Xiaohong Zhan

ORCID: 0009-0002-1106-2875
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About
Contact & Profiles
Research Areas
  • Oral and Maxillofacial Pathology
  • Pancreatic and Hepatic Oncology Research
  • Inflammatory Biomarkers in Disease Prognosis
  • Hedgehog Signaling Pathway Studies
  • MicroRNA in disease regulation
  • Sarcoma Diagnosis and Treatment
  • Tumors and Oncological Cases
  • Cancer Cells and Metastasis
  • Esophageal Cancer Research and Treatment
  • Lung Cancer Diagnosis and Treatment
  • Bone Tumor Diagnosis and Treatments
  • Hernia repair and management
  • Cancer Mechanisms and Therapy
  • Head and Neck Cancer Studies
  • Ear and Head Tumors
  • Cutaneous lymphoproliferative disorders research
  • Extracellular vesicles in disease
  • Pelvic and Acetabular Injuries
  • Infective Endocarditis Diagnosis and Management
  • Salivary Gland Tumors Diagnosis and Treatment
  • Wnt/β-catenin signaling in development and cancer
  • Hepatocellular Carcinoma Treatment and Prognosis
  • Intensive Care Unit Cognitive Disorders
  • 14-3-3 protein interactions
  • Acute Myeloid Leukemia Research

Qingdao University
2017-2025

Affiliated Hospital of Qingdao University
2017-2025

Second Hospital of Shandong University
2022

Southwest University of Science and Technology
2021

Hainan Medical University
2021

Hainan General Hospital
2021

First People's Hospital of Jingzhou
2019

Anhui Medical University
2016-2017

Anhui Provincial Hospital
2016-2017

Shandong University
2017

Although sialoblastoma (SBL) is defined as a low-grade malignant salivary gland anlage neoplasm in the 2022 World Health Organization (WHO) Classification of Head and Neck Tumors, its histology, genetics, behavior remain controversial due to rarity tumor. Here, we performed first comprehensive clinical, histologic, molecular analyses 8 SBLs better understand their pathogenesis prognosis. This cohort consisted 5 boys 3 girls, with ages ranging from birth 9 years at diagnosis. Tumors occurred...

10.1097/pas.0000000000002356 article EN The American Journal of Surgical Pathology 2025-01-14

Lipoblastoma-like tumors (LLTs) are uncommon lipogenic neoplasms that predominantly occur in the vulva of female individuals. This study presents a novel case LLT located on tongue with an IDH1 mutation. Both site occurrence and molecular alterations reported for first time. A 65-year-old patient presented to hospital 1 month ago incidental finding multinodular mass at right lingual margin. We performed incision along outer edge completely excised it 0.5 cm beyond its periphery. The final...

10.1002/hed.28104 article EN Head & Neck 2025-02-10

The present study aimed to investigate the role and underlying mechanisms of microRNA16 (miR-16) on proliferation, apoptosis invasion glioma cells. cell models miR-16 upregulation Negative control group (NC group) were built. functions different groups detected by colony formation assay, transwell chamber cycle experiments. intracranial orthotopic transplantation animal built groups: agomir group, antagomir their NC group. expressions miR-16, Wip1, ATM p53 measured qRT-PCR, western blot...

10.18632/oncotarget.18510 article EN Oncotarget 2017-06-16

Background and study aims: Implantation of iodine-125 (125I) seeds under the guidance endoscopic ultrasonography (EUS) has been proved to be a safe alternative treatment option for advanced pancreatic cancer. The main purpose this was evaluate feasibility safety EUS-guided radiation celiac ganglia with125I in porcine model.

10.1055/s-0028-1119588 article EN Endoscopy 2009-04-01

Keratocystoma of the parotid gland is a rare benign salivary tumor. In 2022, World Health Organization added keratocystoma to classification tumors. Recently, our hospital encountered case involving 2-year-old child, making this youngest patient reported date. We excised part and lesion under general anesthesia while preserving facial nerve. There was no local recurrence during 1-year follow-up period after surgery. Despite its rarity, it essential consider possibility distinguish from other...

10.1177/01455613241287012 article EN cc-by-nc Ear Nose & Throat Journal 2024-10-14

The present study was designed to investigate the prognostic significance of preoperative sensitive-modified Glasgow score (S-mGPS) and its superiority in esophageal squamous cell carcinoma (ESCC). Clinicopathologic characteristics, albumin C-reactive protein (CRP) levels were retrospectively collected 442 patients who underwent transthoracic esophagectomy. S-mGPS calculated before surgery based on optimal cutoff values 45.6 g/L for 10.0 mg/L CRP. 360, 74 8 cases assigned an mGPS 0, 1 2,...

10.18632/oncotarget.11268 article EN Oncotarget 2016-08-12

Abstract Cardiac rehabilitation program is well‐established but the Rehabilitation After Myocardial Infarction Trial (RAMIT) reported that it does not affect mortality and morbidity of patients after myocardial infarction during follow‐up period. The objectives study were to compare functional walking capacity, risk factor control, morbidities in for cardiac (exercise + education), exercise only, usual care among with coronary artery disease. A total 492 male female (age range: 45–73 years)...

