A5075231996- Aluminum Alloys Composites Properties
- Immune cells in cancer
- Antibiotic Resistance in Bacteria
- DNA and Biological Computing
- Aluminum Alloy Microstructure Properties
- Microstructure and mechanical properties
- Advanced ceramic materials synthesis
- Chemokine receptors and signaling
- Sodium Intake and Health
- Remote Sensing in Agriculture
- Advanced biosensing and bioanalysis techniques
- Gut microbiota and health
- Nanoplatforms for cancer theranostics
- Cancer-related molecular mechanisms research
- Advanced Welding Techniques Analysis
- Bacterial biofilms and quorum sensing
- Cooperative Communication and Network Coding
- Genomics and Phylogenetic Studies
- Industrial Vision Systems and Defect Detection
- Angiogenesis and VEGF in Cancer
- Aquaculture Nutrition and Growth
- Full-Duplex Wireless Communications
- Cancer Research and Treatments
- Advanced Wireless Communication Technologies
- Invertebrate Immune Response Mechanisms
Chinese Academy of Sciences
2015-2025
Beijing Institute of Genomics
2018-2025
Shanghai Center For Bioinformation Technology
2020-2025
Institute of Chemistry named after V.I. Nikitin
2024
Sichuan University
2023
University of Science and Technology of China
2019-2020
Nanjing Medical University
2018-2020
Beijing University of Posts and Telecommunications
2018-2019
Institute of Cardiology
2016
Tianjin University of Science and Technology
2015
Nanoparticle reinforced aluminum matrix composites fabricated by a high energy ball milling method showed significantly improved strength, however, their ductility was relative lower. This study proposed for the first time heterogeneous structure strategy toward good strength and synergy Al composites. Nanoscale Al2O3 particulate pure were as model materials. Three procedures conducted to construct uniform ultrafine grain, random bi-modal lamella grain structures. It shown that all exhibited...
IntroductionIncreasing evidence shows that gut microbiota dysbiosis may play important roles in the occurrence and progression of Parkinson's disease (PD), but findings are inconsistent. Besides, effect family environment on remains unclear.MethodsWe characterized microbial compositions 63 PD patients, healthy spouses (HS) 74 people (HP) using 16S rRNA sequencing. Clinical phenotypes composition were analyzed comprehensively.ResultsThere markedly different among PD, HS HP samples by...
Hypervirulent carbapenem-resistant Klebsiella pneumoniae (hv-CRKP) poses an increasing public health risk due to its high treatment difficulty and associated mortality, especially in bone marrow transplant (BMT) patients. The emergence of strains with multiple resistance mechanisms further complicates the management these infections. We isolated characterized a novel ST11-KL64 hv-CRKP strain from pediatric transplantation patient. Antimicrobial susceptibility testing was performed determine...
Myeloid-derived suppressor cells (MDSC) have recently emerged as one of the central regulators immune system. In recent years, interest in understanding MDSC biology and applying for therapeutic purpose has exploded exponentially. Despite progress biology, mechanisms underlying development from expansion activation to polarization different diseases remain poorly understood. More studies demonstrated that two subsets, M (monocytic)-MDSC G (granulocytic)-MDSC, are able polarize a classically...
Here, we report a multidrug-resistant hypervirulent Klebsiella pneumoniae (MDR-HvKP) strain of sequence type 23 (ST23) with rare hybrid plasmid harboring virulence genes and bla CTX-M-24 , analyze the genetic basis for relationship between genotypes MDR-hypervirulence phenotypes. Further analysis indicates that is formed by IS 903D -mediated intermolecular transposition gene into plasmid.
The rapid spread of carbapenemase-producing Klebsiella pneumoniae (cpKP) poses serious threats to public health; however, the underlying genetic basis for its dissemination is still unknown. We conducted a comprehensive genomic epidemiology analysis on 420 cpKP isolates collected from 70 hospitals in 24 provinces/autonomous regions/municipalities China during 2009-2017 by short-/long-read sequencing. results showed that most were categorized into clonal group 258 (CG258), which ST11 was...
Tuberculosis (TB) has surpassed HIV as the leading infectious disease killer worldwide since 2014. The main pathogen, Mycobacterium tuberculosis (Mtb), contains ~4,000 genes that account for ~90% of genome. However, it is still unclear which these are primary/secondary, responsible generality/individuality, and interconvert during evolution. Here we utilized a pan-genomic analysis 36 Mtb genomes to address questions. We identified 3,679 core (i.e., primary) genes, determining their...
ABSTRACT Type 2 diabetes mellitus (T2DM) is a rapidly increasing metabolic disorder that poses significant threat to global public health. Recent evidence suggests targeting the gut microbiota through dietary and pharmaceutical interventions can effectively manage T2DM. In this study, we developed novel Chinese herbal formula, CCM, specifically for T2DM, composed of Coptis rhizoma , Cinnamomi cortex Mume fructus . To evaluate CCM’s efficacy explore its underlying mechanisms, particularly...
Litopenaeus vannamei (Boone, 1931) postlarvae with average initial body weight of 0.089 g were reared in 75-litre PVC tanks for 40 days at salinities 30 and 60 l −1 . The shrimps fed compound feed containing protein levels 35, 40, 45 50%, respectively. Salinity had a remarkable effect on growth survival L. juveniles. Higher rate lower observed salinity. Dietary level affected the juveniles both salinities, increased dietary range 35 to 45%, but decreased slightly 50% protein. Broken line...
Poly-β-hydroxybutyrate (PHB) is microbial carbon and energy storage polymer, which can be degraded into water-soluble β-hydroxybutyric acid in the gastrointestinal tract of aquatic animals. A 60-day culture experiment was performed using Chinese mitten crab, Eriocheir sinensis (Milne-Edwards) juveniles with an average initial body weight 0.74 ± 0.06 g were fed a diet supplemented 0%, 0.5%, 1%, 3% or 5% PHB. PHB dietary supplementation 1% significantly improved gain, moulting frequency...
1.2 mm thick DP1180 advanced ultra-high-strength steel were successfully friction stir spot welded (FSSWed) with additional water cooling. No hook defect and obvious keyhole observed in the joints when using a specially designed WC-Co tool. Softening of heat-affected zone was substantially suppressed lap shear strength obviously enhanced via The water-cooled attributed to grain refinement, formation untempered martensite effective restraint tool softening underwater. Accordingly, maximum...
Abstract DNA storage is a new digital data technology based on specific encoding and decoding methods between 0 1 binary codes of A-T-C-G quaternary DNAs, which expected to develop into major form in the future due its advantages (such as high density, long time, low energy consumption, convenience for carrying, concealed transportation multiple encryptions). In this review, we mainly summarize recent research advances four main technology: direct mapping method early-stage, fountain code...
Laboratory level autoclave pyrolysis experiments of ChineseLiushuhe oil shale have been conducted at different heating temperatures and pressures to simulate underground in-situ thermal conversion.Effects water metallic ions on investigated.In the presence water, generates bitumen as an intermediate product first, then produces gas takes place.With increasing temperature, yields increase gradually, while yield initially increases (max.at 300 °C) decreases.Compared with modified Fisher Assay,...
Two Artemia culture experiments were conducted in a zero water exchange system at salinity 80 g L−1. In Experiment I, different carbon sources including molasses, glucose, sucrose and corn flour given to supplement suboptimal feeding with the microalgae Dunaliella viridis, whereas control was fed only D. viridis. II, molasses supplemented medium, as well bacteria Alkalibacterium sp. or archaea Halobacterium sp., isolated from brine local saltponds. The groups viridis molasses. Our study...