A5053484598- Malaria Research and Control
- Mosquito-borne diseases and control
- HIV Research and Treatment
- Bird parasitology and diseases
- Hepatitis B Virus Studies
- Digital Imaging for Blood Diseases
- Vector-borne infectious diseases
Emory University
2017-2024
Emory and Henry College
2019
Emory National Primate Research Center
2019
Kra monkeys (Macaca fascicularis), a natural host of Plasmodium knowlesi, control parasitaemia caused by this parasite species and escape death without treatment. Knowledge the disease progression resilience in kra will aid effective use to study mechanisms malaria. This longitudinal aimed define clinical, physiological pathological changes infected with P. which could explain their resilient phenotype.
Plasmodium vivax can cause severe malaria with multisystem organ dysfunction and death. Clinical reports suggest that parasite accumulation in tissues may contribute to pathogenesis disease severity, but direct evidence is scarce. We present quantitative parasitological histopathological analyses of tissue sections from a cohort naive, mostly splenectomized Saimiri boliviensis infected P define the relationship load histopathology. The lung, liver, kidney showed most injury, pathological...
Plasmodium knowlesi poses a health threat throughout Southeast Asian communities and currently causes most cases of malaria in Malaysia. This zoonotic parasite species has been studied Macaca mulatta (rhesus monkeys) as model for severe malarial infections, chronicity, antigenic variation. The phenomenon variation was first recognized during rhesus monkey infections. -encoded variant proteins were discovered this found to be expressed at the surface infected erythrocytes, then named...
Abstract Plasmodium cynomolgi causes zoonotic malarial infections in Southeast Asia and this parasite species is important as a model for vivax ovale . Each of these produces hypnozoites the liver, which can cause relapsing blood. Here we present methods data generated from iterative longitudinal systems biology infection experiments designed performed by Malaria Host-Pathogen Interaction Center (MaHPIC) to delve deeper into biology, pathogenesis, immune responses P. Macaca mulatta host....
ABSTRACT Background Kra monkeys ( Macaca fascicularis ), a natural host of Plasmodium knowlesi, control parasitaemia caused by this parasite species and escape death without treatment. Knowledge the disease progression resilience in kra will aid effective use to study mechanisms malaria. This longitudinal aimed define clinical, physiological pathological changes infected with P. which could explain their resilient phenotype. Methods n = 15, male, young adults) were intravenously...