A5079080910- Geological Studies and Exploration
- Geology and Paleoclimatology Research
- Geological formations and processes
- Hydrocarbon exploration and reservoir analysis
- Paleontology and Evolutionary Biology
- Paleontology and Stratigraphy of Fossils
- Functional Brain Connectivity Studies
- Evolution and Paleontology Studies
- Geological and Geochemical Analysis
- Methane Hydrates and Related Phenomena
- Cell Image Analysis Techniques
- Advanced Neuroimaging Techniques and Applications
- Geochemistry and Geologic Mapping
- Electron and X-Ray Spectroscopy Techniques
- Geological Modeling and Analysis
- Hydrology and Sediment Transport Processes
- Clay minerals and soil interactions
- Ichthyology and Marine Biology
- Bioinformatics and Genomic Networks
- Mental Health Research Topics
- Soil and Unsaturated Flow
- Genetic Associations and Epidemiology
- Advanced MRI Techniques and Applications
- Archaeology and Natural History
- Marine and environmental studies
University of Alaska Fairbanks
2013-2024
University of Oxford
2014-2024
Wellcome Centre for Integrative Neuroimaging
2014-2024
John Radcliffe Hospital
2019
University of Otago
2012-2014
Utah AIDS Foundation
2011
University of Alaska System
2010
Louisiana State University Health Sciences Center Shreveport
2009
Indiana University of Pennsylvania
2006
Lamont-Doherty Earth Observatory
2006
UK Biobank is a large-scale prospective epidemiological study with all data accessible to researchers worldwide. It currently in the process of bringing back 100,000 original participants for brain, heart and body MRI, carotid ultrasound low-dose bone/fat x-ray. The brain imaging component covers 6 modalities (T1, T2 FLAIR, susceptibility weighted Resting fMRI, Task fMRI Diffusion MRI). Raw processed from first 10,000 imaged subjects has recently been released general research access. To...
There is strong evidence of brain-related abnormalities in COVID-19
Dealing with confounds is an essential step in large cohort studies to address problems such as unexplained variance and spurious correlations. UK Biobank a powerful resource for studying associations between imaging non-imaging measures lifestyle factors health outcomes, part because of the subject numbers. However, resulting high statistical power also raises sensitivity confound effects, which therefore have be carefully considered. In this work we describe set possible (including...
Brain imaging can be used to study how individuals’ brains are aging, compared against population norms. This inform on aspects of brain health; for example, smoking and blood pressure seen accelerate aging. Typically, a single ‘brain age’ is estimated per subject, whereas here we identified 62 modes subject variability, from 21,407 subjects’ multimodal data in UK Biobank. The represent different showing distinct patterns functional structural change, association with genetics, lifestyle,...
The brain signature and genetic basis of handedness are unclear. Wiberg et al. show that left-handers have higher functional connectivity between language networks, identify four genomic regions associated with handedness. Variants within these appear, by influencing architecture, to predispose both left-handedness certain neuropsychiatric diseases.
Abstract There is strong evidence for brain-related abnormalities in COVID-19 1–13 . It remains unknown however whether the impact of SARS-CoV-2 infection can be detected milder cases, and this reveal possible mechanisms contributing to brain pathology. Here, we investigated changes 785 UK Biobank participants (aged 51–81) imaged twice, including 401 cases who tested positive with between their two scans, 141 days on average separating diagnosis second scan, 384 controls. The availability...
Abstract We have previously identified a network of higher-order brain regions particularly vulnerable to the ageing process, schizophrenia and Alzheimer’s disease. However, it remains unknown what genetic influences on this fragile are, whether can be altered by most common modifiable risk factors for dementia. Here, in ~40,000 UK Biobank participants, we first show significant genome-wide associations between seven clusters implicated cardiovascular deaths, schizophrenia, Parkinson’s...
Research Article| May 01, 1998 Recognition of interfluve sequence boundaries: Integrating paleopedology and stratigraphy Paul J. McCarthy; McCarthy 1Department Earth Sciences, University Western Ontario, London, Ontario N6A 5B7, Canada Search for other works by this author on: GSW Google Scholar A. Guy Plint Author Article Information Publisher: Geological Society America First Online: 02 Jun 2017 Online ISSN: 1943-2682 Print 0091-7613 Geology (1998) 26 (5): 387–390....
