A5087756729- Nanomaterials and Printing Technologies
- Hepatitis C virus research
- Hepatitis B Virus Studies
- Graphene research and applications
- Nanopore and Nanochannel Transport Studies
- Gold and Silver Nanoparticles Synthesis and Applications
- Membrane Separation Technologies
- Immunotherapy and Immune Responses
- MXene and MAX Phase Materials
- Advanced Sensor and Energy Harvesting Materials
- Physics of Superconductivity and Magnetism
- MicroRNA in disease regulation
- Viral gastroenteritis research and epidemiology
- Endoplasmic Reticulum Stress and Disease
- Photonic Crystal and Fiber Optics
- Solar Thermal and Photovoltaic Systems
- Advanced Theoretical and Applied Studies in Material Sciences and Geometry
- Advancements in Photolithography Techniques
- RNA Interference and Gene Delivery
- Metal and Thin Film Mechanics
- Material Dynamics and Properties
- Mechanical Failure Analysis and Simulation
- Myeloproliferative Neoplasms: Diagnosis and Treatment
- Zebrafish Biomedical Research Applications
- Phase Change Materials Research
First Affiliated Hospital of Bengbu Medical College
2024
Chinese Academy of Sciences
2011-2024
Shanghai Institute of Ceramics
2024
Putian University
2023
Henan Agricultural University
2022
École Polytechnique Fédérale de Lausanne
2022
Jiangsu University
2021
Institute of Microbiology
2014-2020
University of Chinese Academy of Sciences
2012-2020
ETH Zurich
2016-2019
Conductive patterns with line widths of 5–10 µm are successfully fabricated by utilizing the coffee-ring effect in inkjet printing, resulting transmittance values up to 91.2% visible near-infrared region. This non-lithographic approach broadens range fabrication procedures that can be used create various nanoparticle-based microstructures and electronic devices. As a service our authors readers, this journal provides supporting information supplied authors. Such materials peer reviewed may...
In this study, monodisperse silver nanoparticles were synthesized with a new reduction system consisting of adipoyl hydrazide and dextrose at ambient temperature. By facile rapid approach, high concentration obtained on large scale low protectant/AgNO3 mass ratio which was highly beneficial to cost conductivity. Based the nanoparticles, conductive inks prepared water, ethanol ethylene glycol as solvents, expected be more environmentally friendly. A series electrocircuits fabricated by...
Two-dimensional (2D) subnanometer channels allow unique mass transport promising for molecular sieving. New 2D of MoS2 nanosheets one to understand transmission and separation, unlike the graphene oxide counterpart containing various defects cationic metal contaminants. Membranes from layered platelets show extraordinary stability in an aqueous environment compatibility with polymer filters, both beneficial efficient manufacturing. Sharing gas-tightness unimpeded water vapor permeation a...
Highly reproducible SERS arrays on a large scale were fabricated by direct-writing inkjet printing method.
Persistent inflammation in chronic hepatitis plays a major role the development of hepatocellular carcinoma (HCC). In this study, inflammatory cytokines expressed hepatitis, IL-6 and TNF-α, induced marked decrease microRNA-122 (miR-122) levels, miR-122 expression was downregulated livers B (CHB) patients. The caused upregulation proinflammatory chemokine CCL2. TNF-α suppressed both by directly downregulating transcription factor C/EBPα indirectly upregulating c-myc, which blocks...
Architecture of a DNA-wrapped carbon nanotube (CNT) inspires rational design polymer-wrapped CNT effective for CO2 capture. Polyethyleneimine (PEI) selected as spiral wrapper is modified by insertion spacer molecules loaded with amino groups such siloxanes and purine to enhance the capture performance. A porous adsorbent made packing these functional nanowires (e.g., PEI–purine–CNT) reveals uptake large 3.875 mmol/g. Adsorbent materials from this biomolecule-inspired drop adsorption heat...
Cytotoxic T cells (CTLs) play a key role in the control of Hepatitis B virus (HBV) infection and viral clearance. However, most identified CTL epitopes are derived from HBV genotypes A D, few have been defined C which more prevalent Asia. As core protein (HBc) is conservative immunogenic component, this study we used an overlapping 9-mer peptide pool covering HBc to screen identify specific epitopes. An unconventional HLA-A2-restricted epitope HBc141–149 was discovered structurally...
Programmed death ligand 1 (PD-L1) has been recently shown to be a major obstacle antiviral immunity by binding its receptor programmed (PD-1) on specific IFN-γ producing T cells in chronic hepatitis B. Currently, IFN-α is widely used treat B virus (HBV) infection, but effect vary greatly and the mechanism not totally clear. We found that IFN-α/γ induced marked increase of PD-L1 expression hepatocytes. Signal activators transcription (Stat1) was then identified as factor involved...
