A5101692670- Bone Tissue Engineering Materials
- Dental Implant Techniques and Outcomes
- Bone Metabolism and Diseases
- Periodontal Regeneration and Treatments
- Graphene and Nanomaterials Applications
- Orthopaedic implants and arthroplasty
- Dental Trauma and Treatments
- MicroRNA in disease regulation
- Polymer Surface Interaction Studies
- Dental materials and restorations
- Antimicrobial Peptides and Activities
- Cell Adhesion Molecules Research
- Silk-based biomaterials and applications
- Bone health and treatments
- Electrospun Nanofibers in Biomedical Applications
- Titanium Alloys Microstructure and Properties
- Bone health and osteoporosis research
- Peptidase Inhibition and Analysis
- Electrohydrodynamics and Fluid Dynamics
- 14-3-3 protein interactions
- MXene and MAX Phase Materials
- Nanoparticle-Based Drug Delivery
- Advanced Sensor and Energy Harvesting Materials
- Solar-Powered Water Purification Methods
- 3D Printing in Biomedical Research
Xiamen Medical College
2015-2024
Xiamen University
2019-2024
Zhongshan Hospital of Xiamen University
2023
Fujian Medical University
2013-2015
Objective: To investigate the effect of sizes osteon-like concentric microgroove structures on osteoclastic differentiation macrophages titanium surfaces, and to provide reference for surface modification implants. Methods: The silicon wafers sputtered with were selected as control group (smooth specimens) four groups (concentric circles maximum diameter 200 μ m, minimum 20 spacing 10 or 30 μm, width microgrooves depth 5 μm) specimens (the total sample size in each was 27). C10-5 C10-10...
Titanium (Ti) implants with enhanced biocompatibility and antibacterial property are highly desirable characterized by improved success rates. In this study, titania nanotubes (TNTs) various tube diameters were fabricated on Ti surfaces through electrochemical anodization at 10, 30, 60 V (denoted as NT10, NT30, NT60, resp.). was also investigated used a control. NT10 diameter of 30 nm could promote the adhesion proliferation bone marrow mesenchymal stem cells (BMSCs) without noticeable...
Surface modification is an effective method to resolve the biocompatibility, mechanical, and functional issues of various titanium implant materials. Therefore, many researchers have modified surface promote osseointegration improve survival rate. In this study, we used photolithography construct concentric microgrooves with widths 10 μm depths μm, produce osteon-mimetic microgrooved that was further graphene oxide by silanization (GO-CMS). The had great biocompatibility promoted...
Abstract Graphene composites possess great application potential in various fields including flexible electrodes, wearable sensors and biomedical devices owing to their excellent mechanical electrical properties. However, it remains challenging fabricate graphene composites-based with high consistency due the gradual aggression effect of during fabrication process. Herein, we propose a method for one-step fabricating graphene/polymer composite-based from graphite/polymer solution by using...
Titanium (Ti) implants with long-term antibacterial ability and good biocompatibility are highly desirable materials that can be used to prevent implant-associated infections. In this study, titania nanotubes (TNTs) were synthesized on Ti surfaces through electrochemical anodization. Octenidine dihydrochloride (OCT)/poly(lactic-co-glycolic acid) (PLGA) was infiltrated into TNTs using a simple solvent-casting technique. OCT/PLGA-TNTs demonstrated sustained drug release maintained the...
Material surface micromorphology can modulate cellular behavior and promote osteogenic differentiation through cytoskeletal rearrangement. Bone reconstruction requires precise regulation of gene expression in cells, a process governed by epigenetic mechanisms such as histone modifications, DNA methylation, chromatin remodeling. We constructed osteon-mimetic concentric microgrooved titanium surfaces with different groove sizes cultured bone marrow-derived mesenchymal stem cells (BMSCs) on the...
To investigate the physical properties of modified microgroove (MG) and antibacterial nanocoated surfaces. In addition, biological interactions surfaces with human gingival fibroblasts (HGFs) activity against Porphyromonas gingivalis were studied.The titanium nitride (TiN) silver (Ag) coatings deposited onto smooth MG using magnetron sputtering. A surface (Ti-S) was used as control. The physicochemical including morphology, roughness, hydrophilicity characterized scanning electron...
The aim of this study was to evaluate the effects collagen modification on osteogenic performance different surface-modified titanium, including alkaline etching, etching followed by silanization, and dopamine modification. proliferation, adhesion, differentiation abilities MC3T3-E1 cells surfaces with were analyzed compared.
Implant surface designs have advanced to address challenges in oral rehabilitation for healthy and compromised bone. Several studies analyzed the effects of altering material surfaces on osteogenic differentiation. However, crucial role osteoclasts osseointegration has often been overlooked. Overactive can compromise implant stability. In this study, we employed a silanization method alter pure titanium produce loaded with antimicrobial peptide GL13K that enhanced biocompatibility. Pure...
Objective: To study the effects of titania nanotubes with three different diameters on human gingival fibroblast (HGF). Methods: Three groups specimens were prepared. Titania 30, 100, and 200 nm synthesized titanium surfaces through electrochemical anodization at 10, 60 V, respectively. Specimens assigned into according to diameter nanotubes. Pure smooth without any treatment was set as control group. HGF seeded surface samples. The cell morphology observed immunofluorescence staining after...
Objective: To study the effect of microgroove surface modification titanium and zirconia on biological behavior gingival fibroblasts in order to find suitable materials for transmucosal part dental implant. Methods: Twenty specimens were divided into four groups: smooth (Ti-S), (ZC-S), (Ti-MG) (ZC-MG) (five each group). Microgroove surfaces was carried out by using fine machining chip system last two groups. The width groove ridge 60 μm, depth 10 μm. morphologies (the depth) observed...
Material surface micromorphology can modulate cellular behavior and promote osteogenic differentiation through cytoskeletal rearrangement. Bone reconstruction requires precise regulation of gene expression in cells, a process governed by epigenetic mechanisms such as histone modifications, DNA methylation, chromatin remodeling. We constructed concentric microgrooved titanium surfaces with different groove sizes cultured bone marrow-derived mesenchymal stem cells (BMSCs) on the material to...