coordination: an task force convened by government health partner representatives...
COVID-19 vaccination was launched in March 2021 Uganda and initially prioritized persons >50 years of age, with underlying conditions, healthcare workers, teachers, security forces. However, uptake remained low 5 months after the program launch. Makerere University's Infectious Diseases Institute supported Uganda's Ministry Health optimizing models by using point-of-care, place worship, work engagement Social Assistance Grant for Empowerment model 47 135 districts Uganda, where we trained...
BackgroundEarly isolation and care for Ebola Disease patients at Treatment Units (ETU) curb outbreak spread. We evaluated time to ETU entry associated factors during the 2022 Sudan virus disease (SVD) in Uganda.MethodsWe included persons with RT-PCR-confirmed SVD onset September 20–November 30, 2022. categorized days from symptom ('delays') as short (≤2), moderate (3-5), long (≥6); latter two were 'delayed isolation'. timing 'earlier' or 'later,' using October 15 a cut-off. assessed...
Abstract Background The COVID-19 pandemic overwhelmed the capacity of health facilities globally, emphasizing need for readiness to respond rapid increases in cases. first wave Uganda peaked late 2020 and demonstrated challenges with facility manage second began May 2021. In June 2021, we assessed COVID-19. Methods Referral hospitals managed severe patients, while lower-level screened, isolated, mild We 17 20 referral 71 3,107 facilities, selected using multistage sampling. interviewed heads...
Abstract Background On 20 September 2022, Uganda declared its fifth Sudan virus disease (SVD) outbreak, culminating in 142 confirmed and 22 probable cases. The reproductive rate (R) of this outbreak was 1.25. We described persons who were exposed to the virus, became infected, they led infection an unusually high number cases during outbreak. Methods In descriptive cross-sectional study, we defined a super-spreader person (SSP) as any with real-time polymerase chain reaction (RT-PCR) SVD...
Uganda conducted its third mass long-lasting insecticidal net (LLIN) distribution campaign in 2021. The target of the was to ensure that 100% households own at least one LLIN per two persons and achieve 85% use distributed LLINs. ownership, associated factors were assessed 3 months after campaign.A cross-sectional household survey 14 districts from 13 30 April, Households selected using multistage sampling. Each asked about use, duration since received time interview, presence LLINs visually...
Diarrheal diseases, are major concerns for Ugandan children; persistent in Obongi District despite high rotavirus vaccination rates (2019-2021). The district recorded the country's highest annual acute watery diarrhea (AWD) incidence from 2017 to 2021. Our study, conducted April 2022, assessed AWD risk factors among 0-59-month-old children Obongi. We a 1:2 (193:386) unmatched case-control study. A case was child (0-59 months) with ≥ 3 loose/liquid stools/day, negative malaria/pneumonia...
<sec> <title>BACKGROUND</title> In 2017, Uganda implemented an electronic Integrated Disease Surveillance and Response System (eIDSR) to improve data completeness reporting timelines. However, the eIDSR system had limited functionality was on a small scale. The Ministry of Health (MOH), with support from Infectious Institute (IDI) Information Systems Program (HISP-Uganda), upgraded scaled up its implementation. </sec> <title>OBJECTIVE</title> We describe upgrade system, rollout, effect...
Abstract Background Uganda Ministry of Health (MOH) recommends a first HIV DNA-PCR test at 4–6 weeks for early infant diagnosis (EID) HIV-exposed infants (HEI) and immediate return results. WHO initiating antiretroviral therapy (ART) ≤ 7 days from diagnosis. In 2019, MOH introduced point-of-care (POC) whole-blood EID testing in 33 health facilities scaled up to 130 2020. We assessed results turnaround time ART linkage pre-POC during POC testing. Methods evaluated register data HEI 10 with...
Abstract Background Individuals living in communities with poor access to healthcare may be unaware of their high blood pressure (BP). While the use community health workers (CHWs) can address gaps human resources for health, CHWs Uganda have not been used previously BP screening and management. We report results an initiative train evaluate administer group-based education Kalangala Buvuma Island Districts Lake Victoria, Uganda. Methods randomly selected 42 212 villages. trained based...
