A5035224916- Plant Molecular Biology Research
- Plant Genetic and Mutation Studies
- Plant Reproductive Biology
- Chromosomal and Genetic Variations
- Plant Virus Research Studies
- Research in Cotton Cultivation
- Polysaccharides Composition and Applications
- Soil Carbon and Nitrogen Dynamics
- Reproductive Biology and Fertility
- Plant and Fungal Interactions Research
- Botanical Research and Applications
- Ubiquitin and proteasome pathways
- Fire effects on ecosystems
- Ginkgo biloba and Cashew Applications
- Quality and Safety in Healthcare
- Cancer-related molecular mechanisms research
- Health, psychology, and well-being
- Hand Gesture Recognition Systems
- Histone Deacetylase Inhibitors Research
- Endoplasmic Reticulum Stress and Disease
- Forest Ecology and Biodiversity Studies
- Corneal Surgery and Treatments
- Colorectal Cancer Surgical Treatments
- Polyomavirus and related diseases
- Stoma care and complications
Shanghai East Hospital
2025
West China Hospital of Sichuan University
2025
Hohai University
2025
Sun Yat-sen University
2021-2024
Sixth Affiliated Hospital of Sun Yat-sen University
2024
Zhejiang University
2022-2024
Chinese Academy of Agricultural Sciences
2023
Institute of Plant Protection
2023
ZheJiang Academy of Agricultural Sciences
2023
Jilin Agricultural University
2022
Structural variations (SVs) have long been described as being involved in the origin, adaption, and domestication of species. However, underlying genetic genomic mechanisms are poorly understood. Here, we report a high-quality genome assembly Gossypium barbadense acc. Tanguis, landrace that is closely related to formation extra-long-staple (ELS) cultivated cotton. An SV-based pan-genome (Pan-SV) was then constructed using total 182 593 non-redundant SVs, including 2236 inversions, 97 398...
Abstract The cereal endosperm is a major factor determining seed size and shape. However, the molecular mechanisms of development are not fully understood. Long noncoding RNAs (lncRNAs) function in various biological processes. Here we show lncRNA, MISSEN , that plays an essential role early rice ( Oryza sativa ). parent-of-origin lncRNA expressed endosperm, negatively regulates development, leading to prominent dent bulge seed. Mechanistically, functions through hijacking helicase family...
Long noncoding RNA (lncRNA) can regulate various physiological and pathological processes through multiple molecular mechanisms in cis trans. However, the role of lncRNAs cardiac hypertrophy is yet to be fully elucidated. A mouse lncRNA microarray was used identify differentially expressed hearts following transverse aortic constriction-induced pressure overload comparing sham-operated samples. The direct impact one lncRNA, Ahit, on cardiomyocyte characterized neonatal rat cardiomyocytes...
The WRKY transcription factors are unique regulatory proteins in plants, which important the stress responses of plants. In this study, 113 genes were identified from apple genome GDDH13 and a comprehensive analysis was performed, including chromosome mapping, phylogenetic, motif collinearity analysis. MdWRKYs expressed different tissues, such as seeds, flowers, stems leaves. We analyzed seven groups found that all them localized nucleus. Among MdWRKYs, MdWRKY70L induced by both drought salt...
The incidence rate of colorectal cancer (CRC) is rising among adults under the age 50 (early-onset cancer, EOCRC). Post-ostomy dysfunction, along with negative perceptions due to incorrect public views and a decline in quality life, has significant impact on these individuals, their families, social relationships. By understanding adaptation process post-ostomy EOCRC(POEOCRC) patients, this study aims provide information for developing targeted nursing interventions population. Based...
Depression and diet are both common modifiable factors related to mortality rates among individuals with cancer, but their combined effects remained underexplored. We aimed comprehensively evaluate the independent joint association of depressive symptoms dietary patterns cancer survivors. A cohort US survivors (3,011 eligible participants, representing 20 million patients) were collected from National Health Nutrition Examination Survey (NHANES) between 2005 2018. Depressive assessed Patient...
