- Teaching and Learning Programming
- Dementia and Cognitive Impairment Research
- Educational Games and Gamification
- Mental Health and Patient Involvement
- Online Learning and Analytics
- Information Systems Education and Curriculum Development
- Health Systems, Economic Evaluations, Quality of Life
- Religion, Spirituality, and Psychology
- Gender and Technology in Education
- Obesity, Physical Activity, Diet
- Bipolar Disorder and Treatment
- Online and Blended Learning
- Higher Education Learning Practices
- Delphi Technique in Research
- Diet and metabolism studies
- Experimental Learning in Engineering
- Innovative Teaching and Learning Methods
- Academic integrity and plagiarism
- Grief, Bereavement, and Mental Health
- Open Education and E-Learning
- Suicide and Self-Harm Studies
- Psychiatric care and mental health services
- Healthcare innovation and challenges
- Cardiovascular Disease and Adiposity
- Geriatric Care and Nursing Homes
Medical University of South Carolina
2014-2024
University College London
2007-2023
Faculty (United Kingdom)
2020-2023
Pine Rest Christian Mental Health Services
2017-2022
University of Kent
2003-2017
University of Canterbury
2008-2016
Occupational Safety & Health Administration
2013-2016
North East London NHS Foundation Trust
2012-2015
Carter Center
2015
The University of Western Australia
2014
Abstract The rapid proliferation of many different engineered nanomaterials (defined as materials designed and produced to have structural features with at least one dimension 100 nanometers or less) presents a dilemma regulators regarding hazard identification. International Life Sciences Institute Research Foundation/Risk Science convened an expert working group develop screening strategy for the identification nanomaterials. report elements rather than detailed testing protocol. Based on...
BackgroundStudies in monkeys with intranasally instilled gold ultrafine particles (UFPs; < 100 nm) and rats inhaled carbon UFPs suggested that solid deposited the nose travel along olfactory nerve to bulb.MethodsTo determine if translocation occurs for other metal assess potential health effects, we exposed groups of manganese (Mn) oxide (30 nm; ~ 500 μg/m3) either both nostrils patent or right nostril occluded. We analyzed Mn lung, liver, bulb, brain regions, performed gene protein...
Macrophage inflammatory proteins 1α and 2 (MIP-1α, MIP-2) are members of a growing family cytokines thought to play role in host defense. MIP-1α MIP-2 were previously identified the mouse shown stimulate cell recruitment. To better understand potential lung defense, we investigated ability rat cells express mRNA for and/or secrete vitro characterized expression these after vivo exposure silica (SiO2) or titanium dioxide (TiO2). In response lipopolysaccharide, alveolar macrophages expressed...
Abstract Aim The ICD‐11 Personality Disorders Committee has proposed five personality domains: Detached, Anankastic, Negative Affective, Dissocial and Disinhibited. We attempted to validate these domains in a large sample of patients with major depression. Methods Participants from treatment studies received SCID assessment interview assess DSM‐5 disorder symptoms. symptoms were assigned the domains. Confirmatory factor analysis an exploratory framework was used test hypothesized domain...
There has been a conceptual shift in toxicological studies from describing what happens to explaining how the adverse outcome occurs, thereby enabling deeper and improved understanding of biomolecular mechanistic profiling can inform hazard identification improve risk assessment. Compared traditional toxicology methods, which have heavy reliance on animals, new approaches generate data are becoming available for safety assessment chemicals, including high-throughput high-content screening...
article Addressing student cheating: definitions and solutions Share on Authors: Martin Dick Monash University, Australia AustraliaView Profile , Judy Sheard Cathy Bareiss Olivet Nazarene University UniversityView Janet Carter of Kent at Canterbury, UK UKView Donald Joyce UNITEC Institute Technology, New Zealand ZealandView Trevor Harding Kettering Cary Laxer Rose-Hulman Technology TechnologyView Authors Info & Claims ACM SIGCSE BulletinVolume 35Issue 2June 2003 pp...
<h3>Introduction</h3> There is increasing evidence that imaging with [<sup>123</sup>I]FP-CIT SPECT helpful in differentiating dementia Lewy bodies (DLB) from Alzheimer9s disease (AD) but it not known how well the scan performs DLB frontotemporal (FTD). <h3>Method</h3> We compared striatal dopamine transporter (DAT) binding FTD (n=12), (n=10) and AD (n=9) by visually rating caudate putamen on scans. <h3>Results</h3> The majority (9/10) of cases had an abnormal a significant reduction uptake...
Receiving a timely and accurate diagnosis gaining access to age-appropriate support for younger people living with dementia (YPD) remains challenge both in the UK internationally because focus of most services is primarily upon needs older people. The political case improve YPD depends establishment an understanding clinical symptoms, unequivocal evidence base about need evaluation size population affected. This short report assesses from international studies regarding service design...
Increased class sizes are forcing academics to reconsider approaches setting and marking assessments for their students. Distributed distance learning creating some of the biggest changes. Some educators embracing new technologies but others more wary what they do not know. In order address this issue it is first necessary investigate types assessment currently in use perceptions that held by with without experience becoming available.In paper we present findings an international survey...
A major use of multi-walled carbon nanotubes (MWCNTs) is as functional fillers embedded in a solid matrix, such plastics or coatings. Weathering and abrasion the matrix during can lead to environmental releases MWCNTs. Here we focus on protocol identify quantify primary release induced by weathering, assess reproducibility, transferability, sensitivity towards different materials uses. We prepared 132 specimens two polymer-MWCNT composites containing same grade MWCNTs used earlier OECD...
Young onset dementia is associated with distinctive support needs but existing research on service provision has been largely small scale and qualitative. Our objective was to explore use, cost satisfaction across the UK.Information about socio-demographic characteristics, use were gathered from people young (YOD) and/or a family member/supporter via national survey.Two hundred thirty-three responses analysed. Diagnosis most commonly received through Memory Clinic or Neurology. The type of...
Objectives Studies on service needs of people with young onset dementia have taken a problem-oriented approach resulting recommendations focusing reducing shortcomings. This study aimed to build 'what works' in real-life practice by exploring the nature post-diagnostic support services that were perceived positively younger and carers.Method Positive examples gathered between August 2017 September 2018, via national survey. Inductive thematic analysis was employed explore experienced...
Synaptic pathology is proposed to be integral the clinical expression of Alzheimer disease (AD). Most studies have assessed only vesicle protein synaptophysin as a measure synaptic integrity. The interrelationships synaptophysin, other presynaptic proteins, cholinergic system, and severity dementia in AD remain unclear. We studied proteins syntaxin SNAP-25, along with choline acetyltransferase (ChAT) activity prefrontal cortex (BA 46) samples from 18 subjects 16 controls. Mean values...
Significant attention has been paid in recent years to student attrition, and rightly so, since rates are rising need diagnosing. Little seems have the converse--the successful student. It is widely believed among academics that high school grades--in UK, A-levels--are poor indicators of final performance, although we persist using them as entry criteria absence any other index into a student's potential. This study, conducted parallel two traditional (pre-1992) UK universities, focuses on...
Background Routine psychiatric assessments tailored to older patients are often insufficient identify the complexity of presentation in younger with dementia. Significant overlap between disorders and neurodegenerative disease means that high rates prior incorrect diagnosis common. Long delays diagnosis, misdiagnosis lack knowledge from professionals key concerns. No specific practice guidelines exist for young-onset dementia (YOD). Aims The review evaluates current evidence about best guide...
Suicidal behavior is a leading cause of injury and death, so research identifying protective factors essential. Research suggests gratitude life hardships patience are character strengths that might protect against the deleterious association struggles with ultimate meaning suicide risk. However, no studies have evaluated their utility among people experiencing acute/severe mental health concerns.We tested function cross-sectional data from adults (Mage = 31.83 years; SD 14.84; range 18-82)...
Background We tested the validity of two screens for depression in older African–Caribbean adults, 15-item Geriatric Depression Scale (GDS) and a new Caribbean Culture-Specific Screen emotional distress (CCSS). Two independent criteria were used validity: (a) psychiatric diagnosis derived from GMS–AGECAT, (b) culturally sensitive assessment mental disorder, tool developed with local religious healers. Method One hundred sixty-four consecutive primary care users, aged 60 years or older,...
Abstract The solid reaction products from pyrolysis of polyethylene terephthalate in the presence and absence red phosphorus were characterized by CP/MAS 13 C‐NMR, FR‐IR, MAS 31 P‐NMR spectroscopy. Over temperature range 300–400°C, was converted a sealed vial to highly crosslinked polymer terephthalic acid. Pyrolysis phosphorus, which functions as flame retardant increasing amount char, yielded an intractible polyaromatic phosphate ester. After thermal cleavage with formation free carboxyl...
Few studies in positive psychology have examined associations between virtues and mental health highly distressed samples. This study demonstrates the relevance of virtue patience, conceptualized as capacity to calmly face frustration suffering, within a spiritually integrated treatment program offering inpatient psychiatric hospitalization. Previously evaluated non-distressed samples, patience may increase during hospitalization facilitate outcomes. The present found was inversely related...
There is a significant lack of evidence regarding optimum models for service provision in young onset dementia (YOD). Our study aim was to gather detailed information about services experienced as helpful by those with YOD and family carers. The objective identify the core features these inform design, delivery improvements. A qualitative approach based on appreciative inquiry used, posing open-ended questions helpful, part national UK survey people We used inductive thematic analysis...
Abstract Evidence on post-diagnostic support for people with young onset dementia is scarce. Previous studies have employed a problem-focused approach; however, evidence ‘what works’ in real-life practice essential to develop recommendations service design and delivery. This study aimed provide insight into from the perspectives of their supporters. We gathered free-text responses positive experiences via UK cross-sectional survey. Inductive thematic analysis was used identify objectives...