A5077987650- Lung Cancer Research Studies
- Lung Cancer Diagnosis and Treatment
- Pain Management and Opioid Use
- Lung Cancer Treatments and Mutations
- Neuroendocrine Tumor Research Advances
- Management of metastatic bone disease
- Cancer, Stress, Anesthesia, and Immune Response
- Esophageal Cancer Research and Treatment
- Immune cells in cancer
- Cancer survivorship and care
- Cancer Immunotherapy and Biomarkers
- Glioma Diagnosis and Treatment
- Cancer Cells and Metastasis
- Pediatric Pain Management Techniques
- Pancreatic function and diabetes
- Polyamine Metabolism and Applications
- Sphingolipid Metabolism and Signaling
- Pharmacological Effects and Toxicity Studies
- Phagocytosis and Immune Regulation
- NF-κB Signaling Pathways
- Cancer therapeutics and mechanisms
- Gastric Cancer Management and Outcomes
- Medication Adherence and Compliance
- Cancer Diagnosis and Treatment
- Social Capital and Networks
First Affiliated Hospital of Bengbu Medical College
2023-2025
Changhai Hospital
2024-2025
Second Military Medical University
2024-2025
Tianjin Medical University Cancer Institute and Hospital
2012-2023
Anhui Medical University
2022-2023
National Clinical Research
2016-2019
Huashan Hospital
2019
Fudan University
2019
Weihai Chest Hospital
2018
National Natural Science Foundation of China
2016
KL-regularized policy optimization has become a workhorse in learning-based decision making, while its theoretical understanding is still very limited. Although recent progress been made towards settling the sample complexity of contextual bandits, existing bounds are either $\tilde{O}(\epsilon^{-2})$ under single-policy concentrability or $\tilde{O}(\epsilon^{-1})$ all-policy concentrability. In this paper, we propose \emph{first} algorithm with for offline bandits. Our designed general...
Background This study was designed to introduce the key points about transplantation of lower abdominal flap with vascularized lymph node and evaluate effect breast restoration, reconstruction, lymphatic treat upper limb lymphedema after cancer surgery. Materials Methods The based on retrospective 10 cases postmastectomy during January 2008 March 2011. All patients, aged 36 50 years, have had one-side upper-limb for 3 5 years. Six patients accepted radiotherapy. Four a diagnosis severe...
Abstract Breast cancer patients may initially benefit from cytotoxic chemotherapy but experience treatment resistance and relapse. Chemoresistant breast stem cells (BCSCs) play a pivotal role in recurrence metastasis, however, identification eradication of BCSC population are challenging. Here, an mRNA‐based signature is developed using machine learning strategy to evaluate stemness primary patient samples. Using the signature, critical polyamine anabolism regulation chemotherapy‐induced...
High-dose hypofractionated radiotherapy (HRT) is an important anticancer treatment modality that activates antitumor host immune responses. However, HRT for oligometastases of colorectal cancer (CRC) has shown frustrating results in the clinic. As part evasion, myeloid cells express signal regulatory protein α (SIRPα) to inhibit phagocytosis by phagocytes tumor microenvironment (TME). We postulated SIRPα blockade enhances alleviating inhibitory action on phagocytes. demonstrated was...
Literature is limited on the relationship between opiate analgesics and development of infections in cancer patients. This study aimed to determine whether contribute advancement how infection rates differ among various opiates used for management.From January 2013 October 2014, we analyzed retrospectively 642 consecutive advanced patients who received single types opiates, including morphine, oxycodone, or fentanyl, a combination these drugs, continuously >14 days. Binominal logistic...
To quantify the incidental irradiation dose to esophageal lymph node stations when irradiating T1-4N0M0 thoracic squamous cell carcinoma (ESCC) patients with a of 60 Gy/30f.Thirty-nine medically inoperable ESCC were treated three-dimensional conformal radiation (3DCRT) involved-field (IFI). The clinical target volume (CTV) was re-created using 3-cm margin in proximal and distal direction beyond barium esophagogram, endoscopic examination CT scan defined gross tumor (GTV) 0.5-cm lateral...
Abstract Objective This study aimed to provide support for the extensive application of Distress Thermometer (DT) in advanced cancer inpatients with pain and explored factors associated high DT scores among this population. Methods Advanced patients were recruited from Department Pain Relief Tianjin Cancer Hospital Institute, China. They completed problems list HADS within 48 h after admission. The cutoff score was evaluated against Anxiety Depression Scale (HADS) its sensitivity specificity...
