A5039848329- Veterinary Oncology Research
- Veterinary Medicine and Surgery
- Meta-analysis and systematic reviews
- Veterinary Orthopedics and Neurology
- Veterinary Equine Medical Research
- Virus-based gene therapy research
- Congenital Anomalies and Fetal Surgery
- Tracheal and airway disorders
- Human-Animal Interaction Studies
- Surgical Simulation and Training
- Veterinary Practice and Education Studies
- Salivary Gland Tumors Diagnosis and Treatment
- Hepatocellular Carcinoma Treatment and Prognosis
- Congenital Diaphragmatic Hernia Studies
- Oral and Maxillofacial Pathology
- Sarcoma Diagnosis and Treatment
- Ethics in Clinical Research
- Diversity and Career in Medicine
- Anatomy and Medical Technology
- Infectious Diseases and Mycology
- Neuroblastoma Research and Treatments
- Clinical practice guidelines implementation
- Lymphatic Disorders and Treatments
- Statistical Methods in Clinical Trials
- Medical Education and Admissions
University of California, Davis
2016-2025
Veterinary Medical Teaching Hospital
2023
Hudson Institute
2017-2020
John Wiley & Sons (United States)
2017-2020
Moss Landing Marine Laboratories
2017-2020
American College of Veterinary Surgeons
2017
University of Zurich
2017
California University of Pennsylvania
2016
University of Pennsylvania
2012-2016
Hospital of the University of Pennsylvania
2016
The updated VCOG-CTCAE v2 guidelines contain several important updates and additions since the last update (v1.1) was released in 2011 published within Veterinary Comparative Oncology 2016. As Cooperative Group (VCOG) is no longer an active entity, original authors contributors to v1.0 v1.1 were consulted for input, additional co-authors sought expansion refinement of adverse event (AE) categories. includes expanded neurology, cardiac immunologic AE sections, addition procedural-specific...
Two FGF4 retrogenes on chromosomes 12 (12-FGF4RG) and 18 (18-FGF4RG) contribute to short-limbed phenotypes in dogs. 12-FGF4RG has also been associated with intervertebral disc disease (IVDD). Both of these were found be widespread among dog breeds allele frequencies ranging from 0.02 1; however, their additive contribution is unknown. Surgical cases IVDD (n = 569) evaluated for age onset, calcification, genotypes the retrogenes. Multivariable linear regression analysis identified presence...
Abstract OBJECTIVE To describe the clinical characteristics, treatments, complications, and outcomes in dogs with nasal planum squamous cell carcinoma (SCC) undergoing local treatment. METHODS A retrospective, multi-institutional study was performed. Medical records were searched to identify diagnosed SCC. Variables recorded from medical statistically analyzed. RESULTS 89 included. The most common presenting complaint a visible mass on (89%). Metastasis detected 12% of at time therapy. Local...
Abstract OBJECTIVE To determine the prevalence and severity of gastrointestinal mucosal lesions in dogs with intrahepatic portosystemic shunts (IHPSS), to compare IHPSS before after treatment percutaneous transvenous coil embolization (PTCE) based on capsule endoscopy (CE). METHODS A prospective clinical trial was performed from June 1, 2020, March 2022. Ten client-owned diagnosed by use CT angiography were included. Dogs administered a device prior 1 month following PTCE. Outcomes compared...
To describe reporting of key methodological elements associated with type II error in published reports small animal randomized controlled trials (RCTs) and to determine the statistical power a subset RCTs negative results.Descriptive literature survey.Reports parallel-group clinical 11 English-language veterinary journals from 2005 2012.Predefined criteria were used identify trial primary outcomes classify results as or positive. Details sample size determination use confidence intervals...
OBJECTIVE To describe development and initial psychometric testing of an owner-reported questionnaire designed to standardize measurement general quality life (QOL) in dogs with cancer. DESIGN Key-informant interviews, development, field trial. SAMPLE Owners 25 cancer for item pretesting owners 90 reliability validity testing. PROCEDURES Standard methods instruments intended measure subjective states were used. Items generated, selected, scaled, pretested content, meaning, readability....
OBJECTIVE To evaluate potential associations between surgical approach and complication rate, progression-free survival time, disease-specific time in cats with mammary adenocarcinoma. DESIGN Retrospective case series. ANIMALS 107 client-owned cats. PROCEDURES Medical records of that underwent excision adenocarcinoma by means a unilateral or bilateral (staged single-session) mastectomy at 9 hospitals 1991 2014 were reviewed. Relevant clinicopathologic data details adjuvant treatments...
Abstract Objective To describe the use and outcome of a single, simple continuous, barbed suture line for prophylactic, total laparoscopic gastropexy in dogs. Study Design Multi‐center, retrospective case series. Animals Sixty‐three client‐owned Methods Medical records dogs undergoing using at 4 academic veterinary hospitals from 2011‐2015 were reviewed. Data collected included signalment, procedure time, procedure‐associated complications, short‐term long‐term outcome. All procedures...
To describe the operative technique, complications, and conversion rates for laparoscopic liver biopsy (LLB) in dogs evaluate short-term clinical outcome that underwent procedure.Retrospective case series.106 client-owned dogs.Medical records were reviewed to identify an LLB with a single-port or multiport technique at either of 2 veterinary teaching hospitals from August 2003 September 2013. Demographic laboratory data, preoperative administration fresh frozen plasma, procedural diagnostic...
Abstract OBJECTIVE To determine the percentage of dogs surviving to hospital discharge and identify factors associated with death prior among undergoing surgery because primary splenic torsion (PST). DESIGN Retrospective case series. ANIMALS 102 client-owned dogs. PROCEDURES Medical records a confirmed diagnosis PST that underwent between August 1992 May 2014 were reviewed. History, signalment, results physical examination preoperative bloodwork, method splenectomy, concurrent surgical...
