A5083223878- Coronary Interventions and Diagnostics
- Acute Myocardial Infarction Research
- Atherosclerosis and Cardiovascular Diseases
- Tissue Engineering and Regenerative Medicine
- Mesenchymal stem cell research
- Tracheal and airway disorders
- Antiplatelet Therapy and Cardiovascular Diseases
Charité - Universitätsmedizin Berlin
2017-2020
Berlin Institute of Health at Charité - Universitätsmedizin Berlin
2020
Boston Children's Hospital
2014
Harvard University
2014
Witten/Herdecke University
2014
Abstract Aims Acute coronary syndromes with intact fibrous cap (IFC-ACS), i.e. caused by plaque erosion, account for approximately one-third of ACS. However, the underlying pathophysiological mechanisms as compared ACS rupture (RFC-ACS) remain largely undefined. The prospective translational OPTICO-ACS study programme investigates first time microenvironment ACS-causing culprit lesions (CL) molecular high-resolution intracoronary imaging and simultaneous local immunological phenotyping....
Obliterative bronchiolitis (OB) remains the most significant cause of death in long-term survival lung transplantation. Using an established murine heterotopic tracheal allograft model, effects different routes administration bone marrow-derived multipotent stromal cells (MSCs) on development OB were evaluated. Tracheas from BALB/c mice implanted into subcutaneous tissue major histocompatibility complex- (MHC-) disparate C57BL/6 mice. At time transplant, MSCs administered either systemically...