A5101573744- Pain Mechanisms and Treatments
- Healthcare Policy and Management
- Primary Care and Health Outcomes
- Musculoskeletal pain and rehabilitation
- Ion channel regulation and function
- Laser Applications in Dentistry and Medicine
- Health Systems, Economic Evaluations, Quality of Life
- Geriatric Care and Nursing Homes
- Botulinum Toxin and Related Neurological Disorders
- Bladder and Urothelial Cancer Treatments
- Spine and Intervertebral Disc Pathology
- Neuropeptides and Animal Physiology
- Spinal Cord Injury Research
- Anesthesia and Pain Management
- Genomics and Rare Diseases
- Mycotoxins in Agriculture and Food
- Folate and B Vitamins Research
- Global Health Care Issues
- Tuberculosis Research and Epidemiology
- Helicobacter pylori-related gastroenterology studies
- Urinary and Genital Oncology Studies
- Mental Health Treatment and Access
- Pain Management and Treatment
- Prostate Cancer Diagnosis and Treatment
- Liver Disease Diagnosis and Treatment
Air Force Medical University
2025
Xijing Hospital
2025
Shenzhen Children's Hospital
2024
Kunming Children's Hospital
2023-2024
Kunming Medical University
2023-2024
Ningbo University
2024
Children's Mercy Hospital
2024
Peking University First Hospital
2017-2023
Peking University
2017-2023
Chinese Academy of Medical Sciences & Peking Union Medical College
2006-2023
Our goal was to evaluate the feasibility, safety and effectiveness of KangDuo Surgical Robot-01 (KD-SR-01) system for robot-assisted radical prostatectomy (RARP).
Nitric oxide synthase (NOS), an enzyme involved in synthesis of nitric (NO), has been localized many diverse cell types. In the CNS and PNS, discrete neuron groups express NOS constitutively. Recent evidence indicates that is inducible neurons normally not expressing NOS. After transection peripheral nerves, expression was significantly up-regulated axotomized sensory ganglion cells, whereas corresponding motor induced unless axon regeneration prevented ensuing death became massive. Studies...
Sensory abnormalities and changes in spontaneous behavior were examined after a photochemically induced ischemic lesion of the rat sciatic nerve. Male adult rats anesthetized nerve was exposed. After intravenous injection photosensitizing dye, erythrosin B, exposed irradiated just proximal to trifurcation with light from an argon laser. Three different irradiation times used, 30 s, 1 2 min. In sham-operated rats, for min without prior B. Rats tested presence mechanical, cold heat allodynia...
Intraoperative blood salvage (IBS) reduces homologous transfusion in orthotopic liver transplantation (OLT), but may carry with it the risk of reinfusing tumor cells patients hepatocellular carcinoma (HCC). The use leukocyte depletion filters (LDFs) for removal is rarely reported clinical OLT. aims this study were to evaluate frequency cell contamination surgical field during OLT HCC recipients and investigate efficiency additional LDFs eliminating from IBS.Thirty-two preoperatively elevated...
Objective: This study identifies independent predictive indicators to distinguish autoimmune gastritis from Helicobacter pylori (H. pylori)-induced atrophic and validates their diagnostic performance compare laboratory of H. pylori-induced gastritis. Methods: A retrospective comparison examination was conducted for chronic patients with involvement the gastric fundus corpus, who were followed up at Department Gastroenterology, Xijing Hospital, January 2014 September 2024. Receiver operating...
Adrenal chromaffin cells produce analgesic substances, such as catecholamines and enkephalins, intrathecal (i.t.) implantation of either allografted adrenal tissue or xenogenic antinociception in animals. We evaluated the effect bovine a model central pain which rats exhibit chronic allodynia-like behavior after photochemically induced ischemic spinal cord injury. Bovine endothelial were injected i.t. onto lumbar their effects on mechanical cold behaviors studied for up to 8 weeks. The was...
Health care systems frequently have to decide whether implement interventions designed reduce gaps in the quality of care. A lack information on cost these is often cited as a barrier implementation. In this article, we describe methods for estimating implementing complex intervention. We review related direct measurement labor, supplies and space, technology, research costs. also discuss several issues that affect estimates implementation studies, including factor prices, fidelity,...
