Despoina Gkentzi
A5000986139- Neonatal and Maternal Infections
- COVID-19 Impact on Reproduction
- Vaccine Coverage and Hesitancy
- Pneumonia and Respiratory Infections
- SARS-CoV-2 and COVID-19 Research
- Sepsis Diagnosis and Treatment
- COVID-19 Clinical Research Studies
- Bacterial Infections and Vaccines
- Antibiotic Use and Resistance
- Neonatal Respiratory Health Research
- Streptococcal Infections and Treatments
- Influenza Virus Research Studies
- Respiratory viral infections research
- Congenital Heart Disease Studies
- Cytomegalovirus and herpesvirus research
- Neonatal Health and Biochemistry
- Kawasaki Disease and Coronary Complications
- Nosocomial Infections in ICU
- Bacterial Identification and Susceptibility Testing
- COVID-19 and Mental Health
- Infant Development and Preterm Care
- Pregnancy and preeclampsia studies
- Coronary Artery Anomalies
- Child and Adolescent Health
- Emergency and Acute Care Studies
General University Hospital of Patras
2016-2025
University of Patras
2014-2025
University Hospital of Ioannina
2024
University of Ioannina
2024
Hippocration General Hospital
2024
Imperial College Healthcare NHS Trust
2014-2023
Gollwitzer-Meier-Klinik
2023
National and Kapodistrian University of Athens
2023
Research Institute Hospital 12 de Octubre
2023
University of Nicosia
2022
Improving the quality of hospital antibiotic use is a major goal WHO's global action plan to combat antimicrobial resistance. The WHO Essential Medicines List Access, Watch, and Reserve (AWaRe) classification could facilitate simple stewardship interventions that are widely applicable globally. We aimed present data on patterns paediatric AWaRe be used for local national interventions.1-day point prevalence survey prescription were combined from two independent networks: Global Antimicrobial...
Sepsis represents a common cause of morbidity in the Neonatal Intensive Care Unit (NICU). Our objective was to assess value clinical and laboratory parameters predicting septicemia (positive blood culture) NICU infants. In first part present study (derivation cohort) we retrospectively reviewed files 120 neonates with symptoms suspected sepsis identified associated proven on day culture taken, as well 24 h 48 earlier. These were combined into prediction score (SPS). Subsequently (validation...
The objective of this study was to assess the ability acute dimercaptosuccinic acid (DMSA) scintigraphy for revealing vesicoureteral reflux (VUR) in young children after a first febrile urinary tract infection (UTI).Children aged<or=24 months and were admitted with UTI during 5-year period evaluated. DMSA reveal dilating (grades 3-5) or severe 4-5) VUR assessed by comparing scan findings those voiding cystourethrography.Of 296 included, 46 had 25 VUR. Abnormal results associated an odds...
This study was conducted to assess the variation in prescription practices for systemic antimicrobial agents used prophylaxis among pediatric patients hospitalized 41 countries worldwide.Using standardized Antibiotic Resistance and Prescribing European Children Point Prevalence Survey protocol, a cross-sectional point-prevalence survey at 226 hospitals from October 1 November 30, 2012.Overall, 17693 were surveyed 36.7% of them received antibiotics (n = 6499). Of 6818 inpatient children, 2242...
The number of paediatric emergency department (ED) visits and hospital admissions was recorded in a tertiary referral centre during the first year COVID-19, March 2020-February 2021, compared with those preceding year.The reason visit admission were prospectively from 15,087 patients' files.A substantial decline total increase rate documented COVID-19 to (10691 vs 4396 patients, 22.59% 18.15% (OR: 1.316, CI 95%: 1.208-2.242, p < 0.0001), respectively). Fever and/or respiratory symptoms...
The World Health Organization (WHO)'s Research and Development (R&D) Blueprint for Action to Prevent Epidemics, a plan of action, highlighted several infectious diseases as crucial targets prevention. These infections were selected based on thorough assessment factors such transmissibility, infectivity, severity, evolutionary potential. In line with this blueprint, the VACCELERATE Site Network approached disease experts rank listed in WHO R&D according their perceived risk triggering...
Abstract Multisystem inflammatory syndrome in children (MIS-C) is a rare but severe hyperinflammatory condition that may occur following SARS-CoV-2 infection. This retrospective, descriptive study of hospitalized with multisystem 12 tertiary care centers from 3/11/2020 to 12/31/2021. Demographics, clinical and laboratory characteristics, treatment outcomes are described. Among 145 patients (95 males, median age 8.2 years) included, 123 met the WHO criteria for MIS-C, while 112 (77%) had...
Objective To describe the epidemiology of neonatal infections and antimicrobial use in Greek Neonatal Units (NNUs) order to develop national, evidence-based guidelines on empiric for sepsis Greece. Design Retrospective analysis prospectively collected infection surveillance data from 2012 2015, together with a Point Prevalence Survey (PPS) collection local policies. Setting 16 NNUs Greece participating neonIN network Patients Newborns who had positive blood, cerebrospinal fluid or urine...
Inflammation plays a crucial role in diabetes and obesity through macrophage activation. Macrophage chemoattractant protein-1 (MCP-1), activin-A, clusterin are chemokines with known roles obesity. The aim of this study is to investigate their possible diagnostic and/or early prognostic values children adolescents type-1 mellitus (T1DM). Methods: We obtained serum samples from history T1DM or obesity, order measure compare MCP-1, concentrations. Results: Forty-three subjects were included...
Invasive meningococcal disease (IMD) remains a major public health challenge due to its rapid progression, which may lead severe sequelae or death in children and adolescents. Published data on IMD are limited Greece many EU countries. In the present study, patients under 16 years of age with were retrospectively identified from files Hellenic National Meningitis Reference Laboratory (HNML) 2010–2020, their medical records tracked corresponding hospitals. Demographic, clinical,...
Objective: To evaluate if the number of admitted extremely preterm (EP) infants (born before 28 weeks gestational age) differed in neonatal intensive care units (NICUs) SafeBoosC-III consortium during global lockdown when compared to corresponding time period 2019. Design: This is a retrospective, observational study. Forty-six out 79 NICUs (58%) from 17 countries participated. Principal investigators were asked report following information: (1) Total EP infant admissions their NICU 3 months...
In this nationwide retrospective study, a substantial decline in the incidence of multisystem inflammatory syndrome children over 3 successive pandemic waves characterized by different severe acute respiratory coronavirus 2 variants was documented-from 3.4 1000 to 1.1 and finally 0.25 confirmed positive cases (P < 0.0001), respectively, whereas clinical findings severity did not significantly vary.