A5081815123- Cardiac Arrest and Resuscitation
- Mechanical Circulatory Support Devices
- Cardiac Valve Diseases and Treatments
- Cardiac Structural Anomalies and Repair
- Infective Endocarditis Diagnosis and Management
- Diabetes Treatment and Management
- Respiratory viral infections research
- Acute Myocardial Infarction Research
- Heart Failure Treatment and Management
- Coronary Interventions and Diagnostics
- Cardiac Imaging and Diagnostics
- Influenza Virus Research Studies
- Viral gastroenteritis research and epidemiology
- Diabetes Management and Research
- Cardiac, Anesthesia and Surgical Outcomes
- Pharmaceutical Practices and Patient Outcomes
- Viral Infections and Vectors
- Antiplatelet Therapy and Cardiovascular Diseases
- Metabolism, Diabetes, and Cancer
- Hemodynamic Monitoring and Therapy
- Retinal Diseases and Treatments
- Atrial Fibrillation Management and Outcomes
- Adolescent Sexual and Reproductive Health
- Diabetes, Cardiovascular Risks, and Lipoproteins
- Central Venous Catheters and Hemodialysis
University of Utah
2019-2025
Newcastle University
2019-2023
Qiagen (United Kingdom)
2023
Northumbria Healthcare NHS Foundation Trust
2023
University of Oxford
2023
Prevention Group
2022
Massachusetts General Hospital
2022
Vanderbilt University Medical Center
2022
George Washington University
2022
Washington Center
2022
Neoplasms occur naturally in invertebrates but are not known to develop tapeworms. We observed nests of monomorphic, undifferentiated cells samples from lymph-node and lung biopsies a man infected with the human immunodeficiency virus (HIV). The morphologic features invasive behavior were characteristic cancer, their small size suggested nonhuman origin. A polymerase-chain-reaction (PCR) assay targeting eukaryotes identified Hymenolepis nana DNA. Although unrecognizable as tapeworm tissue,...
Background Multidisciplinary teams and regionalized care systems have been suggested to improve cardiogenic shock (CS) outcomes. We sought identify clinical factors associated with successful outcomes for patients developing CS at an outside healthcare facility (spoke) being transferred a quaternary medical center (hub). Methods Results Consecutive were evaluated (N=1162). Our study cohort comprised 412 spoke. primary end point was native heart survival (NHS) defined as discharge without...
Objective We aimed to analyse the incidence of prosthesis–patient mismatch (PPM) and elevated gradients after aortic valve in (ViV), evaluate predictors associations with clinical outcomes this adverse event. Methods A total 910 ViV patients were investigated. Elevated residual defined as ≥20 mm Hg. PPM was identified based on indexed effective orifice area (EOA), measured by echocardiography, patient body mass index (BMI). Moderate severe (cases) European Association Cardiovascular Imaging...
Background Rift Valley fever virus (RVFV) causes outbreaks of severe disease in livestock and humans throughout Africa the Arabian Peninsula. In people, RVFV generally a self-limiting febrile illness but subset individuals, it progresses to more serious disease. One manifestation is delayed-onset encephalitis that can be fatal or leave afflicted with long-term neurologic sequelae. order design targeted interventions, basic pathogenesis must better understood. Methodology/Principal Findings...
ABSTRACT Rapid identification of the causative pathogens central nervous system infections is essential for providing appropriate management and improving patient outcomes. The performance QIAstat-Dx Meningitis/Encephalitis (ME) Panel—a multiplex PCR testing platform—in detecting implicated in meningitis and/or encephalitis was evaluated using BioFire FilmArray ME Panel as a comparator method. This multicenter study analyzed 585 retrospective residual cerebrospinal fluid specimens 367...
Diagnosis of dengue virus (DENV) infection in fatal cases is challenging because the frequent unavailability blood or fresh tissues. For formalin-fixed, paraffin-embedded (FFPE) tissues immunohistochemistry (IHC) can be used; however, it may not as sensitive and serotyping possible. The application reverse transcription-polymerase chain reaction (RT-PCR) for detection DENV FFPE has been very limited. We evaluated autopsy 122 patients with suspected by flavivirus RT-PCR, sequencing, IHC. was...
BACKGROUND: Cardiogenic shock (CS) can stem from multiple causes and portends poor prognosis. Prior studies have focused on acute myocardial infarction-CS; however, decompensated heart failure (ADHF)-CS accounts for most cases. We studied patients suffering ADHF-CS to identify clinical factors, early in their trajectory, associated with a higher probability of successful outcomes. METHODS: Consecutive CS were evaluated (N=1162). who developed at our hospital (N=562). Primary end point was...
Three waves of human infection with H7N9 influenza viruses have concluded to date, but only within the first wave (isolated between March and September 2013) been extensively studied in mammalian models. While second- third-wave remain closely linked phylogenetically antigenically, even subtle molecular changes can impart critical shifts virulence. To determine if isolated from humans during 2013 2015 maintained phenotype identified among isolates, we assessed ability first-, second-, cause...
OBJECTIVES. The rhesus tetravalent rotavirus vaccine (RRV) was withdrawn from the routine program for childhood immunization in United States because of rare and unexpected occurrence intussusception 2-week period after administration first dose. METHODS. To search pathogenesis this association, we compared pathology surgical specimens infants who had reduction their intussusceptions within 2 weeks receiving (case patients; n = 8) with children surgery >2 (n 6) or never been immunized...
Abstract In countries where bancroftian filariasis is endemic, lymphedema of the leg a public health problem, particularly for women, who are disproportionately affected. We investigated effect basic management (hygiene, skin care, and lower limb movement elevation) on histologic features lymphedema. A total 118 skin-punch biopsies were collected from legs 91 patients enrolled in treatment clinic Léogâne, Haiti. Follow-up 27 ≈12 months later. Keratinocyte hyperproliferation, condensed dermal...
Cattle have been recognized as hosts for Amblyomma maculatum, the Gulf Coast tick, over 100 years. For nearly long, A. maculatum known to harbor spotted fever group Rickettsia (SFGR), now parkeri. However, human infection with R. parkeri was not documented until 2004. Results presented herein describe a laboratory and field study evaluating cattle natural history of in Mississippi. In study, seroconversion antigen occurred calves exposed by injection or feeding parkeri-infected two out six...