A5000385389- Veterinary Oncology Research
- Veterinary Medicine and Surgery
- Head and Neck Surgical Oncology
- Autoimmune and Inflammatory Disorders
- Infectious Diseases and Mycology
- Intestinal Malrotation and Obstruction Disorders
- Tracheal and airway disorders
- Oral Health Pathology and Treatment
- Anatomy and Medical Technology
- Urological Disorders and Treatments
- Hidradenitis Suppurativa and Treatments
- Pediatric Hepatobiliary Diseases and Treatments
- Congenital Diaphragmatic Hernia Studies
- Genetic Syndromes and Imprinting
- Hepatocellular Carcinoma Treatment and Prognosis
- Lung Cancer Diagnosis and Treatment
- Cancer Genomics and Diagnostics
- Virology and Viral Diseases
- Herpesvirus Infections and Treatments
- Myasthenia Gravis and Thymoma
- Streptococcal Infections and Treatments
- Human-Animal Interaction Studies
- Musculoskeletal Disorders and Rehabilitation
- Muscle activation and electromyography studies
- Surgical Simulation and Training
University of Saskatchewan
2024-2025
Colorado State University
2025
Orthopedic Specialty Hospital
2024
Royal University Hospital
2002-2024
University of Minnesota
2016-2021
University of Pennsylvania
2020
University of Minnesota System
2018
Twin Cities Orthopedics
2016
Massey University
2014
Iowa State University
2010
Recent trials in patients with neurodegenerative diseases documented the safety of gene therapy based on adeno-associated virus (AAV) vectors deposited into brain. Inborn errors metabolism are most frequent causes neurodegeneration pre-adulthood. In Sanfilippo syndrome, a lysosomal storage disease which heparan sulfate oligosaccharides accumulate, onset clinical manifestation is before 5 years. Studies mouse model showed that providing missing enzyme α-N-acetyl-glucosaminidase to brain cells...
Cancer is the leading cause of death in dogs, yet there are no established screening paradigms for early detection. Liquid biopsy methods that interrogate cancer-derived genomic alterations cell-free DNA blood being adopted multi-cancer detection human medicine and now available veterinary use. The CANcer Detection Dogs (CANDiD) study an international, multi-center clinical designed to validate performance a novel "liquid biopsy" test developed noninvasive characterization cancer dogs using...
Abstract OBJECTIVE To describe the clinical characteristics, treatments, complications, and outcomes in dogs with nasal planum squamous cell carcinoma (SCC) undergoing local treatment. METHODS A retrospective, multi-institutional study was performed. Medical records were searched to identify diagnosed SCC. Variables recorded from medical statistically analyzed. RESULTS 89 included. The most common presenting complaint a visible mass on (89%). Metastasis detected 12% of at time therapy. Local...
To describe the syndrome of suspected gastroduodenal ulceration/erosion (GUE) in dogs with intrahepatic portosystemic shunts (IHPSS) before and after percutaneous transvenous coil embolization (PTCE). In a multi-institutional, retrospective case series, medical records from 7 specialty hospitals were reviewed to identify IHPSS diagnosed GUE prior or following PTCE July 31, 2013, August 1, 2023. Eleven client-owned divided into 2 groups based on ulcer grade as determined by Veterinary...
To compare demographics and disease characteristics in dogs which peritoneopericardial diaphragmatic hernia (PPDH) had been diagnosed report outcomes after surgical treatment (ST) or conservative (CT).Retrospective study.One hundred twenty-eight (91 ST, 37 CT) PPDH diagnosed.Medical records were reviewed for demographics, perioperative findings, outcomes. Follow-up was obtained via telephone interview email correspondence with owners referring veterinarians. Baseline variables compared...
The adverse effects of intra-abdominal pressure from capnoperitoneum on cardiovascular and pulmonary systems have been well documented, but the portal pressures in dogs with various insufflation is poorly defined. aim present study was to measure effect a range pressure, using direct measurements patients undergoing laparoscopy.
Abstract Objective To describe the signalment, treatment, complications, and outcomes of cats treated surgically for ectopic ureters. Study design Retrospective, multi‐institutional study. Animals Twelve client‐owned cats. Methods Medical records diagnosed with unilateral or bilateral ureters were reviewed analyzed. Data reported included clinical signs, diagnostics, open celiotomy, cystoscopic surgical interventions, outcomes. Results Seven 12 in study population female spayed median age at...
Abstract OBJECTIVE To report the complications and outcomes associated with thoracoscopic cranial mediastinal mass resection in dogs. ANIMALS 49 client-owned dogs that underwent removal. METHODS This was a retrospective cohort study (January 1, 2014, to July 31, 2023), medical records of removal were reviewed. The signalment, history, clinicopathologic features, perioperative complications, long-term outcome recorded. RESULTS Preoperative myasthenia gravis (MG) megaesophagus (ME) identified...
