A5007469024- Retinal Diseases and Treatments
- Retinal Imaging and Analysis
- Retinal and Optic Conditions
- Retinal Development and Disorders
- Tuberculosis Research and Epidemiology
- Synthesis and biological activity
- Cardiac, Anesthesia and Surgical Outcomes
- Intraocular Surgery and Lenses
- Constructed Wetlands for Wastewater Treatment
- Viral Infections and Immunology Research
- Acute Ischemic Stroke Management
- Appendicitis Diagnosis and Management
- Synthesis and Characterization of Heterocyclic Compounds
- Fibroblast Growth Factor Research
- Pneumonia and Respiratory Infections
- Viral gastroenteritis research and epidemiology
- Ocular Diseases and Behçet’s Syndrome
- Angiogenesis and VEGF in Cancer
- Musculoskeletal pain and rehabilitation
- Virus-based gene therapy research
- Hydraulic Fracturing and Reservoir Analysis
- Mycobacterium research and diagnosis
- Dyeing and Modifying Textile Fibers
- Complement system in diseases
- Ocular Infections and Treatments
University of Nevada, Reno
2018-2025
Universiti Teknologi MARA
2024
Sarhad University of Science and Information Technology
2021-2023
Regenxbio (United States)
2023
University of the Punjab
2022
Sierra Eye Associates
2020-2021
University Hospital Limerick
2012-2013
Investigate real-world patients receiving faricimab for the treatment of neovascular age-related macular degeneration (nAMD).
The fibroblast growth factor receptor 3 (FGFR3) is warranted as a promising therapeutic target in bladder cancer it described 75% of papillary tumors. Considering this, the present study was conducted to use different approaches computer-aided drug discovery (CADD) identify best binding compounds against active pocket FGFR3. Compared control pyrimidine derivative, identified three lead structures; BDC_24037121, BDC_21200852, and BDC_21206757 with energy value −14.80 kcal/mol, −12.22 −11.67...
Retinal disease treatment delivery is mostly limited to intravitreal injections and slow-release injectable implants due structural barriers in the eye, carry associated adverse effects relatively high burden. The Port Delivery System with ranibizumab (PDS) a novel drug device that surgically implanted into vitreous cavity allows for continuous release of anti-vascular endothelial growth factor (anti-VEGF) ranibizumab, eliminating need frequent while maintaining therapeutic intraocular...
To establish the safety, tolerability, pharmacokinetics, and pharmacodynamics of an intravitreal injection recombinant human complement factor H (CFH), GEM103, in individuals with genetically defined age-related macular degeneration (AMD) geographic atrophy (GA).Phase I single ascending-dose, open-label clinical trial (ClinicalTrials.gov identifier, NCT04246866).Twelve 50 years age or older a confirmed diagnosis foveal GA study eye.Participants were assigned to increasing dose cohorts...
To quantify the areas of burden experienced by patients requiring repeated intravitreal injections (IVI) in management exudative retinal diseases.The validated Questionnaire to Assess Life Impact Treatment Intravitreal Injections survey was administered at four retina clinical practices across US states. The primary outcome measure Burden Score (TBS), a single score assessing overall burden.Of 1416 (n=657 age-related macular degeneration; n=360 diabetic oedema/diabetic retinopathy; n=221...
Investigate retinal fluid changes via a novel deep-learning algorithm in real-world patients receiving faricimab for the treatment of neovascular age-related macular degeneration (nAMD).
Staphylococcus hominis is a Gram-positive bacterium from the staphylococcus genus; it also member of coagulase-negative staphylococci because its opportunistic nature and ability to cause life-threatening bloodstream infections in immunocompromised patients. bacteria have become major concern for medical community. It has drawn attention scientists due evaluation immune evasion tactics development multidrug-resistant strains. This prompted need explore novel therapeutic approaches as an...
This study aimed to assess the time sputum culture conversion (SCC) and its determinants among multidrug-resistant tuberculosis (MDR-TB) patients.This cross-sectional was conducted from January 2019 2020. A total of 252 MDR-TB patients presenting at a tertiary level teaching hospital in Peshawar, Khyber Pakhtunkhwa (KP), were included. The patient's demographic clinical data collected using structured questionnaire. Time SCC calculated initiation treatment till patient had two consecutive...
Nanoparticles are extensively used in biomedical and biotechnological research. Their large surface area, excellent physical properties, high permeability, retention effect make them ideal for applications including diagnosis treatment. Silver nanoparticles proved to be the safest therapeutic uses. In present study, silver (AgNPs) were prepared using various ratios of Ziziphus nummularia fruit extract nitrate solution. The investigated hair growth antibacterial antifungal activities....
Abstract Non‐myelinating Schwann cells (NMSC) play important roles in peripheral nervous system formation and function. However, the molecular identity of these remains poorly defined. We provide evidence that Kir4.1, an inward‐rectifying K+ channel encoded by KCNJ10 gene, is specifically expressed active NMSC. Immunostaining revealed Kir4.1 present terminal/perisynaptic SCs (TPSC), synaptic glia at neuromuscular junctions (NMJ), but not myelinating (MSC) adult mice. To further examine...