A5091184621- Seaweed-derived Bioactive Compounds
- Polysaccharides and Plant Cell Walls
- Echinoderm biology and ecology
- Gut microbiota and health
- Algal biology and biofuel production
- Phytochemicals and Antioxidant Activities
- Marine Sponges and Natural Products
- Probiotics and Fermented Foods
- Bioactive Compounds and Antitumor Agents
- Photosynthetic Processes and Mechanisms
- Long-Term Effects of COVID-19
- Vitamin C and Antioxidants Research
- COVID-19 and Mental Health
- Biocrusts and Microbial Ecology
- Polysaccharides Composition and Applications
- Fungal Biology and Applications
- Workaholism, burnout, and well-being
- Obsessive-Compulsive Spectrum Disorders
- Protein Hydrolysis and Bioactive Peptides
- Wound Healing and Treatments
- Circadian rhythm and melatonin
- Nanoplatforms for cancer theranostics
- S100 Proteins and Annexins
- Barrier Structure and Function Studies
- Biological Research and Disease Studies
Shantou University
2020-2024
Guangdong Ocean University
2023
Annamalai University
2012-2022
University of Madras
2017-2019
Memorial Sloan Kettering Cancer Center
2017
Periyar University
2015
Salem Hospital
2015
Indian Institute of Technology Madras
2014
The pharmacological values of marine algal polysaccharides on gut health are being recognized in recent research. However, the protective effect degraded from Porphyra haitanensis (PHP-D) colonic mucosal barrier damaged ulcerative colitis is poorly understood. purpose this study was to investigate how PHP-D could maintain integrity layer mediated by microbiota a dextran sulfate sodium (DSS)-induced mouse model. Structural analysis revealed that had typical porphyran structure having backbone...
Porphyra haitanensis, with its rich nutritional value and distinctive flavour, has become a research hotspot in food field. P. haitanensis oligosaccharides (PHO) are potential anti-inflammatory properties that ameliorate lipopolysaccharide-induced inflammatory responses the vitro IEC-6 cell line model. Here, structure of PHO was investigated, LPS–induced injury mechanisms were determined by cellular, molecular, transcriptome analyses. After exposure, LPS-induced cells showed reduced...
Morchella esculenta is an edible mushroom with special flavor and high nutritional value for humans, primarily owing to its polysaccharide constituents. M. polysaccharides (MEPs) possess remarkable pharmaceutical properties, including antioxidant, anti-inflammatory, immunomodulatory, anti-atherogenic activities. The aim of this study was evaluate the in vitro vivo antioxidant potential MEPs. In activity determined using free radical scavenging assays, whereas evaluated through dextran sodium...
Marine macroalgae consist of a range bioactive molecules exhibiting different biological activities, and many these properties are attributed to sulfated polysaccharides, fucoxanthin, phycobiliproteins, halogenated compounds. In this study, glycoprotein (GLP) with molecular mass ∼48 kDa was extracted purified from Codium decorticatum investigated for its cytotoxic against human MDA-MB-231 breast cancer cells. The IC₅₀ values GLP normal HBL-100 cells (control) were 75 ± 0.23 μg/mL (IC₂₅), 55...
Food waste can be used more efficiently to increase food sustainability. Polysaccharides from jackfruit peel (PJP)1 are derived agricultural waste, and little is known about their in vitro digestion fermentation characteristics. This study aimed elucidate PJP structural properties, the dynamic changes during simulated salivary gastrointestinal fecal fermentation, its effects on human intestinal microbiota. Structural analysis showed a typical polysaccharide structure with high stability an...
The aim of this study was to analyze if the 2‐pyrrolidinone rich fraction Brassica oleracea var. capitata exhibiting antioxidant and in vitro anticancer activities. 2‐Pyrrolidinone is an active compound present . Our findings explored potential use cancer treatment. This identified isolated by gas chromatography–mass spectrometry high‐performance liquid chromatography from leaf resultant exhibited cytotoxicity HeLa PC‐3 human cell lines, it also activity free assays. DAPI staining, apoptotic...
Cancer growth and proliferation rely on intracellular iron availability. We studied the effects of Deferiprone (DFP), a chelator iron, three prostate cancer cell lines: murine, metastatic TRAMP-C2; non-metastatic Myc-CaP; human, 22rv1. The DFP were evaluated at different cellular levels: culture migration; metabolism live cells (time-course multi-nuclear magnetic resonance spectroscopy perfusion studies, with 1-13 C-glucose, extracellular flux analysis); expression (Western blot) activity...