A5103001380- Inflammatory Bowel Disease
- Microscopic Colitis
- Eosinophilic Esophagitis
- Pregnancy and Medication Impact
- Gastrointestinal motility and disorders
- Complementary and Alternative Medicine Studies
- Tuberculosis Research and Epidemiology
- Diagnosis and treatment of tuberculosis
- Acute Lymphoblastic Leukemia research
- Autoimmune and Inflammatory Disorders
- Helicobacter pylori-related gastroenterology studies
- Mycobacterium research and diagnosis
- Immunodeficiency and Autoimmune Disorders
- Reproductive System and Pregnancy
- Diverticular Disease and Complications
- Celiac Disease Research and Management
- IL-33, ST2, and ILC Pathways
- Gut microbiota and health
- Autoimmune and Inflammatory Disorders Research
- Anorectal Disease Treatments and Outcomes
- Clostridium difficile and Clostridium perfringens research
- Diet and metabolism studies
- Fibromyalgia and Chronic Fatigue Syndrome Research
- Venous Thromboembolism Diagnosis and Management
- Adolescent and Pediatric Healthcare
Medical University of Vienna
2016-2025
Universitätszahnklinik Wien
2020
Moser (Czechia)
2018
Osaka National Hospital
2015
St. Pölten University of Applied Sciences
2015
Vienna General Hospital
1999-2013
Mount Sinai Hospital
2013
American Gastroenterological Association
2010
University of Vienna
1996-2008
Tricoci University of Beauty Culture
2005
Objective There is evidence of an interaction between psychological factors and activity inflammatory bowel disease (IBD). We examined the influence depressive mood associated anxiety on course IBD over a period 18 months in cohort patients after episode active disease. Methods In this prospective, longitudinal, observational study, 60 (37 women 23 men) with clinically inactive (Crohn disease, n = 47, 78%; ulcerative colitis, 13, 22%) were enrolled flare Psychological status, health-related...
OBJECTIVES: Fecal microbiota transplantation (FMT) from healthy donors, which is an effective alternative for treatment ofClostridium difficile–associated disease, being considered several disorders such as inflammatory bowel irritable syndrome, and metabolic syndrome. Disease remission upon FMT thought to be facilitated by efficient colonization of donor microbiota, but knowledge the composition temporal stability patient after lacking. METHODS: Five patients with moderately severely active...
Summary Background : Antibiotics and thiopurines have been employed in the management of fistulizing Crohn's disease, although evidence their efficacy is rare. Aim To evaluate, a prospective, open‐label study, influence antibiotics azathioprine on clinical outcome perianal fistulas patients with disease. Methods Fifty‐two entered starting an 8‐week regimen ciprofloxacin (500–1000 mg/day) and/or metronidazole (1000–1500 mg/day). Seventeen had already received daily (2–2.5 mg/kg) at enrolment,...
Background The impact of pregnancy on the course IBD is still controversial. Aim To investigate and to search for factors with potential remission. Methods Pregnant women from 12 European countries were enrolled between January 2003 December 2006 compared at conception (1:1) nonpregnant women. Data disease prospectively collected each trimester during in postpartum (6 months) using a standardised questionnaire. Results A total 209 pregnant included: 92 Crohn's (CD; median age 31 years, range...
Gut-directed hypnotherapy (GHT) in individual sessions is highly effective the treatment of irritable bowel syndrome (IBS). This study aimed to assess long-term effect GHT group for refractory IBS.A total 164 patients with IBS (Rome-III-criteria) were screened, and 100 usual randomized 1:1 either supportive talks medical (SMT) or SMT (10 weekly within 12 weeks). The primary end point was a clinically important improvement on several dimensions daily life (assessed by impact scale) after...
Irritable bowel syndrome (IBS) is associated with alterations along the brain-gut-microbiota axis. Previous studies have suggested a parallel segregation of microbial features and psychological burden in IBS. This study aimed at exploring correlates distress patients IBS.Forty-eight IBS (Rome III criteria, M (SD) age = 42 (15) years, 35 female, 25 diarrhea-dominant, 5 constipation-dominant, 18 alternating-type IBS) were assessed for clinical variables validated questionnaires, fecal samples...