Abstract Objective To report the morbidity and mortality associated with adrenalectomy cavotomy for resection of invasive adrenal neoplasms in dogs evaluate risk factors perioperative outcomes. Study design Retrospective study. Animals Forty‐five client‐owned dogs. Methods Dogs that underwent open masses tumor thrombus extending into vena cava were included. Clinicopathologic data harvested from medical records. Selected clinical, imaging, operative variables statistically evaluated as...
Abstract Objective To evaluate the long‐term outcome of video‐assisted thoracoscopic (VATS) thoracic duct ligation (TDL) and pericardectomy for treatment chylothorax in dogs. Study design Multi‐institutional retrospective study. Animals Thirty‐nine client‐owned Methods Dogs were included if they had undergone a VATS TDL at least 1‐year follow‐up or died within 1 postoperative year. Medical records evaluated, recorded data clinicopathological diagnostic imaging results, surgical findings,...
Abstract OBJECTIVE To compare outcomes for laparoscopic ovariectomy (LapOVE) and laparoscopic-assisted ovariohysterectomy (LapOVH) in dogs. DESIGN Retrospective case series. ANIMALS 278 female PROCEDURES Medical records of dogs that underwent sterilization between 2003 2013 were reviewed. History, signalment, results physical examination, preoperative diagnostic testing, details the surgical procedure, durations anesthesia surgery, intraoperative immediate postoperative (ie, during...
Abstract Background Lower urinary tract transitional cell carcinoma (TCC) is an important but rarely described disease of cats. Objectives To report the clinical characteristics, treatments, and outcomes in a cohort cats with lower TCC to test identified variables for prognostic relevance. Animals One‐hundred eighteen client‐owned carcinoma. Methods Medical records were retrospectively reviewed obtain information regarding outcomes. Recorded analyzed statistically. Results Median age...
Abstract Hemangiosarcoma (HSA) of bone and telangiectatic osteosarcoma (tOSA) can appear similar histologically, but differ in histogenesis (malignant endothelial cells versus osteoblasts), may warrant different treatments. Immunohistochemistry (IHC) for cell marker factor VIII‐related antigen/von Willebrand (FVIII‐RAg/vWF) is a well‐documented ancillary test to confirm HSA diagnoses soft tissues, its use osseous rarely described. Archived samples 54 primary appendicular tumours previously...
To compare demographics and disease characteristics in dogs which peritoneopericardial diaphragmatic hernia (PPDH) had been diagnosed report outcomes after surgical treatment (ST) or conservative (CT).Retrospective study.One hundred twenty-eight (91 ST, 37 CT) PPDH diagnosed.Medical records were reviewed for demographics, perioperative findings, outcomes. Follow-up was obtained via telephone interview email correspondence with owners referring veterinarians. Baseline variables compared...
To report outcome and complications after percutaneous transvenous coil embolization (PTCE) evaluate the clinical, laboratory, imaging changes in dogs with intrahepatic portosystemic shunts (IHPSS) pre-PTCE post-PTCE.Prospective clinical trial.Twenty-five (15 subgroup) IHPSS.Clinical signs, hematologic, biochemical parameters were recorded before 3 months PTCE. All received same medical treatment underwent In subgroup, ultrasonography, hepatic portal scintigraphy, computed...
Abstract Background Histiocytic sarcoma affecting the central nervous system (CNS HS) in dogs may present as primary or disseminated disease, often characterized by inflammation. Prognosis is poor, and imaging differentiation from other CNS tumors can be problematic. Objective To characterize clinicopathological inflammatory features, breed predisposition, survival with HS. Animals One hundred two HS, 62 meningioma. Methods Retrospective case series. Records were reviewed for results of...
To document outcomes of thoracoscopic treatment idiopathic chylothorax (IC) in dogs with and without constrictive pericardial physiology (CPP) evaluate patterns chyle flow redistribution after thoracic duct ligation (TDL).26 client-owned dogs.In this prospective cohort study, echocardiography cardiac catheterization were performed to CPP IC. Thoracoscopic TDL pericardiectomy was if present (TDL/P group). Dogs evidence underwent alone (TDL preoperative, immediate postoperative, 3-month...
To evaluate randomisation mechanisms in the veterinary literature, all trials defined as 'randomised' were extracted from five leading journals for year 2013. Three blinded investigators evaluated (1) if random sequence generation was actually non-random, and (2) whether method (CONSORT item 8A) (3) type of 8B) reported. Trialists contacted via email to establish willingness respond questions on procedures, reporting improved following a suggestion use CONSORT 2010 guideline. Seven per cent...
Medical records of 22 dogs treated with carboplatin (n = 8) or and cytarabine 14) chemotherapy for relapsed refractory lymphoma between 2000 2013 were retrospectively reviewed. The clinical response rate was 18.2% (4/22). Median time to progression 18 days (56 responders; 12 non-responders, P 0.0006). overall survival 28 (109 21 0.0007). Thrombocytopenia neutropenia occurred in 84.2% (16/19) 52.6% (10/19), respectively. Grade IV thrombocytopenia 56.3% (9/16) 60.0% (6/10), Dogs that received...
Objective To determine the sensitivity, specificity, and predictive value of ultrasonography for localizing hepatic masses in dogs to identify patient factors associated with diagnostic accuracy. Study Design Retrospective cross‐sectional study. Animals Client‐owned (n = 137). Methods Medical records diagnosed a solitary mass on abdominal ultrasound confirmed by laparotomy or laparoscopy were reviewed. Location predicted was compared location identified at surgery. Ultrasound exams performed...