A5101061292- MicroRNA in disease regulation
- Advanced Photocatalysis Techniques
- Ga2O3 and related materials
- Atherosclerosis and Cardiovascular Diseases
- ZnO doping and properties
- Inflammatory mediators and NSAID effects
- interferon and immune responses
- Nonlinear Optical Materials Studies
- Extracellular vesicles in disease
- Phase-change materials and chalcogenides
- Polyoxometalates: Synthesis and Applications
- Perovskite Materials and Applications
- Hippo pathway signaling and YAP/TAZ
- Plasmonic and Surface Plasmon Research
- Chalcogenide Semiconductor Thin Films
- Advanced Antenna and Metasurface Technologies
- Advanced Nanomaterials in Catalysis
- Coral and Marine Ecosystems Studies
- Metamaterials and Metasurfaces Applications
- Circular RNAs in diseases
- Eicosanoids and Hypertension Pharmacology
- NF-κB Signaling Pathways
- Wastewater Treatment and Nitrogen Removal
- Cell Adhesion Molecules Research
- Metal-Organic Frameworks: Synthesis and Applications
Zhejiang University
2024-2025
Zhejiang Lab
2024-2025
Second Affiliated Hospital of Zhejiang University
2024-2025
Nanjing University of Posts and Telecommunications
2023-2024
Jilin University
2014-2022
Union Hospital
2019-2022
Union Hospital
2014-2020
Health Commission of Jilin Province
2019
Jilin Province Science and Technology Department
2018
Changchun Institute of Technology
2018
Patients with colorectal cancer (CRC) harboring BRAF mutation have a poor prognosis. The median survival time for patients advanced BRAFV600E-mutant CRC is only approximately one year. Owing to the insensitivity standard chemotherapy, there are still no effective and highly specific treatment strategies available in clinical practice mutation. Therefore, targeting BRAFV600E site, researching exploring novel targeted therapies essential improve rate of this subtype. This study aims develop...
Sensory innervation triggers the regenerative response after injury. However, dysfunction and impairment of sensory nerves, accompanied by excessive inflammation impede tissue regeneration. Consequently, specific induction to mediate immunoregulation becomes a promising therapeutic approach. Herein, we developed cell/drug-free strategy selectively boost endogenous harness immune responses for promoting rehabilitation. Specifically, dual-functional phage was constructed with nerve–homing...
Abstract The optical chirality of metamaterials gives birth to distinct responses left circularly polarized (LCP) and right (RCP) light, leading asymmetric transmission circular dichroism (CD) light. In this work, meta-atom structure composed square semicircular combinations were designed, which exhibits extreme high ratio transmission, reflection CD values in blue light range. compare other reported structures, the can achieve better transmission. At wavelength 460 nm, incident LCP be...
The injury and apoptotic cell death of endothelial cells hallmark the development atherosclerosis (AS), characterized by dysregulation lipid homeostasis, immune responses, formation coronary plaques. However, mechanisms underlying initiation apoptosis remain ill-defined. Recent evidence suggests a role microRNAs in processes AS-associated apoptosis. Thus, we studied this question current study.AS was developed ApoE (-/-) mice suppled with high-fat diet (HFD), compared to normal (ND). Mouse...
MicroRNAs (miRNAs) play an essential role in the tumorigenesis of osteosarcoma (OS). However, effects miR-1248 on chemo-resistant potential OS have not been studied. Here, we addressed this question.The levels and apoptotic protein angiotensin II type 1 receptor (AGTR1) specimens were examined by RT-qPCR Western blotting, respectively. The relationship between AGTR1 was determined analysis Spearman's Rank Correlation Coefficients. patient survival with Kaplan-Meier curves. Bioinformatics...
In the past several years, phase change materials (PCMs) have been widely applied in energy-saving non-volatile photonic devices, such as active perfect absorbers, nanopixel displays and all-photonic memories.
Vestigial-like 4 (VGLL4) has been found to have multiple functions in tumor development; however, its role cardiovascular disease is unknown. The aim of this study was investigate the effect VGLL4 on dysfunction and inflammatory response Ox-LDL-induced human umbilical vein endothelial cells (HUVECs) mechanism, so as provide a new theoretical basis for diagnosis treatment atherosclerosis. In present study, protective activity inhibiting apoptosis, oxidative stress, inflammation, injury well...
This article proposes a new, to the best of our knowledge, separate absorption and multiplication (SAM) APD based on GaN/β-Ga2O3 heterojunction with high gains. The proposed achieved gain 1.93 × 104. We further optimized electric field distribution by simulating different doping concentrations thicknesses transition region, resulting in higher avalanche device. Furthermore, we designed instead single Ga2O3 homogeneous layer as region. Owing hole ionization coefficient, device offers up 120%...
Abstract Heat shock protein 47 (HSP47) plays an essential role in correcting folding, and abnormal folding is closely related to tumorigenesis. However, the relationship between HSP47 cancer immune response poorly studied. Herein, was found be frequently overexpressed human osteosarcomas. In animal models, inhibition resulted enhanced cell infiltration function. Transcriptome data revealed that negatively regulated CD155, a ligand of TIGIT. Immune checkpoint blockade therapy targeting novel...
This study investigated the effect of MLSS on simultaneous nitrification and denitrification in a sequencing batch reactor treating domestic wastewater. The average removal efficiencies COD TN increased from 93 68.21% to 97 74.20% with increase 3.5-4.0 7.5-8.0 g/L, respectively. However, efficiency decreased 39.45% when 9.5-10.0 g/L. Simultaneous (SND) was carried out high (7.5-8.0 g/L), SND were 43.4-52.0% 72.1-80.7%, Batch tests suggested that there strong potential apply for wastewater...
Unfavorable electron recombination, which hinders the efficiency of dye-sensitized solar cells (DSSCs), usually occurs at TiO2/dye/electrolyte interface on a photoanode. Polyoxometalates (POMs), as good acceptors, can be used electron-transfer materials in DSSCs to improve transport TiO2 and reduce recombining In this paper, pure inorganic sandwich-type POM Na9[Na3(H2O)6Cu3(H2O)3(SbW9O33)2]·40H2O (Cu3Na3POM) was mixed with form nanocomposites by simple sol-gel method. X-ray photoelectron...
AbstractTwo sandwich-type polyoxometalates (POM) based on [α-SeW9O33]8− building blocks, K8[{MnII(H2O)}2(WO)(SeW9O33)2]·12H2O (1) and K6[{MnIII(H2O)}2(WO)(SeW9O33)2]·18H2O (2), have been synthesized characterized by elemental analyses, IR, diffuse reflectance UV–vis-NIR spectra, TG, X-ray photoelectron spectroscopy, single-crystal diffraction. Electrochemical properties photocatalytic activities also investigated. Single-crystal diffraction analysis shows that the polyoxoanions of 1 2...