- Mechanical Circulatory Support Devices
- Cardiac Arrest and Resuscitation
- Cardiac Structural Anomalies and Repair
- RNA and protein synthesis mechanisms
- CRISPR and Genetic Engineering
- Heart Failure Treatment and Management
- Viral Infectious Diseases and Gene Expression in Insects
- Mitochondrial Function and Pathology
- Cardiac Arrhythmias and Treatments
- Metabolism and Genetic Disorders
- Sarcoidosis and Beryllium Toxicity Research
- RNA regulation and disease
- Bacterial Genetics and Biotechnology
- Congenital Heart Disease Studies
- Microtubule and mitosis dynamics
- Hemodynamic Monitoring and Therapy
- Cellular transport and secretion
- Health, Environment, Cognitive Aging
- Cardiac electrophysiology and arrhythmias
- Advanced Proteomics Techniques and Applications
- Cardiovascular Effects of Exercise
- Aortic Disease and Treatment Approaches
- Ubiquitin and proteasome pathways
- Bacteriophages and microbial interactions
- CAR-T cell therapy research
Cleveland Clinic
2024
Massachusetts General Hospital
2020-2023
Tufts Medical Center
2020-2021
Clinical Research Consortium
2021
Lenox Hill Hospital
2021
Stanford University
2021
Kyoto University
2021
University of Colorado Anschutz Medical Campus
2021
Harvard University
2021
University of California, San Francisco
2013-2016
Cardiogenic shock occurring in the setting of advanced heart failure (HF-CS) is increasingly common. However, recent studies have focused almost exclusively on acute myocardial infarction-related CS. We sought to define clinical, hemodynamic, metabolic, and treatment parameters associated with clinical outcomes among patients HF-CS, using data from Shock Working Group registry.Patients HF-CS were identified multicenter registry divided into 3 outcome categories assessed at hospital...
Background: Advanced age is associated with poor outcomes in cardiovascular emergencies. We sought to determine the association of age, use support devices and shock severity on mortality cardiogenic (CS). Methods: Characteristics CS patients included Cardiogenic Shock Work Group (CSWG) registry from 8 US sites between 2016 2019 were retrospectively reviewed. Patients subdivided by into quintiles Society for Cardiovascular Angiography & Interventions (SCAI) severity. Results:...
<ns4:p>Acute mechanical circulatory support (MCS) devices are widely used in cardiogenic shock (CS) despite a lack of high-quality clinical evidence to guide their use. Multiple exist across spectrum from modest complete support, and each is associated with unique risks. In this review, we summarize existing data on complications the three most acute MCS platforms: intra-aortic balloon pump (IABP), Impella systems, veno-arterial extracorporeal membrane oxygenation (VA-ECMO). We review...
Cardiac tumors of the left ventricle are rare, and cardiac magnetic resonance is preferred imaging tool for evaluation given superior tissue characterization. We present a case patient with arrhythmia ventricular mass that was ultimately diagnosed sarcoidosis, reminding us issue.
Background: Right ventricular failure (RVF) is associated with increased mortality among patients receiving left mechanical circulatory support (LV-MCS) for cardiogenic shock and requires prompt recognition management. Increased central venous pressure (CVP) an indicator of potential RVF. Objectives: We studied whether elevated CVP during LV-MCS acute myocardial infarction complicated by higher mortality. Methods: Between January 2014 June 2019, we analyzed hemodynamic parameters Impella...
Background: We describe the association between longitudinal hemodynamic changes and clinical outcomes in patients with cardiogenic shock (CS) receiving acute mechanical circulatory support devices (AMCS) at a single center. hypothesized that improved right atrial pressure is associated better survival CS. Methods: Retrospective analysis of from Tufts Medical Center received AMCS for Baseline characteristics invasive hemodynamics were collected, analyzed, correlated against outcomes....