A5101839275- Pleural and Pulmonary Diseases
- Neurofibromatosis and Schwannoma Cases
- Glioma Diagnosis and Treatment
- Cancer-related Molecular Pathways
- Meningioma and schwannoma management
- Head and Neck Surgical Oncology
- Occupational and environmental lung diseases
- Spinal Fractures and Fixation Techniques
- Galectins and Cancer Biology
- Organ Transplantation Techniques and Outcomes
- Soft tissue tumor case studies
- Fungal Infections and Studies
- Gestational Trophoblastic Disease Studies
- Restraint-Related Deaths
- Zebrafish Biomedical Research Applications
- Nerve Injury and Rehabilitation
- Cardiovascular Effects of Exercise
- Ubiquitin and proteasome pathways
- Congenital Diaphragmatic Hernia Studies
- Long-Term Effects of COVID-19
- Cardiac Health and Mental Health
- Traumatic Ocular and Foreign Body Injuries
- Hemophilia Treatment and Research
- RNA modifications and cancer
- Cancer Immunotherapy and Biomarkers
Tongji Hospital
2025
Huazhong University of Science and Technology
2025
Guangdong Academy of Medical Sciences
2011-2022
Guangdong Provincial People's Hospital
2022
Guangzhou University of Chinese Medicine
2021
People's Hospital of Bishan District
2021
Southwest Hospital
2020
Tianjin Medical University
2020
Army Medical University
2020
Qinghai No.3 People's Hospital
2019
Rationale: Tumor cells possess sophisticated strategies to circumvent immune detection, including the modulation of endogenous checkpoints, particularly those within B7 family. Elucidating mechanisms that govern induction family molecules is crucial for advancement immunotherapy. Lysine lactylation (Kla), a newly identified epigenetic modification, suggested may play role in reshaping tumor microenvironment and facilitating evasion. Methods: We analyzed glycolysis pathway's enrichment...
High-intensity interval training (HIIT) is an emerging method of cardiac rehabilitation, which more and popular in recent years. Research into the effect HIIT on peak oxygen uptake (VO2 peak) myocardial fibrosis among patients with infarction (MI) lacking. Here, we describe rationale along protocol for a clinical trial to test following hypotheses: (1) compared control group, VO2 will be increased both moderate-intensity continuous (MICT) groups (2) due MI improved by MICT.This...
In recent years, there is a growing incidence of granulomatous lobular mastitis (GLM), but studies about the coexistence erythema nodosum (EN) and GLM are rare. this study, we assess clinical characteristics predictive factors EN in GLM.A total 303 patients diagnosed with were enrolled from January 2012 to October 2018 at second affiliated Hospital Guangzhou University Traditional Chinese Medicine, including 78 EN. Follow-up data included: lesion site, size, therapy approaches, course GLM,...
Cystic echinococcosis (CE) is a common, chronic, and endemic zoonotic disease usually localized in single organ; multivisceral cases are rare, especially outside the liver or lung. Here, we describe an unusual case of 43-year-old Tibetan man with infratemporal fossa, heart, liver, pancreas, abdomen, pelvic cavity. He only presented diminished vision left eye, when chewing. Computed tomography magnetic resonance imaging revealed CE. The patient underwent surgery for excision cyst as well...
Abstract Objectives To investigated the relationship between neutrophil-to-lymphocyte ratio (NLR) and severity of lung injury in corona virus disease 2019 (COVID-19) patients.Methods The clinical data, laboratory examination, chest computed tomography (CT) findings 167 patients with confirmed COVID-19 admitted to 5 hospitals Chongqing, China from January 2020 February were retrospectively reviewed. According diagnostic criteria sixth edition “Diagnosis Treatment New Coronavirus Pneumonitis”...
Pulmonary sequestration (PS) associated with massive hemoptysis, hemothorax, and elevated tumor markers or even lung malignancy has been reported in several studies. These clinical features combined lesions on chest imaging are sometimes hard to differentiate from malignancies often complicate the diagnostic procedure.A 45-year-old man PS presented extremely carcinoembryonic antigen (CEA) pleural effusion was initially misdiagnosed advanced carcinoma, but ultimately diagnosed Aspergillus...
Objective To explore the application of electronic bronchoscope replacing medical thoracoscopy in diagnosis undiagnosed pleural effusion.Methods The diagnostic results and complications 52 patients with unknown reason effusions were retrospectively analyzed,the change under was observed,and pathological examination suspicious tissue carried out.Results In effusion,48 cases confirmed four not by thoracoscopy.The rate 92.31％.Conclusions Electronic etiological effusion is a checking method easy...
Objective To investigate the individualized treatment for traumatic liver rupture. Methods Clinical data of 58 patients with rupture diagnosed and treated in CAPF Sichuan Provincial Corps Hospital between April 2011 December 2013 were retrospectively studied. The informed consents all obtained local ethical committee approval had been received. Among patients, 31 males 27 females age ranging from 2 to 76 years old median 44 old. According American Association Surgery Trauma (AAST)...
Objective To investigate the clinical features and surgical outcomes of pediatric spinal meningiomas in order to provide evidence for diagnosis treatment. Methods The data 12 children (≤15 ys) with admitted Department Neurosurgery, Beijing Tiantan Hospital from January 2008 December 2015 were analyzed retrospectively. The lateral position was used all patients tumors resected under microscope by posterior midline approach. Among them, 7 underwent laminectomy remaining 5 received...
Objective To explore the CT and MR imaging features of nodular fasciitis(NF), which will in return improve standard quality diagnosis. Methods (n = 4) MRI 5) findings pathologically proved fasciitis 9 patients were retrospectively analyzed. Results Of NF, 5 located lower extremities, 2 abdominal wall, others acoustic duct. The resected tumor size vary from 1.1 to 9. cm largest diameter mean (3.7±0.3) cm. All lesions appeared as a discrete solid mass on imaging. value was similar muscle....
Objective To discuss the factors affecting prognosis of olecroanon fractures. Methods From January 2004 to 2008, 30 fractures were treated with open reduction and internal fixation. Their mean follow-up time was 26.4 months. A retrospective study done analyze efficacy their treatments. Results All patients cured evaluated by Broberg & Morrey elbow performance score. Nineteen cases rated as excellent, 11 good, 1 fair. The total excellent good rate 96.7%. influencing found include operation...
Objective To discuss the mechanism,major complications,surgical treatment strategies of penetrating stab injury brain.Methods Three cases to brain were analyzed.The relevant literatures reviewed.Results In cases,the sites skull uncommon. case one, tool damaged anterior cerebral artery and hypothalamus, caused cerebrospinal rhinorrhea intracranial infection.There venous sinus injuries in other two cases.After operation,the three patients had favorable outcome.Conclusions Stab could occur any...
Abstract Objectives: Immune regulation mechanism of how Helicobacter pylori urease disrupting the homeostasis host cells remains unknown. Methods: We thus detected effect UreB on macrophage PD-L1 expression with recombinant protein and defective strains. The influence induced CD8 + T cells’ proliferation perforin granzyme were assessed through co-culture model. Results: Urease subset B (UreB) significantly promoted in Bone marrow-derived macrophages (BMDMs) blocked activity H. -primed cells....
Abstract Background Pulmonary fibrosis initiates a pneumonic cascade that leads to the dysfunction of fibroblasts characterized by excess proliferation. Anoikis is physiological process ensures tissue development and homeostasis. Whether disruption anoikis involved in pulmonary remains unclear. Results Here, we investigated mechanism which silica induces fibroblast activation via resistance subsequent fibrosis. lung fibroblasts, alveolar epithelial cells endothelial during was detected...