A5048727739- Atrial Fibrillation Management and Outcomes
- Cardiac Arrhythmias and Treatments
- Acute Myocardial Infarction Research
- Cardiovascular Function and Risk Factors
- Health Systems, Economic Evaluations, Quality of Life
- Lipoproteins and Cardiovascular Health
- Cardiac Health and Mental Health
- Bioinformatics and Genomic Networks
- GDF15 and Related Biomarkers
- Antiplatelet Therapy and Cardiovascular Diseases
- Cardiac Imaging and Diagnostics
- Genetic Associations and Epidemiology
- Cardiovascular Effects of Exercise
- Acute Ischemic Stroke Management
- Hemodynamic Monitoring and Therapy
German Centre for Cardiovascular Research
2022-2024
Universität Hamburg
2019-2024
University Medical Center Hamburg-Eppendorf
2019-2024
University Cancer Center Hamburg
2022-2023
Martini-Klinik
2020
Background Atrial fibrillation (AF) and atrial flutter (AFL) are common conditions that can lead to significant morbidity death. We aimed understand the distribution disparities of global burden AF/AFL as well underlying risk factors. Methods Results Data on from Global Burden Disease data set were analyzed for years 1990 2019, with countries grouped into low, lower-middle, upper-middle, high national income classes according World Bank categories. supplemented Health Organization...
Abstract Aims Classical cardiovascular risk factors (CVRFs), biomarkers, and common genetic variation have been suggested for assessment of atrial fibrillation (AF). To evaluate their clinical potential, we analysed individual combined ability AF prediction. Methods results In N = 6945 individuals the FINRISK 1997 cohort, assessed predictive value CVRF, N-terminal pro B-type natriuretic peptide (NT-proBNP), 145 recently identified single-nucleotide polymorphisms (SNPs) in a developed...
Background and Aims The relationship between postoperative atrial fibrillation (POAF) 25-hydroxyvitamin D [25(OH)D] concentration as well vitamin supplementation has been discussed controversially. relation of pre-operative status POAF remains unclear. Methods Results We analysed the risk in a prospective, observational cohort study n = 201 patients undergoing coronary artery bypass graft surgery (CABG) with 25(OH)D concentration. median age was 66.6 years, 15.4% were women. (25th/75th...
Abstract Background Atrial fibrillation is associated with cognitive dysfunction. cardiomyopathy has been correlated both entities. We aimed to characterize the association of echocardiographic parameters atrial function and cerebral changes. Methods Participants population-based Hamburg City Health Study underwent in-depth transthoracic echocardiography testing, Animal Naming Test (ANT), Trail Making A (TMT-A) B (TMT-B), 10-word learning test magnetic resonance imaging. Results After...
Abstract Introduction Experimental biomarkers including Angiopoietin-2 (ANG2), bone morphogenetic protein 10 (BMP10), fibroblast growth factor 23 (FGF23), and insulin-like factor-binding 7 (IGFBP7) are hypothesized to reflect cardiac pathophysiological processes that potentially present in adverse remodeling volume or pressure overload. This study aims elucidate the relationship between these circulating presence of hemodynamically significant overload outcomes compare it N-terminal pro...
Abstract Funding Acknowledgements Type of funding sources: Public grant(s) – EU funding. Main source(s): H2020-SC1-BHC-30-2019- 847770 Background Disease awareness is key for the uptake preventive measures and positively affects self-management atrial fibrillation patients (AF pat) or those at increased risk AF. Less evidence exists about pat subjective awareness. We aims to identify predictors incorrect estimation guide future information AF stakeholders. Method In a prospective cardiology...
Abstract Background Classical cardiovascular risk factors (CVRF), biomarkers and genetic variation have been suggested for assessment of atrial fibrillation (AF). Purpose To evaluate their clinical potential, we analysed individual combined effectiveness in AF prediction. Methods In N=6945 individuals the FINRISK 1997 cohort, assessed predictive value CVRF, N-terminal pro B-type natriuretic peptide (NT-proBNP) 145 recently identified single nucleotide polymorphisms (SNPs) incident AF....
ZUSAMMENFASSUNG Vorhofflimmern (VHF) ist mit dem Auftreten von ischämischen Schlaganfällen assoziiert. Orale Antikoagulation kann das verhindern. Das Screening auf ein bislang nicht entdecktes VHF erscheint daher vielversprechender Ansatz, um zu Neben zahlreichen anderen wissenschaftlichen Studien liegen seit August 2021 die Ergebnisse 2 klinischen Endpunkten vor, STROKESTOP- und LOOP-Studie. Weitere wissenschaftliche Untersuchungen dieser Fragestellung befinden sich in der Durchführung.