Keying Liu

ORCID: 0000-0002-6453-9908
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About
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Research Areas
  • Blind Source Separation Techniques
  • Mathematical and Theoretical Epidemiology and Ecology Models
  • Ethics in Clinical Research
  • Spectroscopy and Chemometric Analyses
  • Advanced Differential Equations and Dynamical Systems
  • Insurance, Mortality, Demography, Risk Management
  • Forest Ecology and Biodiversity Studies
  • Agricultural risk and resilience
  • Fatty Acid Research and Health
  • Microbial Metabolic Engineering and Bioproduction
  • Electromagnetic Scattering and Analysis
  • Lipid metabolism and biosynthesis
  • Prenatal Screening and Diagnostics
  • Nonlinear Differential Equations Analysis
  • Protein Hydrolysis and Bioactive Peptides
  • Microwave Imaging and Scattering Analysis
  • Enzyme Catalysis and Immobilization
  • Electromagnetic Simulation and Numerical Methods
  • Phytochemical compounds biological activities
  • Plant Pathogens and Fungal Diseases
  • Natural product bioactivities and synthesis
  • BRCA gene mutations in cancer
  • Speech and Audio Processing
  • Mycorrhizal Fungi and Plant Interactions
  • Mathematical Biology Tumor Growth

Guangdong Ocean University
2024-2025

Renji Hospital
2024-2025

Shanghai Jiao Tong University
2024-2025

North China University of Water Resources and Electric Power
2010-2025

Dalian Polytechnic University
2024

Key Laboratory of Chemistry for Natural Products of Guizhou Province and Chinese Academy of Sciences
2024

Guiyang Medical University
2024

State Key Laboratory of Oncogene and Related Genes
2024

Shanghai Cancer Institute
2024

Northeast Forestry University
2024

Analyzing genomic data across populations is central to understanding the role of genetic factors in health and disease. Successful sharing relies on public support, which requires attention whether people around world are willing donate their that then subsequently shared with others for research. However, studies such perceptions geographically limited do not enable comparison. This paper presents results from a very large survey attitudes toward sharing. Data 36,268 individuals 22...

10.1016/j.ajhg.2020.08.023 article EN cc-by The American Journal of Human Genetics 2020-09-17

Abstract Background Public trust is central to the collection of genomic and health data sustainability research. To merit trust, those involved in collecting sharing need demonstrate they are trustworthy. However, it unclear what measures most likely this. Methods We analyse ‘Your DNA, Your Say’ online survey public perspectives on including responses from 36,268 individuals across 22 low-, middle- high-income countries, gathered 15 languages. examine how participants perceived relative...

10.1186/s13073-021-00903-0 article EN cc-by Genome Medicine 2021-05-25

Porphyra haitanensis, a red seaweed species, represents bountiful and sustainable marine resource. P. haitanensis polysaccharide (PHP), has garnered considerable attention for its numerous health benefits. However, the comprehensive utilization of PHP on an industrial scale been limited by lack information. In this review, we endeavor to discuss summarize recent advancements in extraction, purification, characterization. We emphasize multifaceted mechanisms through which promotes...

10.1016/j.fochx.2024.101414 article EN cc-by-nc Food Chemistry X 2024-04-26

Abstract A large number of empirical studies have shown that regime switching is an important characteristic temperature processes. Thus, this work develops efficient finite difference scheme with one-sided to price weather derivatives the partial differential equations (PDEs) regime-switching models. For management purposes, initial model framework then proposed manage portfolios incorporating derivatives. This also performs statistical analysis on dataset from Toronto, Canada and...

10.1093/imaman/dpaf003 article EN IMA Journal of Management Mathematics 2025-02-02

Recent advancements in antibody-drug conjugates (ADCs) targeting trophoblast surface cell antigen 2 (Trop-2) have brought important progress the field of targeted therapy. This also holds promise for treatment small lung cancer (SCLC) as anti-Trop-2 therapy appears to a safe and effective clinical activity metastatic SCLC patients. However, treatments ADCs rely on comprehensive assessment Trop-2 expression at tumor sites, exhibits intratumoral heterogeneity, making accurate acquisition...

10.1186/s12951-025-03184-6 article EN cc-by-nc-nd Journal of Nanobiotechnology 2025-03-06

The ketogenic diet (KD) is a dietary intervention comprising high-fat, low-carbohydrate, and moderate-protein intake designed to induce metabolic state known as ketosis, whereby ketone bodies are produced an alternative source of energy. Initially established treatment for intractable epilepsy, the KD has subsequently gained significant attention its potential manage neurodegenerative diseases, including Alzheimer’s, Parkinson’s, Huntington’s disease. Ketone bodies, such beta-hydroxybutyrate...

10.3390/nu17071268 article EN Nutrients 2025-04-04

Mother-to-child transmission is the major cause of chronic hepatitis B virus (HBV) infection. This double-blind trial tested effect tenofovir disoproxil fumarate (TDF) in preventing vertical transmission. Pregnant women who were HBsAg/HBeAg-positive with a HBV DNA titer ≥ 2×106 IU/mL randomly assigned to control (n = 60) and TDF-treated groups. TDF treatment (oral dose 300 mg/day) was initiated at 24 weeks gestation continued 4 after delivery. The subjects followed up 28 postpartum. effects...

10.1038/s41598-018-33833-w article EN cc-by Scientific Reports 2018-10-15

Abstract Pancreatic cancer is one of the most malignant tumors with highest mortality rates, and it currently lacks effective drugs. Aptamer-drug conjugates (ApDC), as a form nucleic acid drug, show great potential in therapy. However, instability acid-based drugs vivo avascularity pancreatic dense stroma have limited their application. Fortunately, VNP20009, genetically modified strain Salmonella typhimurium , which has preference for anaerobic environments, but toxic specificity, can...

10.1038/s41392-024-01973-3 article EN cc-by Signal Transduction and Targeted Therapy 2024-10-14

We are concerned with a kind of three‐dimensional system rational difference equations, given by Kurbanli (2011). A new expression solution the is presented, and asymptotical behavior described. At same time, we also consider different obtain some results, which expand study such equations method can be applied to other systems.

10.1155/2011/178483 article EN cc-by Discrete Dynamics in Nature and Society 2011-01-01

Lycopene is an important natural red pigment with strong singlet oxygen and peroxide free radical quenching ability. Ethanol directly destroys the epithelial cells of gastric mucosa, causing oxidative damage inflammation. To evaluate effect lycopene on ethanol induced injury, 112 adult male Kunming mice were randomly divided into normal control, injury omeprazole (20 mg/kg) positive experimental groups (at doses 10, 50, 100, 150 mg/kg body weight) in this study. The general pathological...

10.3389/fnut.2021.697879 article EN cc-by Frontiers in Nutrition 2021-08-17

The aim of this study was to determine how attitudes toward the return genomic research results vary internationally.We analyzed "Your DNA, Your Say" online survey public perspectives on data sharing including responses from 36,268 individuals across 22 low-, middle-, and high-income countries, these were gathered in 15 languages. We participants responded when asked whether (RoR) would motivate their decision donate DNA or health data. examined variation countries compared other with those...

10.1016/j.gim.2022.01.002 article EN cc-by Genetics in Medicine 2022-02-03

Enzymatic alcoholysis was performed in an organic medium to synthesize 2-monoacylglycerol (2-MAG) rich arachidonic acid. The results showed that solvent type and water activity (aw) significantly affected the 2-MAG yield. Under optimum conditions, 33.58% produced crude product t-butanol system. Highly pure obtained after two-stage extraction using 85% ethanol aqueous solution hexane at first stage dichloromethane second stage. Isolated used as substrate investigate effect of aw on acyl...

10.3390/foods11203213 article EN cc-by Foods 2022-10-14

Diacylglycerol kinase zeta (DGKZ) participates in cancer progression. Here, the current work aims to identify functional role of DGKZ cervical (CC). expression tissues and paired adjacent normal was assessed using Immunohistochemistry assay. SiHa HeLa cells were transfected with lentivirus plasmids (sh-DGKZ or sh-NC) evaluate effects knockdown on cell proliferation, apoptosis cycle distribution vitro. Furthermore, BALB/c nude mice injected subcutaneously Lentivirus-sh-DGKZ-SiHa...

10.1080/21655979.2021.1918505 article EN Bioengineered 2021-01-01

10.1016/j.cam.2017.07.030 article EN Journal of Computational and Applied Mathematics 2017-08-08

Abstract The relations between stability and accuracy of the operator marching method (OMM) are usually conflicting in waveguides with strong range dependence. To explain this phenomenon, study intends to present an error estimate for OMM dependent waveguides. We utilize “approximation level” measure truncation a various step sizes. Then, is developed analyze performances OMM. Through analysis, we verify following features OMM: (i) it valid apply slowly varying very large sizes; (ii) may...

10.1515/jiip-2015-0069 article EN Journal of Inverse and Ill-Posed Problems 2016-01-14

We are concerned with a three‐dimensional system of rational difference equations nonzero initial values. present solutions the in an explicit way and obtain asymptotical behavior solutions.

10.1155/2012/105496 article EN cc-by Discrete Dynamics in Nature and Society 2012-01-01

Through assuming that nonlinear superposition principles (NLSPs) are embedded in a Lie group, class of 3rd‐order PDEs is derived from general determining equation determine the invariant group. The corresponding NLSPs and transformation to linearize PDE found, hence governing proved C ‐integrable. In end, some applications explained, which shows result has very subtle relations with linearization partial differential equation.

10.1155/2012/346824 article EN cc-by Journal of Applied Mathematics 2012-01-01

Woodpeckers exhibit selectivity when choosing tree cavities for nest development in forest ecosystems, and fungi play a significant important role this ecological process. Therefore, there is complex intricate relationship between the various behaviors of woodpeckers occurrence fungal species. Research into bond was undertaken to provide more information about remarkable relationship. Through process line transect sampling, woodpecker traces were searched for, mist nets set up capture them....

10.3390/jof10060389 article EN cc-by Journal of Fungi 2024-05-29

Blind Signal Processing (BSP) has found great applications for foetal electrocardiogram (FECG) extraction. The purpose of this paper is to brief review the Source Separation (BSS) and Extraction (BSE) models algorithms FECG signal processing. After perspective linear BSS BSE extraction are presented, relationship between given; also advantages shown. Then, state-of-the-art algorithms, such as BCBSE algorithm, semiBSE GABSE reference algorithm robustBSE constructed overviewed. limitations...

10.1504/ijbet.2011.043296 article EN International Journal of Biomedical Engineering and Technology 2011-01-01
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