OBJECTIVE To describe surgical management and associated outcomes for dogs with primary spontaneous pneumothorax. ANIMALS 110 client-owned pneumothorax that underwent management. PROCEDURES Medical records at 7 veterinary teaching hospitals were reviewed. Data collected included signalment, history, clinical signs, radiographic CT findings, methods, intraoperative postoperative complications, outcomes, histopathologic findings. Follow-up information was obtained by contacting the referring...
Abstract Objective To report perioperative characteristics, complications, histopathologic diagnosis and outcome in cats undergoing surgical treatment for primary hyperparathyroidism (PHPT). Study design Multi‐institutional, retrospective case series. Animals Thirty‐two client‐owned cats. Methods Medical records of treated with removal 1 or more parathyroid gland(s) confirmed evaluation were reviewed. Cats divided into preoperative ionized calcium (iCa) groups corresponding to the 33rd,...
OBJECTIVE To compare the orthogonal diameter (visual metric) method against a manual perimeter tracing (planimetry) to measure volume of brain tumors in dogs by use MRI scans. SAMPLE 22 sets scans pertaining client-owned with histologically confirmed glioma. PROCEDURES were reviewed 2 operators, and revealing degree gadolinium enhancement that allowed discrimination between tumor tissue healthy parenchyma used. Each operator calculated for each set twice visual metric planimetry methods....
Abstract Objective To describe perioperative characteristics and outcomes of dogs surgically treated for intestinal intussusception. Study design Multi‐institutional, retrospective study. Animals One hundred fifty‐three client‐owned with Methods Dogs were included when they had undergone surgical treatment a confirmed Medical records reviewed demographics clinical data, including complications (graded 1‐4). Follow‐up was obtained via telephone interview owners referring veterinarians....
OBJECTIVE To determine incidence of and risk factors for major complications occurring in dogs within 30 days after cytoreductive surgery performed by a single pair surgeons treatment suspected primary intracranial masses. DESIGN Retrospective cohort study. ANIMALS 160 client-owned that underwent masses between January 2009 December 2015 at veterinary teaching hospital. PROCEDURES Medical records were retrospectively reviewed surgery. Data (eg, signalment, clinical signs, previous...
A 12-year-old spayed female Jack Russell Terrier was presented with pollakiuria and stranguria.Transitional cell carcinoma (TCC) of the urinary bladder trigone urethra diagnosed via CT, cystoscopic, histologic examinations. Azotemia developed 2 weeks following diagnosis, secondary to bilateral ureteral obstruction.Percutaneous antegrade stenting unsuccessful; therefore, a subcutaneous bypass (SUB) device nephrostomy 1 cystostomy catheters surgically placed. Two months placement SUB device,...
Background: Pyoderma gangrenosum is a necrotizing skin disorder of unknown cause. Treatment pyoderma usually entails medical treatments. Surgical treatment generally not successful. Objective: Two patients with their lower extremities are presented. The application and utility microvascular free flap coverage ulcers discussed. Results: Both achieved successful healing flaps. Conclusion: Microvascular may be surgical option for selected gangrenosum.
Abstract Background : Skin and soft tissue infections (SSTIs) are a leading cause of hospital admission engagement with the health care system amongst people who inject drugs (PWID). The current study aims to describe epidemiology SSTIs requiring surgical intervention in Saskatoon, Canada. Methods This retrospective chart review assessed patients primary diagnosis upper limb at St. Paul’s Hospital Royal University (Saskatoon, Canada) between January 1 December 31, 2020. Results 38 eligible...
Background: Pyoderma gangrenosum is a necrotizing skin disorder of unknown cause. Treatment pyoderma usually entails medical treatments. Surgical treatment generally not successful. Objective: Two patients with their lower extremities are presented. The application and utility microvascular free flap coverage ulcers discussed. Results: Both achieved successful healing flaps. Conclusion: Microvascular may be surgical option for selected gangrenosum.
Abstract Objective To determine if environmental variables affect the average daily activity counts (AC) of dogs with osteoarthritis (OA) and/or owners’ perception their dog’s clinical signs or quality life. Methods The AC and Canine Brief Pain Inventory (CBPI) owner questionnaires 62 OA were compared including following: temperature (°C), high low relative humidity (%), total precipitation (mm), barometric pressure (hPa) daylight hours. Results Daily significantly correlated hours, but...
Lasers have been used in surgery for several years. The introduction of the laser into medicine is recognized as an advance technology which has resulted In a better surgical technique to control bleeding (coagulation), resect or excise large tumors (gynecology, neurosurgery, gastroenterology), restore sight blind eye (opthalmology), and remove cancers quickly where otherwise amounts blood loss spreading disease are expected. (primarily at high powers) utilized decrease time foreign body reaction.
Abstract CASE DESCRIPTION An 8-year-old 36.3-kg (79.9-lb) spayed female Rottweiler was evaluated because of anorexia and vomiting. CLINICAL FINDINGS Extrahepatic biliary obstruction (EHBO) secondary to pancreatitis suspected on the basis results from serum biochemical analyses, CT, cytologic examination. TREATMENT AND OUTCOME Only marginal improvement observed after 24 hours traditional medical management; therefore, novel continual drainage achieved with ultrasonographically...