A5049590575- BRCA gene mutations in cancer
- Cancer survivorship and care
- Nutrition, Genetics, and Disease
- Chemokine receptors and signaling
- Adipokines, Inflammation, and Metabolic Diseases
- Gestational Diabetes Research and Management
- Cancer-related cognitive impairment studies
- Chemotherapy-induced cardiotoxicity and mitigation
- Atherosclerosis and Cardiovascular Diseases
- Complementary and Alternative Medicine Studies
- Child and Adolescent Health
- Inflammation biomarkers and pathways
- RNA Interference and Gene Delivery
- Homicide, Infanticide, and Child Abuse
- Cancer Treatment and Pharmacology
- Lymphatic System and Diseases
- Ultrasound Imaging and Elastography
- Ultrasound and Hyperthermia Applications
- Childhood Cancer Survivors' Quality of Life
- Pregnancy and preeclampsia studies
- Cardiac Imaging and Diagnostics
- Family Support in Illness
- Palliative Care and End-of-Life Issues
- Breastfeeding Practices and Influences
- Birth, Development, and Health
Mayo Clinic
2012-2025
Carol Davila University of Medicine and Pharmacy
2023-2024
Mayo Clinic in Arizona
2011-2024
Mayo Clinic Hospital
2023-2024
WinnMed
2013-2023
Clinical Emergency Hospital Bucharest
2017-2023
Mayo Clinic in Florida
2012-2023
Spitalul Clinic de Urgenta Sfantul Ioan
2021
"Dunarea de Jos" University of Galati
2021
Romanian Academy
2011-2016
To determine the sensitivity and specificity of genetic testing criteria for detection germline pathogenic variants in women with breast cancer.
Pilates has been advocated for rehabilitation of breast cancer survivors despite little scientific evidence. The authors this article have examined the feasibility a program in postmastectomy and impact on physical psychological parameters. Fifteen were recruited one-arm study 12 weeks exercises. assessed recruitment, adherence, attrition, measured changes shoulder neck range motion, posture, height, arm volume, quality life, mood, body image from pre- to postintervention. Of 26 eligible...
Survivors of breast cancer are faced with a multitude medical and psychological impairments during after treatment throughout their lifespan. Physical exercise has been shown to improve survival recurrence in this population. Mind-body interventions combine light-moderate intensity physical mindfulness, thus having the potential both sequelae treatments. We conducted review mindfulness-based which included yoga, tai chi chuan, Pilates, qigong, survivors. Among interventions, yoga was...
The present study reports fullerene conjugates that act as efficient binders of double stranded DNA (dsDNA) into cytofriendly polyplexes. are designed to generate dendrimeric structures, having C60 the core and bearing linear or branched PEI polyethyleneglycol (PEG) arms (∼2 kDa). Simple reproducible synthesis pathways provided C60-PEI C60-PEG-PEI conjugates. They were able bind plasmidic dsDNA they form particulate polyplexes 50 200 nm in diameter. resulted toggle between anionic cationic...
Abstract Objectives To prepare and characterize in vitro vivo lipid nanoemulsions (LN) loaded with curcumin (Cm) functionalized a cell-penetrating peptide. Methods Curcumin-loaded (CmLN) nona-arginine peptide (R9-CmLN) have been obtained, characterized optimized for size, entrapment efficiency Cm release. The interaction of R9-CmLN human endothelial cells (HEC) was investigated using cultured EA.hy926 cells, biodistribution studies were performed C57BL6 mice. Key findings When used...
Summary The major complication of diabetes mellitus is accelerated atherosclerosis that entails an inflammatory process, in which fractalkine and monocyte chemotactic protein-1 (MCP-1) play a key role.We investigated the effect diabetes-associated high glucose (HG) on these chemokines signalling mechanisms involved human aortic smooth muscle cells (SMC). Exposure SMC to HG resulted increase MCP-1 expression activated mitogen-activated protein kinase (MAPK) pathway, process associated with...
Abstract Background Low specificity in current breast imaging modalities leads to increased unnecessary follow-ups and biopsies. The purpose of this study is evaluate the efficacy combining quantitative parameters high-definition microvasculature (HDMI) 2D shear wave elastography (SWE) with clinical factors (lesion depth age) for improving lesion differentiation. Methods In prospective study, from June 2016 through April 2021, patients lesions identified on diagnostic ultrasound recommended...
Purpose To investigate the effects of macrocalcifications and clustered microcalcifications associated with benign breast masses on shear wave elastography (SWE). Methods SuperSonic Imagine (SSI) comb-push ultrasound (CUSE) were performed three sets phantoms to how calcifications different sizes distributions influence measured elasticity. demonstrate effect in vivo, female patients mammographically-identified evaluated by CUSE. Results Apparent maximum elasticity (Emax) estimates resulting...
Inflammation is a common process associated with numerous vascular pathologies. We hypothesized that targeting the inflamed endothelium by coupling peptide high affinity for P-selectin to surface of dexamethasone-loaded lipid nanoemulsions will highly increase their specific binding activated endothelial cells (EC) and reduce cell activation. developed characterized directed towards (PLN-Dex) monitored anti-inflammatory effects in vitro using cultured EC (EA.hy926 cells) vivo mouse model...
Background: Breast cancer diagnosis and treatment affect quality of life stress are associated with fatigue. Meditation interventions effective strategies for patients breast but often limited by poor access, high cost, substantial time commitment, adherence. In this feasibility study, we investigated the use a portable, wearable, electroencephalographic device guided meditation practices during period from until 3 months after surgical treatment. Methods: We enrolled women (age = 20-75...
Abstract Purpose To assess the feasibility of an app-based, electronic health record (EHR)-integrated, interactive care plan (ICP) for breast cancer (BC) survivors. Methods A single-arm pilot study was conducted with female BC ICP tasks included quarterly quality life (QOL) questionnaire; monthly assessments fatigue, insomnia, sexual dysfunction, hot flashes, and recurrence symptoms; daily activity reminders. Embedded decision trees escalated symptoms to providers. On-demand education...