To evaluate the clinical efficacy and safety of simultaneous integrated boost intensity-modulated radiotherapy (SIB-IMRT) for patients with locally advanced non-small-cell lung cancer (LANSCLC).48 LANSCLC treated SIB-IMRT from January 2010 to April 2012 were retrospectively analysed. A radiation dose 45-63 Gy (median dose, 51.58 Gy) was delivered planning target volume (1.8-2.0 daily fractions) simultaneously 55.0-74.2 63 gross tumour (2.00-2.25 fractions). 45 received concurrent/sequential...
Frail and pre-frail older people often need to take medications. However, factors related medication adherence among this population remain unclear, warranting further research. This study aims identify correlates of frail adults.From November 2020 December 2020; a total 4218 community-dwelling residents aged ≥ 60 years were interviewed by cross-sectional survey in China. Data on subjects' general information; adherence; frailty status was obtained via the face-to-face structured...
// Yang Chen 1, * , Weishuai Liu 2, Peng Wang 3 Hailing Hou 1 Ningbo Linlin Gong Youyou Kai Ji 2 Lujun Zhao Ping Department of Radiation Oncology, Tianjin Medical University Cancer Institute and Hospital, National Clinical Research Center Cancer, Key Laboratory Prevention Therapy, 300060, China Pain Management, Research, Peking International Beijing 102206, These authors have contributed equally to this work Correspondence to: Zhao, email: zhaolujun@tjmuch.com Keywords:...
The purpose of this study was to evaluate the clinical efficacy and toxicity simultaneous integrated dose reduction intensity-modulated radiotherapy (SIR-IMRT) applied an elective nodal area patients with limited-stage small-cell lung cancer (LS-SCLC). Between January 2010 March 2013, 52 LS-SCLC that treated SIR-IMRT were retrospectively analyzed. A radiation 54 Gy administered in 30 fractions (1.8 Gy/fraction) planning target volume (PTV). Simultaneously, 60 (2 gross tumor volume....
To identify prevalence and severity of nonpain symptoms to clarify possible influences on each symptom.The study used a descriptive survey design. Chinese version the Edmonton Symptom Assessment System was used. Patients' demographic pain characteristics were collected.The most common reported loss appetite (94.3%) followed by insomnia (93.3%), tiredness (91.6%). Prevalence rates symptom all above 70% except "thinking clearly." varied gender, age, primary cancer, characteristics, especially...
In Brief Context: Pedestrian and bicycle plans support community-level physical activity. North Carolina, pedestrian/bicycle are becoming more prevalent. However, no studies have examined the spatial temporal diffusion of plans. Objectives: This study assessed (a) trends associated with municipal planning from 1974 to 2011 (b) patterns plans, specifically, whether publication a plan in given year was number neighboring municipalities Setting: Carolina 2011. Main Outcome Measures: The main...
This study evaluated the analgesic effect of stereotactic body radiotherapy (SBRT) in combination with celiac plexus block (CPB), relative to SBRT alone, locally advanced pancreatic cancer (LAPC) patients.We reviewed medical records all patients LAPC, who received between 1 January 2017 31 August 2019 at our center. The average numeric rating scale (NRS) ≥3 was used admission. We recorded and worst NRS a 24-hour period, daily narcotic doses before SBRT, followed by weekly for month monthly 3...
Abstract Background: Gastric cancer (GC) is one of the most common malignant tumors. Sphingosine kinase-1 (SPHK1) a member SPHK family proteins,which are involved in pathogenesis various cancers. This study aimed to investigate SPHK1 expression GC tissues, and its effects on migration invasion cell lines. Methods: Bioinformatics predicted prognosis. The was detected by immunohistochemistry. Real-time PCR analysis used detect SPHK1mRNA expression. Cell scratch methods. were Transwell assays....
To investigate the expression level of HNRNP A1 in colorectal cancer (CRC) and its prognostic implications.
To investigate the role of sphingosine kinase-1 (SPHK1) in regulating migration and invasion gastric cancer (GC) cells. TIMER2.0, GEPIA HPA databases were used to SPHK1 expression GC, its association with prognosis patients was analyzed using Kaplan-Meier Plotter database. In 40 clinical GC adjacent tissue samples, MKI67 expressions detected immunohistochemistry, Western blotting, RT-qPCR. Gene enrichment pathway analysis conducted explore biological functions SPHK1. HGC-27 MGC-803 cells,...
Glioblastoma Multiforme (GBM) is the most common primary malignant brain tumor.Median survival usually less than 1 year from time of diagnosis, and even in favorable situations, a majority patients die within 2 years.Standard therapy consists surgical resection, radiotherapy chemotherapy.In this case report, we described 38 y old woman with GBM survived 7 years after series treatments.For patient, tumor was found extensively infiltrate sagittal sinus, surgery unable completely remove tumor,...