10.1002/prp2.711 article EN cc-by-nc Pharmacology Research & Perspectives 2021-01-17

The present study was to establish a prognostic indicator based on preoperative fibrinogen and C-reactive protein (CRP) (FC score) in esophageal squamous cell carcinoma (ESCC). Clinicopathologic characteristics, plasma serum CRP levels were reviewed patients who underwent transthoracic esophagectomy. optimal cut-off value for defined as 4.0 g/dL 10.0 mg/L according previous reports. Patients with elevated assigned score of 2, those only one these two abnormalities allocated 1, neither the 0....

10.18632/oncotarget.11145 article EN Oncotarget 2016-08-09

Abstract Background Breast cancer is the most common malignant tumor among women worldwide. GREB1L a protein-coding gene. Previous studies have shown that plays vital role in lung and gastric adenocarcinoma. Currently, there no relevant report about its breast cancer. Methods The Cancer Genome Atlas database was used to compare expression level of between normal tissues. TISIDB website for prognosis analysis. LinkedOmics predict potential biological mechanism Immunohistochemistry detect...

10.1186/s40001-023-01483-y article EN cc-by European journal of medical research 2023-11-14

Abstract Objectives Lymph node metastasis (LNM) is a pivotal determinant that influences the treatment strategies and prognosis for oropharyngeal squamous cell carcinoma (OPSCC) patients. This study aims to establish verify deep learning (DL) radiomics model prediction of LNM in OPSCCs using contrast-enhanced computed tomography (CECT). Methods A retrospective analysis included 279 OPSCC patients from 3 institutions. CECT images were used handcrafted (HCR) DL feature extraction....

10.1093/dmfr/twae051 article EN Dentomaxillofacial Radiology 2024-09-13

The diagnosis and treatment of head neck undifferentiated carcinoma (HNUC) present significant challenges. Herein, we the case a patient with advanced HNUC who underwent conversion surgery following combination pembrolizumab nimotuzumab. During therapy, histological transformation from to sarcomatoid was detected at primary site. This not only highlights potential immune combination-targeted therapy reduce tumour burden increase surgical options for patients, but also reveals complex...

10.3389/fimmu.2024.1484915 article EN cc-by Frontiers in Immunology 2024-10-24

Alveolar soft part sarcoma (ASPS) is an extremely rare malignant sarcoma, accounting for less than 1% of all soft-tissue sarcomas. However, limited information available on multimodal imaging [computed tomography (CT), magnetic resonance (MRI), and positron emission computed tomography/computed (PET/CT)] ASPS.This study reports a case 35-year-old female patient with ASPS the left thigh lung metastasis. The presented 1-year history palpable mass in lower extremity, which exhibited rapid...

10.12998/wjcc.v8.i15.3349 article EN World Journal of Clinical Cases 2020-08-05

Primary diffuse cutaneous large B-cell lymphoma, leg type (PCDLBCL-LT), usually affecting one or both lower legs, with a 5-year disease-free survival rate of less than 60%. Solitary facial lesions are extremely rare. Our report is about 93-year-old woman whose clinical examination revealed 4 cm × 5 3 mass soft texture and smooth margins on the right side her cheek. Immunohistochemical analyses were consistent diagnosis PCDLBCL-LT. The surgical method for this patient was: extensive resection...

10.1177/01455613231202192 article EN cc-by-nc Ear Nose & Throat Journal 2023-09-30

The treatment for early-stage non-small cell lung cancer is primarily surgical. However, the optimal extent of mediastinal lymph node resection remains to be determined. aim current study investigate effect a pulmonary wedge on aged patients with cancer.A total 15 over 70 years were treated via video-assisted thoracoscopic surgery (VATS) and sampling from June 2004 February 2008. Mediastinal included stations 2R, 4R, 8 9 right-sided cancers 5, 6, left-sided cancers.VATS peripheral are...

10.3779/j.issn.1009-3419.2012.01.10 article EN DOAJ (DOAJ: Directory of Open Access Journals) 2012-01-01

Fast track surgery(Frs) is an idea and theory which has been highlighted by more clinic doctors scholars, widely used in the surgical operations recently. ~TS greatly changed mode of therapy, ameliorated velocity rehabilitation prognosis after operation, improved quali- ty life therapeutic effect. We reviewed application FTS surgery this article. Key words: fast surgery; 

10.3760/cma.j.issn.1673-4203.2008.08.012 article EN 国际外科学杂志 2008-08-31

Abstract Background Breast cancer is a malignant tumor with the highest incidence among women in world. GREB1L protein coding gene. Previous studies have shown that played an important role lung adenocarcinoma and gastric adenocarcinoma. Currently, there no relevant report about its breast cancer. Methods The Cancer Genome Atlas database was used to compare expression level of GREB1L; TISIDB website for prognosis analysis; LinkedOmics predict potential biological mechanism cancer;...

10.21203/rs.3.rs-2220353/v1 preprint EN cc-by Research Square (Research Square) 2022-11-04
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