A5041811639- Crystallization and Solubility Studies
- X-ray Diffraction in Crystallography
- Click Chemistry and Applications
- Catalytic C–H Functionalization Methods
- Synthesis and Biological Evaluation
- Chemical Synthesis and Analysis
- Drug Solubulity and Delivery Systems
- Pharmacological Effects of Medicinal Plants
- Phytochemical compounds biological activities
- Microtubule and mitosis dynamics
- Toxin Mechanisms and Immunotoxins
- Fungal Plant Pathogen Control
- Natural product bioactivities and synthesis
- Cyclopropane Reaction Mechanisms
- Synthesis and Reactions of Organic Compounds
- Computational Drug Discovery Methods
- Surface Chemistry and Catalysis
- Nanoparticle-Based Drug Delivery
- Synthesis and Reactivity of Heterocycles
- Asymmetric Synthesis and Catalysis
- Force Microscopy Techniques and Applications
- Advanced Drug Delivery Systems
- Sesquiterpenes and Asteraceae Studies
Central Institute of Medicinal and Aromatic Plants
2021-2024
Academy of Scientific and Innovative Research
2021-2024
Liposomes are most placed acquiring in pharma industries and very useful the various drug delivery system used to target particular tissue. Because of structural similarity between lipid bilayer (two layer) cell membrane, liposome can easily penetrate effectively deliver such that a free would not penetrate. be also encapsulate both hydrophilic hydrophobic materials, utilized as carriers delivery. This technology is for treatment certain diseases. Now day's researcher attraction interest...
Present study aimed at a single component cyclization of 2-benzylidene-1-tetralones for the preparation 5H-benzo[c]fluorenes and their antiproliferative activity. This ring closure reaction underwent via reductive in presence aluminium chloride-sodium borohydride system. Ten diverse 5H-benzo[c]fluorene derivatives were prepared evaluated activity against three human cancer cell lines by SRB assay. Four these benzofluorenes exhibited significant effect with IC50 >10.75µM. The best...
Heterocyclic compounds have a prominent role in medicinal chemistry and drug design. They are not only useful as medicinally active but also modular structural scaffold for Therefore, heterocycles present many ligands that exhibit broad spectrum of biological activities. Pyazolopyrimidines nitrogen part biologically marketed drugs. This study examines the non-covalent interactions between pyrazolopyrimidine rings receptor proteins through data mining analysis high-resolution crystal...
1,8-Diazabicyclo[5.4.0]undec-7-en (DBU) mediated synthesis of α-benzylated 1-indanones via DBU/enolate and DBU/benzyl bromide organocycles under mild reaction conditions.
The crystal structure of the heterocyclic compound 2-(4-methoxyphenyl)-7-phenylpyrazolo[1,5- c ]pyrimidine, C 19 H 15 N 3 O, has been determined and its self-assembly on surface graphite examined using atomic force microscopy (AFM). title crystallized in monoclinic space group P 2 1 / , with two independent molecules asymmetric unit. packing L-shaped is governed by arene interactions, absence any conventional hydrogen-bonding interactions. arrangement reveals four types dimeric motifs...