A5005707459- Cardiac Arrhythmias and Treatments
- Cardiac electrophysiology and arrhythmias
- Atrial Fibrillation Management and Outcomes
- Cardiac pacing and defibrillation studies
- Heart Rate Variability and Autonomic Control
- Cardiovascular Syncope and Autonomic Disorders
- Cardiovascular Function and Risk Factors
- Cardiac Imaging and Diagnostics
- Ion channel regulation and function
- Pregnancy and preeclampsia studies
- Obstructive Sleep Apnea Research
- Cardiomyopathy and Myosin Studies
- Venous Thromboembolism Diagnosis and Management
- Acute Myocardial Infarction Research
- Metabolomics and Mass Spectrometry Studies
- Ectopic Pregnancy Diagnosis and Management
- Botulinum Toxin and Related Neurological Disorders
- Radiopharmaceutical Chemistry and Applications
- Wastewater Treatment and Nitrogen Removal
- Reproductive System and Pregnancy
- Gestational Trophoblastic Disease Studies
- Cancer Genomics and Diagnostics
- Trigeminal Neuralgia and Treatments
- Maternal and fetal healthcare
- Esophageal and GI Pathology
Yamagata University
1995-2025
Kansai Rosai Hospital
2022-2024
Showa University
2010-2020
Shibuya University Network
2020
Ministry of Health Labour and Welfare
2020
Showa University Hospital
2006-2018
Leipzig Heart Institute
2012
Kyoto University
2012
Leipzig University
2011
University of Aizu
2010
We sought to determine the relationship between size of left atrial isolated surface area (ISA) after pulmonary vein antrum isolation for paroxysmal fibrillation (AF) and rhythm outcome during a 12-month follow-up.One hundred one consecutive patients with AF (mean age, 59±11 years; median [range] history, 36 [24-96] months; mean size, 42±6 mm) were enrolled. The ISA was defined as ratio total antral excluding veins sum posterior wall area, while considering individual characteristics...
Background:This prospective randomized multicenter open-label trial evaluated whether sodium-glucose cotransporter-2 inhibitor (SGLT2-i) improves left ventricular (LV) pump function and suppresses elevation of LV filling pressure (LVFP) right systolic (RVSP) during exercise in type 2 diabetes mellitus (T2DM) patients.
<h3>Abstract</h3> Background/Aim: The widespread implementation of cancer genomic profiling (CGP) has led to an increase in the detection germline TP53 pathogenic variants (gTP53v) patients who do not meet classical Li-Fraumeni syndrome (LFS) criteria. present study aimed characterize clinical features and treatment outcomes gTP53v cases identified through routine CGP testing. Patients Methods: We conducted a retrospective analysis 43 with testing between June 2019 August 2024. Clinical...
The Multicenter Automatic Defibrillator Implantation Trial (MADIT) II investigators concluded that prophylactic use of an implantable cardioverter defibrillator (ICD) improved survival in patients with prior myocardial infarction (MI) and reduced the left ventricular ejection fraction (LVEF). However, it is unclear whether MADIT criteria for ICD implantation are appropriate Japanese patients.During period 1997 to 2001 90 (M/F: 75/15; mean age: 65+/-9 years) 3,258 who underwent elective...
Background: The recent studies showed that right ventricular (RV) pacing was associated with worsening of heart failure. aim this study is to clarify the clinical significance paced QRS duration during RV predict congestive failure (CHF) patients. Methods and Results: This enrolled in 92 patients atrioventricular block who underwent initial pacemaker implantation. automatically obtained by electrocardiography immediately after implantation then routine attendance at a clinic every 3 months....
Microvolt T-wave alternans (TWA) is reported to be closely associated with sudden cardiac death (SCD) and ventricular tachycardia (VT). Animal experiments revealed that microvolt TWA highly dependent on heart rate. The purpose of this study was determine whether patients at relatively low rates have increased vulnerability tachyarrhythmias.Subjects were 248 consecutive (158 men, 90 women; mean age, 59+/-17 years) who underwent electrophysiological from 1997 2000. recording made in sinus...
This study has evaluated whether candesartans prevent the recurrence of atrial fibrillation (AF) and decrease type III procollagen-N-peptide (PIIINP) levels. A total 153 patients with AF were enrolled in this study. Three groups compared; candesartan group was treated plus bepridil (n = 52); carvedilol 51); alone 50). The primary end point length time to all ultimately followed-up for 730 days. Serum levels biomarkers measured at baseline after 24 months. Maintenance sinus rhythm achieved 25...
Background:Although clinical trials demonstrate that the elderly with atrial fibrillation have risks of thrombosis and bleeding, relationship between aging coagulation fibrinolytic system in "real-world" cardiology outpatients is uncertain.
Abstract For leukotriene receptor antagonists (LTRAs), especially pranlukast, safety data during pregnancy is limited. Therefore, we conducted a prospective, two‐centered cohort study using from teratogen information services in Japan to clarify the effects of LTRA exposure on maternal and fetal outcomes. Pregnant women who being counseled drug use at two facilities were enrolled. The primary outcome this was major congenital anomalies. incidence anomalies exposed montelukast or pranlukast...
Ovarian mature cystic teratomas (MCT) are usually benign. However, squamous cell carcinoma (SCC) develops in 0.17-2% of MCT. Because its low frequency, the optimal treatment for this disease is unclear. We present a case SCC arising from Our patient was 30-year-old nulliparous woman complaining right lower abdominal pain, who referred to our hospital pelvic solid mass with suspected malignant ovarian tumor. A diagnosis MCT based on elevation antigen and imaging. After surgery remove tumor,...
The present study examined the effects of foods containing lipopolysaccharides from Pantoea agglomerans (LPSp) on eye–nose allergic symptoms using a double-blind, placebo-controlled, randomized, parallel-group comparative research design. Sixty-three Japanese individuals aged 20–65 years with were included in this and assigned to LPS (480 μg/day)-containing food placebo groups. Data subjective antiallergic medication during 8-week period evaluated. immunoglobulin E (IgE) eosinophil counts...
This randomised, placebo-controlled, double-blind, parallel-group study aimed to determine whether encapsulated Ashitaba chalcone (16 mg comprising 10.1 4-hydroxyderricin and 5.9 xanthoangelol) could reduce obesity in 17 men 25 women with a body mass index (BMI) of < 30. Participants ingested capsules containing either the or placebo daily for 12 weeks. The primary endpoint was changes visceral fat areas determined by computed tomography (CT) at baseline, 8 weeks later. endpoint, abdominal...
Acute coronary syndrome (ACS) is a life-threatening condition that requires prompt diagnosis and therapeutic intervention. Although serum troponin T creatinine kinase-MB (CK-MB) are established biomarkers for ACS, it may take several hours to reach diagnostic values ACS. In this study, we attempted explore novel ACS with higher sensitivity than of CK-MB. The metabolomic profiles 18 patients upon hospital arrival those the age-matched control (HC) group consisted 24 healthy volunteers were...
Recurrent ventricular tachycardia (VT) and fibrillation (VF), the so-called "electrical storm" (ES) occurs at various stages of acute myocardial infarction (AMI), but its incidence, background, short-term prognosis remain unclear.
Transthoracic epicardial ablation can be an alternative to conventional treatment for critical pathways of ventricular tachycardia located in the epicardium. However, usefulness and safety close coronary arteries (CA) is not clear. The purpose present experimental animal study was analyze efficacy radiofrequency (RF) CA.Of left ventricle-epicardium ablated sites, 35 lesions (20 with cooling 15 without cooling) were CA (left anterior descending artery < or = mm) 33 (23 10 further from CA. For...