A5005529926- Acute Kidney Injury Research
- Sepsis Diagnosis and Treatment
- Dialysis and Renal Disease Management
- Innovative Microfluidic and Catalytic Techniques Innovation
- Renal Diseases and Glomerulopathies
- Renal function and acid-base balance
- Biomedical Research and Pathophysiology
- Cellular transport and secretion
- Chemical Synthesis and Analysis
- Complement system in diseases
- Body Composition Measurement Techniques
- Antibiotics Pharmacokinetics and Efficacy
- Antibiotic Use and Resistance
- Renal and related cancers
- Microscopic Colitis
- Renal Transplantation Outcomes and Treatments
- Hemodynamic Monitoring and Therapy
- Genetic and Kidney Cyst Diseases
- Birth, Development, and Health
- Inflammatory Bowel Disease
- Blood groups and transfusion
- Neonatal Respiratory Health Research
- Cardiac Arrest and Resuscitation
- Pneumonia and Respiratory Infections
- Biochemical Analysis and Sensing Techniques
Eastern Health
2024-2025
Amrita Vishwa Vidyapeetham
2017-2025
St.John's Medical College Hospital
2014-2024
National Centre for Biological Sciences
2024
St. John's National Academy of Health Sciences
2022
Amrita Institute of Medical Sciences and Research Centre
2016-2021
AbbVie (United States)
2019-2021
Abbott (United States)
2005-2012
Abbott Fund
2004-2007
All India Institute of Medical Sciences
2004-2006
Improving the quality of hospital antibiotic use is a major goal WHO's global action plan to combat antimicrobial resistance. The WHO Essential Medicines List Access, Watch, and Reserve (AWaRe) classification could facilitate simple stewardship interventions that are widely applicable globally. We aimed present data on patterns paediatric AWaRe be used for local national interventions.1-day point prevalence survey prescription were combined from two independent networks: Global Antimicrobial...
Mediastinitis occurs after cardiac surgery and is a major threat to patient's life due postoperative bleeding deep sternal wound infection. Major challenge in treating this condition that it demands material should adhere the applied site act as both hemostatic an antibacterial agent. On basis of we have developed situ forming tissue adhesive chitin–fibrin (CH-FB) gel with tigecycline loaded gelatin nanoparticles (tGNPs) for controlling preventing bacterial Spherical shaped tGNPs (231 ± 20...
Technologies that enable rapid screening of diverse reaction conditions are critical importance to methodology development and optimization, especially when molecules high complexity scarcity involved. The lack a general solid dispensing method for chemical reagents on micro- nanomole scale prevents the full utilization technologies. We herein report technology in which glass beads coated with (ChemBeads) delivery quantities efficiently. By exploring concept preferred sets, flexibility...
Background: Atypical hemolytic uremic syndrome (aHUS), an important cause of acute kidney injury (AKI), is characterized by dysregulation the alternative complement pathway. Autoantibodies to factor H (FH), a chief regulator this pathway, account for distinct subgroup. While high anti-FH titers predict relapse, they do not correlate well with disease activity and their functional characterization required. Methods: Of 781 patients <18-year-old aHUS in nationwide database from 2007 2018, 436...
The prevalence of antimicrobial resistance in India is among the highest world. Antimicrobial use inpatient settings an important driver resistance, but poorly characterized, particularly hospitalized children. In this study, conducted as part Global Resistance, Prescribing, and Efficacy Neonates Children (GARPEC) project, we examined indications use, well agents used children by conducting four point surveys six hospitals between February 2016 2017. A total 681 were across all survey days,...
High blood pressure (BP) in children and adolescents is becoming one of the most common health conditions worldwide much more widely prevalent than previously thought.To estimate prevalence high BP India identify associated factors.This cross-sectional study a secondary analysis data from Comprehensive National Nutrition Survey (CNNS, 2016-2018), which used multistage, stratified, probability proportion to size cluster sampling design enroll nationally representative sample households...
To study (1) epidemiological factors, clinical profile and outcomes of COVID-19 related multisystem inflammatory syndrome in children (MIS-C), (2) across age groups, (3) medium-term (4) parameters associated with disease severity.
South Asians are a high-risk group for type 2 diabetes and coronary heart disease. We sought to determine ethnic differences in newborn adiposity comparing (SA) White Caucasians (Whites).Seven hundred ninety pregnant women (401 SA, 389 Whites) their full-term offspring from two birth cohorts Canada were analyzed. Pregnant completed health assessment including 75-g oral glucose tolerance test assess dysglycemia. Birthweight, length, waist hip circumference, triceps subscapular skinfold...
Abstract Background Information on infectious complications following acute severe ulcerative colitis (ASUC) is limited. The aim of this study was to determine rates infections ASUC treatment and the associated risk factors, using data from Asian Organization for Crohn’s Colitis (AOCC) Australia New Zealand IBD Consortium (ANZIBDC). Methods We collected medical records patients diagnosed with according Truelove Witts criteria January 2015 December 2022 across AOCC ANZIBDC. analyzed...
Abstract Background There are limited comparisons of clinical outcomes acute severe ulcerative colitis (ASUC) between East Asian (EA) and Western countries many currently used scoring systems based on populations. We developed a predictive model using ASUC data from EA patients assessed its ability to predict in an Australia/New Zealand (ANZ) cohort. Methods This retrospective international study was conducted across 23 referral hospitals ANZ. Patients who met Truelove Witts criteria for...
A novel methodology for the hydration of alkynes in superheated water using microwave irradiation is reported. Extension this to hydroamination also described.
Information on current practices in India for management of renal replacement therapy (RRT) acute kidney injury (AKI) is lacking. We mailed a questionnaire to 26 pediatric nephrology centers across obtain information the choice dialysis modality AKI children. Acute intermittent peritoneal was available at all surveyed, whereas hemodialysis and continuous RRT were 86% 17% centers, respectively. Peritoneal predominant (accounting more than 80% dialysis) 14 22 while 4 used commonly. The most...
BackgroundInformation about antimicrobial use is scarce and poorly understood among neonatal intensive care units (NICUs) in India. In this study, we describe eight NICUs using four point prevalence surveys (PPSs).MethodsAs part of the Global Antimicrobial Resistance, Prescribing, Efficacy Neonates Children (GARPEC) one-day, cross-sectional, hospital-based PPSs were conducted times between 1 February 2016 28 2017 NICUs. Using a standardized web-based electronic data entry form, detailed...
The coronavirus outbreak is a rapidly evolving pandemic, placing unprecedented strain on health-care systems. COVID-19 presents challenges for management of children with renal diseases, especially those receiving long-term immunosuppressive medications, including transplant recipients and chronic kidney disease acute injury requiring dialysis. Our preparedness managing this vulnerable group the need hour. purpose article to provide guidance caregivers health care personnel involved in...
Abstract Background Upadacitinib is a novel selective Janus Kinase (JAK) inhibitor which has recently been approved for use in ulcerative colitis. Clinical trials have rigorous criteria and excluded patients with prior exposure to JAK inhibitors. Given limited real-world effectiveness data we examined outcomes of treated upadacitinib colitis population, focus on tofacitinib exposure. Methods This retrospective, multi-centre study recruited commencing moderate-to-severe from September 2022...
Abstract Technologies that enable rapid screening of diverse reaction conditions are critical importance to methodology development and optimization, especially when molecules high complexity scarcity involved. The lack a general solid dispensing method for chemical reagents on micro‐ nanomole scale prevents the full utilization technologies. We herein report technology in which glass beads coated with (ChemBeads) delivery quantities efficiently. By exploring concept preferred sets,...