Li Li

ORCID: 0000-0002-4227-3424
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Research Areas
  • Acute Kidney Injury Research
  • Cardiac Arrest and Resuscitation
  • Dialysis and Renal Disease Management
  • Sepsis Diagnosis and Treatment
  • Renal and Vascular Pathologies
  • Neurological Disease Mechanisms and Treatments
  • Trauma and Emergency Care Studies
  • Chronic Kidney Disease and Diabetes
  • Trauma, Hemostasis, Coagulopathy, Resuscitation
  • Head and Neck Cancer Studies
  • Medical Research and Treatments
  • Cardiac, Anesthesia and Surgical Outcomes
  • Dermatology and Skin Diseases
  • Advanced Technologies in Various Fields
  • Analytical Chemistry and Chromatography
  • Regional Development and Environment
  • Renal function and acid-base balance
  • Immune Response and Inflammation
  • Diabetic Foot Ulcer Assessment and Management
  • Central Venous Catheters and Hemodialysis
  • Ginger and Zingiberaceae research
  • Cardiac Health and Mental Health
  • Autopsy Techniques and Outcomes
  • Peripheral Neuropathies and Disorders
  • Hydrogels: synthesis, properties, applications

Jiangsu Province Hospital
2017-2024

Nanjing Medical University
2017-2024

Hebei Medical University
2022-2024

Fujian Medical University
2023

Hainan Medical University
2020-2022

Hainan General Hospital
2021

Shantou University
2021

Yue Bei People's Hospital
2021

Sichuan University
2016-2021

West China Hospital of Sichuan University
2021

Importance Despite the expansion of published electronic alerts for acute kidney injury (AKI), there are still concerns regarding their effect on clinical outcomes patients. Objective To evaluate AKI alert combined with a care bundle and patients hospital-acquired AKI. Design, Setting, Participants This single-center, double-blind, parallel-group randomized trial was conducted in tertiary teaching hospital Nanjing, China, from August 1, 2019, to December 31, 2021. The inclusion criteria were...

10.1001/jamanetworkopen.2023.51710 article EN cc-by-nc-nd JAMA Network Open 2024-01-19

Acute kidney injury (AKI) is one of the most common organ dysfunction in sepsis, and increases risk unfavourable outcomes. Renal replacement therapy (RRT) predominant treatment for sepsis-associated AKI (SAKI). However, to date, no prospective randomised study has adequately addressed whether initiating RRT earlier will attenuate renal improve outcome sepsis. The objective trial compare early strategy with delayed on outcomes patients SAKI intensive care unit (ICU).This a large-scale,...

10.1136/bmjopen-2020-040718 article EN cc-by-nc BMJ Open 2021-02-01

Abstract Objective This study inventively combines epidermal growth factor receptor (EGFR) expression of the primary lesion and standardized uptake value (SUV) positron emission tomography computed (PET/CT) to predict prognosis nasopharyngeal carcinoma (NPC). aimed evaluate predictive efficacy maximum standard (SUVmax) EGFR for treatment failure in patients with NPC. Methods retrospective reviewed results pretreatment 18 F-FDG PET/CT 313 Time-dependent receiver operator characteristics was...

10.1186/s13014-023-02231-6 article EN cc-by Radiation Oncology 2023-02-22

Objective There are controversial opinions on anticoagulation for continuous venovenous hemofiltration (CVVH) in patients with liver failure (LF) and increased bleeding risk. Therefore, we conducted a retrospective study to evaluate the efficacy safety of regional citrate (RCA) versus no-anticoagulation CVVH these patients. Methods The included were divided into RCA group according strategy they accepted CVVH. Filter lifespan, bleeding, accumulation, catheter occlusion, totCa/ionCa ratio...

10.1371/journal.pone.0232516 article EN cc-by PLoS ONE 2020-05-05

Abstract Cardiac rehabilitation program is well‐established but the Rehabilitation After Myocardial Infarction Trial (RAMIT) reported that it does not affect mortality and morbidity of patients after myocardial infarction during follow‐up period. The objectives study were to compare functional walking capacity, risk factor control, morbidities in for cardiac (exercise + education), exercise only, usual care among with coronary artery disease. A total 492 male female (age range: 45–73 years)...