To investigate the clinical relevance of interleukin-6 (IL-6) serum levels in patients with Crohn's disease (CD), single point IL-6 measurements sera from consecutive CD and healthy donors (HD), as well longitudinal during course steroid therapy for active were performed. Patients steroid-induced remission followed until relapse.One hundred thirty-six without or other immunosuppressive treatment within 2 months surgical procedures 3 before study entry investigated; 63 enrolled into follow-up...
Recommendations on breastfeeding under thiopurines are inconsistent due to limited data.To assess the risk of infections in offspring breastfed by mothers receiving azathioprine (AZA) for inflammatory bowel disease (IBD).Babies, who were from their treated either with or without AZA included a local pregnancy-registry. Women asked structured personal interview general development, infections, hospitalisations and vaccinations offspring.A group 11 taking (median 150 mg/d) during pregnancy...
OBJECTIVES: Anemia is a common complication of inflammatory bowel disease (IBD) and iron deficiency (ID) its predominant cause. Therefore, oral intravenous replacements are widely used. This study was performed to evaluate the frequency timing anemia ID recurrence after successful treatment cycle. METHODS: Medical records patients who had received sucrose with or without erythropoietin (EPO) in one three prospective clinical trials that been conducted at our center (Ann Intern Med 1997,...
Patients with inflammatory bowel disease (IBD) are at increased risk of venous thromboembolism (VTE), but data on frequency, site thrombosis and factors limited. We sought to determine prevalence, incidence as well location clinical features first VTE among IBD patients.We evaluated a cohort 2811 patients for history symptomatic, objectively confirmed VTE, recruited from 14 referral centers. before diagnosis or cancer were excluded. Incidence rates calculated based person-years end...
Infliximab (IFX) has tremendously enriched the therapy of inflammatory bowel diseases (IBD) and other immune mediated diseases. Although efficacy IFX was undoubtedly proven during last decade numerous publications have also caused various safety concerns. To summarize immense information concerning adverse events issues Austrian Society Gastroenterology Hepatology launched this evidence based consensus on safe use which covers following topics: infusion reactions immunogenicity, skin...
An increasing and early-onset use of immunosuppressives biologics has become more frequently seen among patients with inflammatory bowel diseases (IBD) rheumatic disorders. Many women in their childbearing years currently receive such medications, some them an interdisciplinary setting. questions arise already pregnant or wishing to conceive respect continuing discontinuing treatment, the risks borne by newborns mothers long-term safety. Together Austrian Society Rheumatology Rehabilitation,...
Background and Study Aims: Strictures are a substantial cause of morbidity in patients with Crohn's disease. Endoscopic balloon dilation is therapeutic option limited strictures to avoid intestinal surgery, although there have been few reports regarding the long-term outcome. Patients Methods: Balloon was scheduled for 46 (26 women, 20 men; median age 34) Crohn's-associated symptomatic radiographically confirmed stenosis. The study plan envisaged up four consecutive treatments within first 2...
Background and Study Aims: It is generally believed that making a correct histological diagnosis of colitis at colonoscopy requires segmental mucosal biopsies, information on the endoscopic features, clinical data. This prospective study was carried out to determine essential parameters required for an accurate colitis. Patients Methods: Two hundred consecutive patients with suspected or established who underwent were prospectively examined. A double biopsy taken macroscopic site typical...
Psychological distress is frequent in inflammatory bowel disease (IBD). Whether there a need for psychological interventions unknown. This study investigated the quantity and quality of IBD as compared to rheumatoid arthritis (RA).In all, 302 patients with 109 RA answered ADAPT questionnaire, assessing psychosomatic support (physicians support) psychotherapy, hospital anxiety depression scale, SF-36, questionnaire on social (SOZU-K22), Rating Form Patient Concerns (IBD only). Detailed...
Self-reported outcome instruments in health research have become increasingly important over the last decades. