A5085516029- Chronic Myeloid Leukemia Treatments
- Acute Myeloid Leukemia Research
- Histone Deacetylase Inhibitors Research
- Acute Myocardial Infarction Research
- Gout, Hyperuricemia, Uric Acid
- Inflammatory Biomarkers in Disease Prognosis
- Adipokines, Inflammation, and Metabolic Diseases
- Antiplatelet Therapy and Cardiovascular Diseases
- Coronary Interventions and Diagnostics
- Immunodeficiency and Autoimmune Disorders
- Cardiovascular Function and Risk Factors
- Venous Thromboembolism Diagnosis and Management
- Blood disorders and treatments
- Tumors and Oncological Cases
- Acute Lymphoblastic Leukemia research
- Sarcoma Diagnosis and Treatment
- CAR-T cell therapy research
- Immune Cell Function and Interaction
- Eosinophilic Disorders and Syndromes
- Folate and B Vitamins Research
- Metastasis and carcinoma case studies
- Chronic Lymphocytic Leukemia Research
- Glycogen Storage Diseases and Myoclonus
- Lipoproteins and Cardiovascular Health
- Tuberculosis Research and Epidemiology
Nanfang Hospital
2022-2024
Southern Medical University
2022-2024
Shandong Provincial Hospital
2023-2024
Shandong First Medical University
2023-2024
Chinese Academy of Medical Sciences & Peking Union Medical College
2009-2024
Shandong Academy of Chinese Medicine
2024
Shanghai Clinical Research Center
2024
Anhui Agricultural University
2024
Jinan Central Hospital
2024
Capital Medical University
2021-2023
Renal artery stenosis (RAS) impacts the pathogenesis and control of heart failure (HF) may further contribute to increased cardiovascular morbidity mortality in HF patients. However, long-term effects renal revascularization on outcomes patients are not well studied.The prevalence its all-cause were studied 163 consecutive with systemic hypertension chronic kidney disease (serum creatinine >2 mg/dL) who underwent percutaneous transluminal angioplasty (PTRA) stenting for atherosclerotic RAS....
Limited evidence exists on the combined and mediating effects of systemic inflammation association between insulin resistance cardiovascular events in patients with diabetes chronic coronary syndrome (CCS). This secondary analysis a multicenter prospective cohort included 4419 diabetic CCS patients. Triglyceride–glucose index (TyG) high-sensitivity C-reactive protein (hsCRP) were applied to evaluate inflammation, respectively. The primary endpoint was major adverse cardiac event (MACE)....
Human enterovirus (EV) pathogens cause various contagious diseases such as hand, foot, and mouth disease, encephalitis, myocarditis, acute flaccid myelitis, pneumonia, bronchiolitis, which have become serious health threats. However, except for the EV71 vaccine on market, there are no effective strategies to prevent treat other EV pathogen infections. Therefore, broad-spectrum anti-EV drugs urgently needed. In this study, we demonstrated that FNC, a small nucleoside analog inhibitor has been...
<p>Supplementary Figure S4. Survival outcomes in VA and VAH patients depending on FLT3-ITD mutation.</p>
<p>Supplementary Figure S5. Incorporating HHT to overcome VEN resistance.</p>
<div>AbstractPurpose:<p>We investigated whether homoharringtonine (HHT) added to venetoclax plus azacitidine (VA) could improve outcomes and counteract the negative effects of genetic patterns in patients with relapsed/refractory acute myeloid leukemia (RR-AML).</p>Experimental Design:<p>A multicenter retrospective cohort study response VA HHT (VAH) versus regimens as salvage treatment RR-AML was performed. The endpoints were rates composite complete remission,...
<p>Supplementary Figure S3. Prognostic effect of VA and VAH on OS in genetic subgroups.</p>
<p>Supplementary Figure S2. Treatment response rates by co-mutations.</p>
<p>Supplementary Figure S1. Analysis of pairwise co-mutation and mutual exclusivity in the top 20 most frequently detected gene mutations.</p>
BACKGROUND The full implementation of the national two-child policy has presented significant challenges in ensuring safety pregnant women. AIM To investigate effect cervical balloon fluid volume on maternal processes, and infant outcomes, anxiety during pregnancy. METHODS A total 100 singleton term pregnancies with maturity induction were selected using a lottery method; 50 women included. Cervical balloons used for all participants. In control group, 80 mL was injected into both balloons;...
Abstract Objectives We sought to evaluate the independent predictive value of left main disease (LMD) and/or three‐vessel (LMD/3VD) in acute myocardial infarction (AMI) patients. Background Patients with coronary syndrome resulting from LMD are at highest risk adverse cardiovascular events. Neutrophil lymphocyte ratio (NLR) has been proposed as a marker risk, but prognostic NLR patients LMD/3VD who underwent percutaneous intervention (PCI) is not clearly defined. Methods ( n = 806) admitted...
Objective: We aimed to investigate Th22 cells and their association with Th17 Treg in the etiology of severe preeclampsia (sPE).Methods: Thirty sPE patients 30 healthy pregnant women were recruited this study. The percentages Th17, Th22, regulatory T (Tregs) peripheral blood measured by flow cytometry. ELISA was used measure plasma concentrations interleukin (IL)-17, IL-22, IL-10.Results: IL-17 IL-22 significantly increased along a decreased percentage IL-10 concentration. There positive...
Mother-to-child transmission is the major cause of chronic hepatitis B virus (HBV) infection. This double-blind trial tested effect tenofovir disoproxil fumarate (TDF) in preventing vertical transmission. Pregnant women who were HBsAg/HBeAg-positive with a HBV DNA titer ≥ 2×106 IU/mL randomly assigned to control (n = 60) and TDF-treated groups. TDF treatment (oral dose 300 mg/day) was initiated at 24 weeks gestation continued 4 after delivery. The subjects followed up 28 postpartum. effects...
Abstract Background The objective of this study was to assess patient‐reported outcomes (PROs), including health‐related quality life (HRQoL) and anxiety depression symptoms, identify associated variables in patients with tyrosine kinase inhibitor (TKI)‐resistant chronic myeloid leukemia (CML) chronic‐phase (CP) or accelerated‐phase (AP) who were receiving olverembatinib. Methods Patients multicenter studies invited complete the European Organization for Research Treatment Cancer...
The objective of this article is to investigate the clinical features intestinal pseudo-obstruction (IPO) and/or ureterohydronephrosis in systemic lupus erythematosus (SLE). Sixty-one SLE patients with IPO were analyzed retrospectively. A total 183 cases randomly selected as controls from 3840 inpatients without and during same period. Patients assigned 1 3 groups (SLE ureterohydronephrosis, IPO, ureterohydronephrosis). characteristics, treatments, prognosis compared between groups. There 57...
This study primarily aims to explore the value of combining measurement plasma α-synuclein oligomer levels with enhanced T2 star-weighted angiography (ESWAN) in early diagnosis Parkinson's disease.Sixty patients disease and 30 normal adults, similar ages genders, were enrolled study. Their oligomers measured, ESWAN was performed. The amplitudes, phases R2* values head, body tail ipsilateral contralateral substantia nigra pars compacta (SNc) at side limb severe symptoms or symptoms. receiver...