Abstract Background Plants have the remarkable ability to generate callus, a pluripotent cell mass that acquires competence for subsequent tissue regeneration. Global chromatin remodeling is required this fate transition, but how process regulated not fully understood. Chromatin-enriched noncoding RNAs (cheRNAs) are thought play important roles in maintaining state. However, whether cheRNAs participate somatic regeneration plants has yet been clarified. Results To uncover characteristics and...
Allotetraploid upland cotton (Gossypium hirsutum L.) is native to the Mesoamerican and Caribbean regions, had been improved in southern United States by mid-eighteenth century, was then dispersed worldwide. However, a Hainan Island Native Cotton (HIC) has long grown extensively on Island, China.
Myeloid cell leukaemia 1 (MCL1) is a pro-survival Bcl-2 family protein that plays important roles in survival, proliferation, differentiation and tumourigenesis. MCL1 fast-turnover degraded via an ubiquitination/proteasome-dependent mechanism. Although several E3 ligases have been discovered to promote the ubiquitination of MCL1, deubiquitinating enzyme (DUB) regulates its stability requires further investigation.The immunoprecipitation was used determine interaction between OTUD1 MCL1. The...
Verticillium , representing one of the world’s major pathogens, causes wilt in important woody species, ornamentals, agricultural, etc., consequently resulting a serious decline production and quality, especially cotton. Gossupium hirutum Gossypium barbadense are two kinds widely cultivated cotton species that suffer from wilt, while G. has much higher resistance toward it than hirsutum . However, molecular mechanism regarding their divergence remains largely unknown. In current study, cv....
Abstract MEIOSIS ARRESTED AT LEPTOTENE1 (MEL1), a rice (Oryza sativa) Argonaute (AGO) protein, has been reported to function specifically at premeiotic and meiotic stages of germ cell development is associated with novel class cell-specific small noncoding RNAs called phased (phasiRNAs). MEL1 accumulation temporally spatially regulated eliminated after meiosis. However, the metabolism turnover (i.e. homeostasis) during remains unknown. Here, we show that ubiquitinated subsequently degraded...
Neoadjuvant therapy for locally advanced colorectal cancer has made great progress in the past 20 years, but there are still limitations such as side effects, organ dysfunction and unsatisfactory control of metastasis. In recent with improvement surgical techniques further development molecular research, how to improve local control, reduce distant metastasis, even avoid surgery according clinical remission achieve preservation, is current demand research goal. With advancement different...
Introduction Aphids form a stable and mutually beneficial relationship with their primary symbiont Buchnera aphidicola , which play an important role in providing the missing nutrients to host aphid. Based on genome sequence of wheat aphid Siotobion miscanthi its that we obtained our previously study, identified metabolic relay gene, ilvA involved isoleucine synthesis pathway between aphids . Method In this location structure gene genome, expression level different instars tissues aphids,...
Merkel cell carcinoma (MCC) is a rare primary cutaneous neoplasm of neuroendocrine the skin. About 80% MCC occurs due to polyomavirus (MCPyV) and 20% tumors usually occur severe UV exposure which more aggressive type MCC. It tends have an increased incidence rate among elderly immunosuppressed individuals. On therapeutic level, sub-classification through molecular subtyping has emerged as promising technique for prognosis. In current study, two consistent distinct subtypes MCCs were...
Heterosis has revolutionized crop breeding, enhancing global agricultural production. However, the mechanisms underlying heterosis remain obscure. Xiangzamian 2# (XZM2), a super hybrid upland cotton (Gossypium hirsutum L.) characterized by high-yield heterosis, been developed and extensively planted in China. We conducted systematic analysis of CRI12 J8891, two parents XZM2. aimed to reveal precise genetic information role non-syntenic divergence shaping laying foundation for advancing...
Although the application of heterosis has significantly increased crop yield over past century, mechanisms underlying this phenomenon still remain obscure. Here, we applied transcriptome sequencing to unravel impacts parental expression differences and transcriptomic reprogramming in cotton heterosis.