A5100714226- Tea Polyphenols and Effects
- Fermentation and Sensory Analysis
- Food Quality and Safety Studies
- Advanced biosensing and bioanalysis techniques
- Electrochemical sensors and biosensors
- Carbon and Quantum Dots Applications
- Hepatitis B Virus Studies
- Phytochemicals and Antioxidant Activities
- Biosensors and Analytical Detection
- CRISPR and Genetic Engineering
- interferon and immune responses
- Hepatitis C virus research
- Traditional Chinese Medicine Analysis
- Liver Disease Diagnosis and Treatment
- Autophagy in Disease and Therapy
- Molecular Sensors and Ion Detection
- Mosquito-borne diseases and control
- Circular RNAs in diseases
- Viral Infections and Vectors
- HIV Research and Treatment
- Complementary and Alternative Medicine Studies
- Gastrointestinal motility and disorders
- Inflammatory Biomarkers in Disease Prognosis
- Sulfur Compounds in Biology
- Cardiovascular, Neuropeptides, and Oxidative Stress Research
Hunan Agricultural University
2023-2025
China XD Group (China)
2023-2024
Yale University
2024
Chinese Academy of Medical Sciences & Peking Union Medical College
2023-2024
Shenzhen Blood Center
2024
Hanzhong Central Hospital
2024
Hunan University
2024
Wenzhou Medical University
2023
Affiliated Eye Hospital of Wenzhou Medical College
2023
Xidian University
2023
A fluorescent method for detection of tetracyclines (TCs) in milk was developed by using the NH2-MIL-53(Al) nanosensor synthesized via a one-pot hydrothermal method. The had crystalline nanoplates structure with rich groups −NH2 and −COOH. −NH2/–COOH reacted −CO–/–OH TCs to form complex. electron from NH2-BDC ligand transferred TCs. interacted hydrogen bonding. quenching efficiency inner filter effect (IFE) calculated contribute 57–89%. synergistic photoinduced transfer (PET) IFE account...
Respiratory infections pose a serious threat to global public health, underscoring the urgent need for rapid, accurate, and large-scale diagnostic tools. In recent years, CRISPR/Cas (clustered regularly interspaced short palindromic repeats/CRISPR-associated) system, combined with isothermal amplification methods, has seen widespread application in nucleic acid testing (NAT). However, achieving single-tube reaction system containing all necessary components is challenging due competitive...
BACKGROUND As there is no effective treatment for irritable bowel syndrome (IBS), many patients turn to traditional Chinese medicine (TCM) possible cure. We investigated the therapeutic efficacy of an ancient herbal formula in with diarrhea-predominant IBS. METHODS This was a randomized double-blinded placebo-controlled trial. IBS predominant diarrhea symptoms that fulfilled Rome II criteria were recruited. The diagnosis verified by TCM herbalist using criteria. Eligible receive standard...
Based on the enhancing effects of norepinephrine (NE), epinephrine (EP), dopamine (DA) and 5-hydroxytryptamine (5-HT) chemiluminescence (CL) reaction between [Ag(HIO6 )2 ](5-) luminol in alkaline solution, a high-performance liquid chromatography (HPLC) method with CL detection was explored for sensitive determination monoamine neurotransmitters first time. The UV-visible absorption spectra were recorded to study enhancement mechanism reaction. HPLC separation NE, EP, DA 5-HT achieved...
Summary Background : Traditional Chinese Medicine was frequently used by patients with irritable bowel syndrome. Aim To evaluate the agreement on diagnoses and prescription of syndrome among practitioners. Methods Consecutive were interviewed independently four The study divided into three phases: (i) blinded individual assessment, (ii) discussion to achieve consensus diagnosis treatment, (iii) assessment based consensual diagnostic criteria. Patients other causes diarrhoea recruited as...
While extensive research has focused on the flavor of Fu brick tea (FBT), perceptual interactions among its aromatic components remain unclear. To address this, twenty representative aroma compounds were selected from FBT to determine their thresholds and evaluate by analyzing threshold changes before after mixing. The results revealed discrepancies between determined literature values, particularly for α-terpineol, methyl heptenone, geranylacetone, which demonstrated ratios 73.54, 6.62,...
Significant differences exist in aroma and taste of different grades large-leaf black tea. In this study, sensory histology combined with metabolomics were used to investigate the characteristics phytochemical profiles Huangpu tea (HPBT). Sensory evaluation showed that high grade HPBT had intensity pekoe, fresh umami, scores declining decreasing grades. 173 non-volatiles identified, which 23 marker metabolites could be as discrimination taste. addition, 154 volatile compounds identified...
Dry eye disease (DED) is a prevalent chronic characterized by an aberrant inflammatory response in ocular surface mucosa. The immunological alterations underlying DED remain largely unknown. In this study, we employed single-cell transcriptome sequencing of conjunctival tissue from environment-induced mice to investigate multicellular ecosystem and functional changes at different stages. Our results revealed epithelial subtype with fibroblastic characteristics pro-inflammatory effects...
Abstract Cytidine/uridine monophosphate kinase 2 (UMP‐CMP 2, CMPK2) has been reported as an antiviral interferon‐stimulated gene (ISG). We previously observed that the expression of CMPK2 was significantly upregulated after Zika Virus (ZIKV) infection in A549 cells. However, association and underlying mechanisms between induction ZIKV replication remain to be determined. investigated during effect on A549, U251, Vero, IFNAR‐deficient U5A its parental 2fTGH cells, Huh7 RIG‐I‐deficient...
Over the past decade, increasing evidence has shown that circular RNAs (circRNAs) play important regulatory roles in viral infection and host antiviral responses. However, reports on role of circRNAs Zika virus (ZIKV) are limited. In this study, we identified 45 differentially expressed ZIKV-infected A549 cells by RNA sequencing. We clarified a downregulated circRNA, hsa_circ_0007321, regulates ZIKV replication through targeting miR-492 downstream gene NFKBID. NFKBID is negative regulator...
Mitophagy is a selective degradation mechanism that maintains mitochondrial homeostasis by eliminating damaged mitochondria. Many viruses manipulate mitophagy to promote their infection, but its role in Zika virus (ZIKV) unclear. In this study, we investigated the effect of activation on ZIKV replication uncoupling agent niclosamide. Our results demonstrate niclosamide-induced inhibits fragmented mitochondria, both vitro and mouse model ZIKV-induced necrosis. Niclosamide induces...
The aim of the present paper was to study influence neck muscle activation on head and injuries vehicle occupants in frontal impacts. A mixed dummy-human finite element model developed simulate a impact. head-neck part Hybrid III dummy replaced by well-validated FE with passive active characteristics. validated 15 G volunteer tests conducted Naval Biodynamics Laboratory. effects dynamic responses three impact intensities, low speed (10 km/h), medium (30 high (50 were studied. results showed...
Root system architecture (RSA) and tiller are important agronomic traits. However, the mechanisms of IGT family genes regulate RSA development in different rice varieties remain unclear. In this study, we demonstrated that 38 obtained from Yuanyang Hani’s terraced fields with could be classified into six groups based on ratio root length width. We found a positive correlation between (including width, length, area) number most varieties. Furthermore, Deeper Rooting 1 ( DRO1 ), LAZY1 , TAC1...