Background: The Uganda Ministry of Health (MoH) and implementing partners instituted an infection prevention control (IPC) response strategy during the SVD outbreak in 2022 that involved rapid enhancement screening capacity at HCFs. Rapid scale-up for infectious diseases, such as SVD, is critical early identification triage suspected or confirmed cases We describe deployment a multimodal IPC implemented to resulting impact on measures Methods: HCFs from five high risk districts improve...
In 2017, Uganda implemented an electronic Integrated Disease Surveillance and Response System (eIDSR) to improve data completeness reporting timelines. However, the eIDSR system had limited functionality was on a small scale. The Ministry of Health, with support from Infectious Institute, Makerere University, Health Information Systems Program Uganda, upgraded scaled up its implementation. This study describes process impact upgrading expanding implementation across additional districts....
Seasonal malaria chemoprevention (SMC) refers to monthly administration of full treatment courses anti-malarial medicine children <5 years during high transmission seasons. SMC has demonstrated effectiveness in Sahel and sub-Sahel countries Africa. However, it was not implemented Uganda until April 2021, when the country began highly malaria-endemic Kotido Moroto Districts. This study assessed effect on incidence among age An interrupted time-series analysis conducted using national health...
Abstract Background: Individuals living in communities with poor access to healthcare may be unaware of their high blood pressure (BP). While the use community health workers (CHWs) can address gaps human resources for health, CHWs Uganda have not been used previously BP screening and management. We report results an initiative train evaluate administer group-based education Kalangala Buvuma Island Districts Lake Victoria, Uganda. Methods: randomly selected 42 212 villages. trained 84 based...
Background: Diarrheal diseases, are major concerns for Ugandan children, persisted in Obongi District despite high rotavirus vaccination rates (2019-2021). The district recorded the country's highest annual acute watery diarrhea (AWD) incidence from 2017-2021. Our study, conducted April 2022, assessed AWD risk factors among 0-59-month-old children Obongi.Methods: We a 1:2 (193:386) unmatched case‒control study. A case was child (0-59 months) with ≥3 loose/liquid stools/day, negative...
Abstract Background: On September 20, 2023, Uganda declared its 5 th Sudan virus disease (SVD) outbreak, culminating in 142 confirmed and 22 probable cases. The reproductive rate (R) of this outbreak was 1.25. We describe persons to whom exposure resulted an unusual number cases during the outbreak. Methods: defined a super-spreader person (SSP) as any with RT-PCR-confirmed SVD linked infection ≥13 other (10-fold R). reviewed illness narratives for SSPs collected through interviews....
Background: Early isolation and appropriate care for Ebola Disease patients at Treatment Units (ETU) curb outbreak spread reduce deaths. We evaluated time to ETU entry associated factors during the 2022 Sudan virus disease (SVD) in Uganda.Methods: included persons with RT-PCR-confirmed SVD onset after was declared September 20–November 30, 2022. categorized days from symptom (‘delays’) as short (≤2), moderate (3-5), long (≥6); latter two were ‘delayed isolation’. timing of ‘earlier’ or...
Abstract Background An essential means to control malaria is diagnosing suspected patients with a confirmatory test, treatment of confirmed cases, and proper case registration (track). In 2011, the Ministry Health launched country-wide Test, Treat Track policy. We assessed implementation policy in Gulu district, Uganda. Methods This was cross sectional study conducted 8 health facilities district. abstracted data from out-patient laboratory register January 2019 December, 2019. used...
Abstract Background: Uganda conducted its third mass Long-Lasting Insecticide-treated Net ( LLIN) distribution campaign in 2021. The target of the was to ensure that 100% households own at least 1 LLIN per 2 persons and achieve 85% use distributed LLINs. We assessed ownership, use, associated factors 3 months after campaign. Methods: a cross-sectional household survey 14 districts during April 13-30, selected using multistage sampling. asked about duration since received until time...