While humans are known to have several premotor cortical areas, secondary motor cortex (M2) is often considered be the only higher-order area of mouse brain and thought combine properties various human cortices. Here, we show that axonal tracer, functional connectivity, myelin mapping, gene expression, optogenetics data contradict this notion. Our analyses reveal three areas in mouse, anterior-lateral (ALM), M2 (aM2), posterior-medial (pM2), with distinct structural, functional, behavioral...
To date, discussion of changes in alluvial style and the character palaeosols relation to accommodation sediment supply on floodplains has primarily been from a conceptual standpoint: few case studies are available against which test ideas. One hundred thirty metres non‐marine strata Dunvegan Formation were examined 14 closely spaced sections canyon Kiskatinaw River, NE British Columbia, Canada. This site was located about 120 km inland transgressive limit contemporary marine shoreline...
The Upper Cretaceous Cantwell Formation in Denali National Park and Preserve (DENA), Alaska, contains an unparalleled fossil avian biodiversity. Formation, thousands of metres thick, was deposited near its current latitude is exposed throughout much DENA elsewhere the central Alaska Range. comprises a lower, dominantly fluvial sedimentary unit upper, mostly volcanic unit. Sedimentation lower mainly alluvial fan, braided meandering stream, lacustrine environments, with possible...
The posterior-anterior shift in aging (PASA) is a commonly observed phenomenon functional neuroimaging studies of aging, characterized by age-related reductions occipital activity alongside increases frontal activity. In this work we have investigated the hypothesis as to whether PASA also manifested brain network measures such degree, clustering coefficient, path length and local efficiency. We performed statistical analysis upon networks derived from fMRI dataset containing data healthy...
Abstract A basic sedimentological and palaeopedological framework is now in place for non‐marine sequence models. The variability of interfluve palaeosols has not, however, been systematically documented, nor have the stratigraphic implications that incorporated into Interfluve palaeosol deltaic Dunvegan Formation, NE British Columbia, Canada, investigated, which a detailed allostratigraphic palaeogeographic developed, based on abundant well (> 2300 logs) outcrop 60 sections) control....
Little is understood about chemical weathering processes in Alaskan arctic soils, where moisture generally not limited but acidity varies and the average soil temperature close to or below freezing. Weathering reactions convert primary minerals into secondary clay minerals. Silty loam textured soils from three sites moist acidic tundra (MAT) nonacidic (MNT) northern Arctic Foothills, Alaska, were characterized with emphasis on origin of The MNT had a discontinuous thinner organic layer,...
Abstract UK Biobank is a large-scale prospective epidemiological study with all data accessible to researchers worldwide. It currently in the process of bringing back 100,000 original participants for brain, heart and body MRI, carotid ultrasound low-dose bone/fat x-ray. The brain imaging component covers 6 modalities (T1, T2 FLAIR, susceptibility weighted Resting fMRI, Task fMRI Diffusion MRI). Raw processed from first 10,000 imaged subjects has recently been released general research...
ABSTRACT The Lower Cretaceous (Albian) upper Blairmore Group is part of a thick clastic wedge that formed adjacent to the rising Cordillera in south‐western Alberta. Regional transgressive intervals are superimposed on overall regressive succession. Alluvial conglomerates, sandstones and mudstones were deposited east‐north‐eastward draining fluvial systems, orientated transverse basin axis. Five facies associations have been identified: igneous pebble conglomerate, sandstone, interbedded...
Abstract We present MMORF—FSL’s MultiMOdal Registration Framework—a newly released nonlinear image registration tool designed primarily for application to magnetic resonance imaging (MRI) images of the brain. MMORF is capable simultaneously optimising both displacement and rotational transformations within a single framework by leveraging rich information from multiple scalar tensor modalities. The regularisation employed in promotes local rigidity deformation, we have previously...
ABSTRACT Two partial theropod braincases recovered from the Upper Cretaceous Prince Creek Formation confirm presence of Troodon formosus in Alaska. Characters that distinguish one specimen as include; a very strongly developed sagittal crest on fused parietals, details pneumatic spaces within skull bones, and size location nervous venous foramina. The second has distinct lateral depression diagnostic troodontid braincase. recovery these specimens, coupled with absence non-dental material...