A5044344680- Dialysis and Renal Disease Management
- Global Maternal and Child Health
- Pediatric Urology and Nephrology Studies
- Parathyroid Disorders and Treatments
- Central Venous Catheters and Hemodialysis
- Vitamin D Research Studies
- Neonatal Health and Biochemistry
- Adolescent and Pediatric Healthcare
- Organ Donation and Transplantation
- Renal Diseases and Glomerulopathies
- Urinary Tract Infections Management
- Renal Transplantation Outcomes and Treatments
- Poisoning and overdose treatments
- Acute Kidney Injury Research
- Pharmacological Effects and Toxicity Studies
- Biomedical Research and Pathophysiology
- Amino Acid Enzymes and Metabolism
- Kidney Stones and Urolithiasis Treatments
- Metabolism and Genetic Disorders
- Renal function and acid-base balance
- Urinary Bladder and Prostate Research
- Pancreatitis Pathology and Treatment
- Healthcare cost, quality, practices
- Autoimmune Bullous Skin Diseases
- Renal and related cancers
St.John's Medical College Hospital
2014-2025
Creative Commons
2023
Jawaharlal Institute of Post Graduate Medical Education and Research
2023
Roche (United Kingdom)
2021
St. John's National Academy of Health Sciences
2017
St. John's School
2011
This guideline addresses the use of hypoxia-inducible factor prolyl hydroxylase inhibitors (HIF-PHIs) in patients >18 years with chronic kidney disease (CKD) and anemia South Asia (Bangladesh, Bhutan, Nepal, India, Pakistan, Sri Lanka). It also summarizes recommendations for treatment individual HIF-PHI molecules under two categories: dialysis-dependent non-dialysis-dependent CKD patients. The do not apply to pediatric (≤12 years) adolescent (12 18) or those primary secondary other causes...
Background: Gaining access to the peritoneal cavity is a critical step in laparoscopic surgeries and associated with risk of complications. The two most commonly used techniques for pneumoperitoneum creation are open (Hasson cannula) closed (Veress needle) methods. This study aims compare these terms procedural efficiency, intraoperative postoperative complications, long-term outcomes. Methods: randomized controlled trial included 50 patients undergoing elective at tertiary care hospital....
The prevalence of pediatric chronic kidney disease (CKD) ranges from 15 to 74.7 cases per 1 million children.1Harambat J. Van Stralen K.J. Kim J.J. Tizard E.J. Epidemiology in children.Pediatr Nephrol. 2012; 27: 363-373Crossref PubMed Scopus (571) Google Scholar Mortality among children who progress end-stage (ESKD) is 30 50 times higher compared that the general population.1Harambat Scholar, 2Mitsnefes M.M. Laskin B.L. Dahhou M. et al.Mortality risk initially treated with dialysis for...
IntroductionThere is a disparity in the availability of healthcare for children resource-constrained countries. The International Pediatric Nephrology Association (IPNA) commissioned an initiative exploring challenges care with kidney disease low/middle-income countries(L/MICs) focus on human, diagnostic, and therapeutic resources.MethodsA survey was sent by e-mail to all members IPNA its affiliated regional/national societies residing L/MICs. Data extracted from individual responses after...
Background: Peritoneal dialysis (PD) is the preferred modality of renal replacement therapy in children with end-stage disease (ESRD). In developing countries, challenges initiating and sustaining chronic peritoneal (CPD) are many not well-described literature. Methods: This was a retrospective study aged 0–18 years on manual PD. The objective to compare clinical (growth) outcomes (dialysis adequacy peritonitis rates) young low body weight (LBW; ≤15 kg) CPD weighing >15 kg. Results: We...
The optimal treatment regimen for correcting 25-hydroxyvitamin D (25OHD) deficiency in children with chronic kidney disease (CKD) is not known. We compared cholecalciferol dosing regimens achieving and maintaining 25OHD concentrations ≥30 ng/mL CKD stages 2-4.An open-label, multicentre randomized controlled trial <30 1:1:1 to oral 3000 IU daily, 25 000 weekly or 100 monthly 3 months (maximum three intensive courses). In those ng/mL, 1000 daily (maintenance course) was given up 9 months....
Abstract The nutritional management of neonates with kidney disease is complex. There may be significant differences in needs based on the duration and cause dysfunction, including acute injury (AKI) chronic (CKD). Furthermore, treatment modality, (continuous renal replacement therapy peritoneal dialysis [PD]) (intermittent hemodialysis PD) approaches differentially affect losses dietary needs. In this review, we discuss pathophysiology compromised nutrition AKI CKD. We also summarize...
Cyclosporine A (CyA) is an effective agent for the treatment of glucocorticoid-dependent idiopathic nephrotic syndrome (GCDNS), but costs are prohibitive in resource-poor societies. The objectives this study were to evaluate efficacy and safety reducing dose CyA by co-administering ketoconazole. prospective targeting children 2-18 years age with GCDNS remission monotherapy was conducted. reduced 50% ketoconazole added at 25% recommended therapeutic dose, drug levels adverse effects (AE)...
Sodium retention is the hallmark of idiopathic nephrotic syndrome (INS). could be secondary to activation renin-angiotensin-aldosterone axis or due an intrinsic Na<sup>+</sup> K<sup>+</sup> ATPase in cortical collecting duct. Urine potassium/urine potassium + urine sodium (UK<sup>+</sup> /UK<sup>+</sup> UNa<sup>+</sup>) a surrogate marker for aldosterone activity and can useful differentiating primary from children with INS. This was cross-sectional study INS, presenting our center June 2007...
Primary hyperoxaluria (PH) has heterogeneous renal manifestations in infants and children. This often leads to delay diagnosis. In the past 3 years, genetic samples were sent for seven children with a clinical diagnosis of PH. Their medical records reviewed presentation outcomes. Of children, three males. The median age was 4.9 years youngest presenting at months age. Nephrolithiasis, most common associated dysfunction two Two no significant history presented end-stage disease (ESRD)....
Seroconversion following hepatitis B vaccination is low in children with chronic kidney disease (CKD). This study aimed to assess the seroconversion and persistence of protective immunity CKD. prospective observational was conducted a tertiary pediatric nephrology centre maintenance antibody titers (>10 mIU/mL) at one year (10 μg 0, 1, 2 months) CKD Stages II V. Those who did not seroconvert after schedule were re-vaccinated, checked. Categorical data expressed as proportions analyzed using...
Aims The prevalence of vitamin D deficiency is high in children with chronic kidney disease (CKD). However, current dosing recommendations are based on limited pharmacokinetic (PK) data. This study aimed to develop a population PK model colecalciferol that can be used optimise this population. Methods Data from 83 CKD were using nonlinear mixed effects modelling approach. Serum creatinine and type (glomerular vs . nonglomerular disease) investigated as covariates, optimal was determined...