The development of neuropathic-like behaviors following unilateral ischemic injury to the sciatic nerve was examined and compared in four rat strains: Sprague–Dawley (SD), Wistar–-Kyoto (WK), spontaneously hypertensive (SHR) Dark–Agouti (DA). We have also two sub-strains SD rats supplied from different vendors (SD-BK SD-DK). responses mechanical, heat or cold stimuli both hind paws were measured before regularly after for up 10 weeks. Spontaneous paw lifting changes posture examined....
Abstract Systemic sepsis is a known risk factor for bronchopulmonary dysplasia (BPD) in premature infants, disease characterized by dysregulated angiogenesis and impaired vascular alveolar development. We have previoulsy reported that systemic endotoxin dysregulates pulmonary resulting simplification mimicking BPD neonatal mice, but the underlying mechanisms remain unclear. undertook an unbiased discovery approach to identify novel signaling pathways programming sepsis-induced deviant lung...
Abstract The mechanisms governing brain vascularization during development remain poorly understood. A key regulator of developmental is delta like 4 (DLL4), a Notch ligand prominently expressed in endothelial cells (EC). Exposure to hyperoxia premature infants can disrupt the and functions cerebral blood vessels lead long‐term cognitive impairment. However, its role vascular impact postnatal on DLL4 expression mouse EC have not been explored. We determined pattern downstream signalling gene...
In an effort to assess and reduce gender-related quality gaps, the Veterans Health Administration (VHA) has promoted gender-based research. Historically, such appraisals have often relied on secondary databases, with little attention methodological implications of fact that VHA provides care some nonveteran patients.To determine whether conclusions about gender differences in utilization cost change after accounting for veteran status.Cross-sectional.All users 2002 (N = 4,429,414).Veteran...
Leucine rich-repeat kinase 2 (LRRK2) has been considered a susceptibility gene for ulcerative colitis (UC), and its protein abundance was enhanced in the peripheral blood mononuclear cells (PBMCs) from UC cohorts as compared to healthy volunteers. In preclinical models of colitis, Lrrk2 deficiency ameliorated dextran sodium sulfate (DSS)-induced progression, whereas processes were aggravated by R1441C mutation. While intestinal macrophages (MФs) knock-out (Lrrk2−/−) mice exhibited tendency...
The photoyellowing progress of silk fibroin and its influence factors under ultraviolet irradiation have been studied, which was conducted by combining different wavelengths, irradiancies, times. blue-ray whiteness after tested to characterize the course fibroin. result shows that degree varies significantly wavelengths with increasing in irradiancy at 313-nm wavelength, aggravates correspondingly, while 340-nm wavelength has little obvious impact. Additionally, is positively correlated...
The present study has assessed the efficacy and potency of systemic, intrathecal (i.t.) intracerebroventricular (i.c.v.) morphine in alleviating a chronic mechanical allodynia‐like behaviour rat model central pain after spinal cord injury. anti‐allodynic was compared to its antinociceptive both spinally injured normal rats. Systemic (intraperitoneal or subcutaneous) did not significantly relieve allodynia up 3 mg/kg cumulative dose, which sedative. Mechanical only relieved by 10 caused...
BACKGROUND Post-hepatectomy liver failure (PHLF) is a serious complication and leading cause of death after hepatectomy, an accurate prediction PHLF important for improvement prognosis hepatectomy. AIM To retrospectively analyze the risk factors postoperative in patients undergoing hepatectomy tumors. METHODS The clinical data 80 our hospital from June 2018 to January 2020 were collected. With laboratory examination as well pre- post-operative abdominal three-dimensional reconstructive...
We examined the effects of intrathecal (i.t.) selective opioid receptor agonists in alleviating mechanical and cold allodynia spinally injured rats. Both DAMGO ([D-Ala2,N-Me-Phe4,Gly5-ol]-enkephalin, a μ-opioid agonist) DPDPE ([D-Phe2,D-Phe5]-enkephalin, δ-opioid dose-dependently relieved chronic allodynia-like behavior at doses for their respective receptors. The anti-allodynic effect was reversed by μ- antagonists CTOP (D-Phe-Cys-Tyr-D-Trp-Orn-Thr-Pen-Thr-NH2) naltrindole, respectively. In...