Inkjet printing is a non-contact and low-cost method for high resolution deposition of nanomaterials mass production electro-devices. In this study, an environmentally friendly gold nanoparticles (AuNPs) ink was prepared electrochemical electrodes were fabricated through inkjet technology. Electrochemical behaviors the printed with different layers laser sintering intensities studied by cyclic voltammetry. Electrode sintered at 0.6 A double showed good reproducibility well linear relation in...
Under the immune pressure of cytotoxic T cells (CTLs), hepatitis B virus (HBV) evolves to accumulate mutations more likely within epitopes evade detection. However, little is known about specific patterns pressure-associated HBV mutation T-cell and their link disease progression. Here, we observed a correlation accumulated variants on core protein (HBc) with severity infection. Further analysis indicated that these substitutions were mostly located CD8+ HBc protein, which systematically...
// Junwei Hou 1 , Mengmeng Deng Xin Li Weiwei Liu Xiaoyu Chu Jing Wang 2 Feng Chen Songdong Meng CAS Key Laboratory of Pathogenic Microbiology and Immunology, Institute Microbiology, Chinese Academy Sciences (CAS), Beijing 100101, P.R. China Shenogen Pharma Group, Changping District, 102206, Correspondence to: Meng, e-mail: mengsd@im.ac.cn Chen, feng.chen@shenogen.com Keywords: ER-α36, gp96, ubiquitin, MAPK, breast cancer Received: April 26, 2015 Accepted: August 28, Published: September 10,...
Hepatocellular carcinoma (HCC) is a highly aggressive malignancy with increasing global prevalence and one of the leading causes cancer-related mortality in human population. Developing robust clinical prediction models prognostic stratification strategies crucial for developing individualized treatment plans. A range novel forms programmed cell death (PCD) plays role pathological progression advancement HCC, in-depth study PCD expected to further improve prognosis HCC patients. Sixteen...
Controllable microwire patterns are prepared by dominating the rupture of liquid films. Regular rhombic-shaped micropillar arrays serve as wetting defects to pin or depin liquids, yielding continuous, herringbone, bead-shaped polystyrene bead arrays. The results provide a deeper understanding controllable films and offer general strategy for organization polymers into structures needed wiring, interconnects, functional devices future microfabrication.
Abstract Diffuse large B-cell lymphoma (DLBCL) is the most common in adults. This study aimed to determine prognostic significance of endoplasmic reticulum (ER) stress-related genes DLBCL. ER were obtained from molecular signatures database. Gene expression data and clinical outcomes gene omnibus TCGA datasets collected, differentially expressed (DEGs) screened out. ontology enrichment analysis, kyoto encyclopaedia genomes pathway geneset analysis used analyse possible biological function...
In search of a practical alternative catalyst to costly and rare noble metals for hydrogen evolution reaction (HER), here we propose lamellar electrode architecture out engineered 2D MoS2 platelets that are stable in harsh electrochemical conditions, densified the catalytically active sites, enhanced interlamellar charge transfer. Energetic ion bombardment such as Ar beam milling (IBM) large-scale surface engineering technique can successfully create numerous edge states onto lamella with an...
Copper–silver (Cu–Ag) core–shell nanoparticles are promising for replacing the silver particles and flakes used in printed conductors current solar cells since they deliver good conductivity, chemical stability, optical performance, while also reducing content, thus significantly impacting cost. The bare offer excellent air stability thanks to silver-covered copper structure. We demonstrate a screen-printable paste use cell conductor applications. report morphology light reflection...
A hybrid nanoimprint soft lithography (HNSL) technique was used to fabricate nanopatterned sapphire substrates (NPSSs) for light-emitting diodes (LEDs). HNSL combines the high resolution of (NIL) and conformal contact lithography. The key component is mold, which consists rigid nanopatterns with an anti-adhesion coating on elastic poly(dimethylsiloxane) support. mold a 2-in. substrate through UV-NIL system double-layer resist, top UV-curable layer, underlying PMMA layer. Nickel dot arrays...
The effect on a crankshaft was not generally considered in the current optimum design of bearing for an internal combustion engine, but corresponding relation between dimensions and those journal exists. In this article, crankshaft-bearing system four-stroke, four-cylinder engine taken as research object, bearings considering strength carried out. necessity studied. Crankshaft one constraints establishing model bearings. particle swarm algorithm used to optimize results show that, compared...