A5081073600- Orthopaedic implants and arthroplasty
- Intensive Care Unit Cognitive Disorders
- Total Knee Arthroplasty Outcomes
- Orthopedic Infections and Treatments
- Anesthesia and Neurotoxicity Research
- Osteoarthritis Treatment and Mechanisms
- Bone Tissue Engineering Materials
- Bone fractures and treatments
- Electrolyte and hormonal disorders
- Venous Thromboembolism Diagnosis and Management
- Metallic Glasses and Amorphous Alloys
- Shoulder Injury and Treatment
- Foot and Ankle Surgery
- Diabetic Foot Ulcer Assessment and Management
- Dental materials and restorations
- Pelvic and Acetabular Injuries
- Blood transfusion and management
- Hip and Femur Fractures
- Antioxidant Activity and Oxidative Stress
- Cell Adhesion Molecules Research
- Orthopedic Surgery and Rehabilitation
- Acute Myocardial Infarction Research
- Titanium Alloys Microstructure and Properties
- High Entropy Alloys Studies
- Knee injuries and reconstruction techniques
Chulalongkorn University
2014-2025
Thai Red Cross Society
2011-2024
King Chulalongkorn Memorial Hospital
2011-2024
University of Iowa Hospitals and Clinics
2015
University of Iowa
2014
Background and objective An ultrasound-guided anesthetic technique targeting the interspace between popliteal artery capsule of posterior knee (iPACK) can provide analgesia with preserved motor function after total arthroplasty (TKA). This study compared peroneal nerve motor-sparing effects iPACK block tibial (TNB) when combined local infiltration (LIA) continuous adductor canal (CACB). Methods In this study, 105 patients scheduled for elective TKA were randomized to receive proximal...
Osteoarthritis (OA) is a common degenerative joint disease causing pain, stiffness, reduced motion, swelling, crepitus, and disability. Dickkopf-1 (Dkk-1) critical mediator of osteoblastogenesis regulates the remodeling. The aim this study was to examine plasma synovial fluid Dkk-1 levels patients with primary knee OA investigate their relationship severity.Thirty-five aged 55-83 years 15 healthy individuals were recruited into study. Disease severity determined using weight-bearing...
Osteoarthritis (OA) is a chronic progressive degenerative joint disorder which characterised by strongly age-related regressive changes in articular cartilage. The objective of this study was to evaluate oxidative stress and antioxidant parameters plasma synovial fluid patients with primary knee osteoarthritis.Thirty-five OA 35 healthy controls were recruited for study. Nitrite, malondialdehyde (MDA), vitamin E, Trolox Equivalent Antioxidant Capacity (TEAC), Ferric Reducing Power (FRAP)...
Abstract Background The objectives of this study were to delineate whether delirium in older adults is associated with activation the immune-inflammatory response system (IRS) as indicated by M1, T helper (Th)1, and Th17 profiles, and/or reduced activities compensatory immunoregulatory (CIRS), including Th2 regulatory profiles. Methods We recruited 65 adult patients a low energy impact hip fracture who underwent operation. CAM-ICU Delirium Rating Scale, Revised-98-Thai version (DRS-R-98)...
Abstract This study aimed to synthesize, characterize, and evaluate the adhesion strength of titania nanotubes (titania nanotubes) iodine‐doped (I‐titania architectures on additively manufactured Ti‐6Al‐4 V (Ti64) implant surface. The I‐titania were synthesized through two stages electrochemical anodization, whereby are anodically fabricated a conventional approach then modified by replacing ethylene glycol electrolyte with potassium iodide solution. characterization results revealed...
Extensile open approaches to reduce and fix intra-articular calcaneal fractures are associated with high levels of wound complications. To avoid these complications, a technique percutaneous reduction fixation screws alone was developed. This study assessed the clinical outcomes, radiographs, postoperative CT scans after operative treatment this technique.153 consecutive patients 182 were reviewed. All for early complications at 3 months from injury. The results seen minimum 1 year surgery...
This work aimed to develop new antibiotic-coated/ antibiotic-loaded hydroxyapatite (HAp) scaffolds for orthopaedic trauma, specifically treat the infection after fixation of skeletal fracture. The HAp were fabricated from Nile tilapia (Oreochromis niloticus) bones and fully characterized. coated with 12 formulations poly (lactic-co-glycolic acid) (PLGA) or (lactic (PLA), blended vancomycin. vancomycin release, surface morphology, antibacterial properties, cytocompatibility conducted. powder...
This study was performed to evaluate the antioxidative and anti-inflammatory effects of vitamin E on oxidative stress in plasma, synovial fluid, tissue patients with knee osteoarthritis. Seventy-two late-stage osteoarthritis scheduled for total arthroplasty were randomized take oral placebo (Group A) or 400 IU B) once a day 2 months before undergoing surgery. The blood levels endpoints indicating antioxidant capacity, Knee Society Score (KSS), Western Ontario McMaster Universities...
Postoperative delirium in elderly people with hip fracture is associated various adverse clinical outcomes. Nevertheless, the pathophysiological processes underpinning have remained elusive.The aim of this study was to explore associations between and its features immune-inflammatory blood gas biomarkers.In prospective study, we examined 65 patients who underwent a surgery assessed Confusion Assessment Method for Intensive Care Unit, Richmond Agitation-Sedation Scale (RASS), Delirium Rating...
Ti based amorphous alloy exhibits excellent properties for biomedical applications. In general, it has high strength, low elastic modulus, good corrosion resistance and satisfactory biocompatibility. This work reported on a systematic study of novel Ti44Zr10Pd10Cu6Co23Ta7, Ti44Zr10Pd10Cu10Co19Ta7 Ti44Zr10Pd10Cu14Co15Ta7 metallic glass. Cylindrical rod samples with diameter 5 mm 20 length were fabricated by induction melting casting into copper mold. The cast was then used as plasma cathode...
Introduction Delirium is accompanied by immune response system activation, which may, in theory, cause a breakdown of the gut barrier and blood–brain (BBB). Some results suggest that BBB compromised delirium, but there no data regarding barrier. This study investigates whether delirium associated with impaired barriers elderly adults undergoing hip fracture surgery. Methods We recruited 59 older measured peak Rating Scale (DRS) scores 2–3 days after surgery, assessed plasma IgG/IgA levels...
Background: Connective tissue growth factor (CTGF) has been implicated in development of osteoarthritis (OA).Objective: To determine the correlation between plasma and synovial fluid CTGF levels severity knee patients.Methods: A total 100 subjects were recruited into this study (75 OA patients 25 controls). concentrations analyzed by enzyme-linked immunosorbent assay.Results: Plasma correlated with radiographic severity. There was a positive levels.Conclusion: could be useful for monitoring...
The aim of this study is to synthesize Titania nanotubes (TNTs) on the 3D-printed Ti-6Al-4V surface and investigate loading antibacterial vancomycin drug dose 200 ppm for local treatment application 24 h. release from synthesized evaluated via chemical measurement linear fitting Korsmeyer-Peppas model was also assessed. TNTs were through anodization process at different time. morphology characterized using field emission scanning electron microscope (FESEM). wettability composition assessed...
Zoledronic acid has been used for prevention of osteolytic and osteoblastic bone metastasis. This case report illustrates an undesirable consequence from prolonged usage zoledronic in metastasis prevention. Periprosthetic acetabular fracture a patient treated with 7 years was reported. The clinical presentation, radiographic pathological results were described. is rare complication after total hip arthroplasty which should not be ignored especially patients who received long term bisphosphonate.