10.1002/prp2.711 article EN cc-by-nc Pharmacology Research & Perspectives 2021-01-17

Cardiorenal syndrome (CRS) is a group of disorders in which heart or kidney dysfunction worsens each other. This study aimed to explore the improvement effect nicorandil on cardiorenal injury patients with type I CRS. Patients coronary disease complicated CRS were enrolled. Based conventional treatment, prospectively randomized into treatment and group, was treated 24 mg/d intravenously for 1 week. Fasting peripheral venous blood serum urine collected before at end treatment. An automatic...

10.1097/fjc.0000000000001117 article EN cc-by-nc-nd Journal of Cardiovascular Pharmacology 2021-09-29

Acute kidney injury (AKI) is a common disease, but diagnosis usually delayed or missed in hospitalized patients. The aim of this study was to investigate the impact under-recognition AKI (beyond 3 days after onset) on short-time prognosis. Of 785 patients with and 616 timely-recognition were propensity matched 1:1 ratio. two groups, total 482 (241:241), comparable baseline covariates. Under-recognition not associated 30-day all-cause mortality logistic regression model covariate adjustment...

10.1038/s41598-018-33103-9 article EN cc-by Scientific Reports 2018-10-05

Introduction: Acute kidney injury has been identified as a common complication of cardiac surgery. To date, the effect time interval from coronary angiography to surgery on postoperative acute is still controversial. The aim this study was investigate relationship between timing and associated injury. Methods: Eight hundred thirteen patients who underwent successively January 2017 December 2018 were included in retrospective cohort study. We applied multivariate logistic regression,...

10.3389/fmed.2021.619210 article EN cc-by Frontiers in Medicine 2021-04-15

ABSTRACT Morinidazole belongs to the category of third‐generation nitroimidazole antibacterial drugs. In course morinidazole production, mother liquor from recrystallization process was subjected analysis for identification and detection eight process‐related impurities through high‐performance liquid chromatography (HPLC). The ( Imp‐A , Imp‐B Imp‐C Imp‐D Imp‐E Imp‐F Imp‐G Imp‐H ) included three new that were previously unreported one potential genotoxic impurity ). Purity separation carried...

10.1002/sscp.202400133 article EN Separation Science Plus 2024-11-24

Background Acute kidney injuries are common in the medical intensive care unit. Generally, intravenous normal saline is administered critically ill patients but it associated with acute injury. Current knowledge of chloride and its effect on physiological functions limited. The objectives study were to compare safety chloride-restrictive fluid administration against that chloride-liberal regarding injuries. Methods Data RIFLE (risk, injury, failure, loss, end-stage renal failure) categories,...

10.1111/ijcp.13972 article EN International Journal of Clinical Practice 2020-12-26

Objective Acute kidney injury (AKI) is common but usually under-diagnosed in hospitalized patients, of the impact which on patients still unclear. The paper was aimed to investigate delayed recognition AKI short-time prognosis through a propensity score matched study. Methods From Oct 2013 Sep 2014, 1401 adult with First Affiliated Hospital Nanjing Medical University were divided into group and timely-diagnosed according matching (1∶1) without replacement method. Primary endpoint...

10.3760/cma.j.issn.1001-7097.2017.05.002 article EN 2017-05-15

A total of 200 surgeons, 55 operating room nurses, 220 patients and anesthesiologists from hospitals different grades (6 grade tertiary hospitals, 2 B secondary 1 hospital)in cities completed questionnaires.The main content investigated included nurses patients′ attitudes towards about appellation, educational requirements(doctorate, master′s degree, bachelor′s associate′s degree) qualification recognition anesthesiologists′ acceptance their appellation(satisfied, indifferent, obnoxious,...

10.3760/cma.j.issn.0254-1416.2017.01.005 article EN 2017-01-20
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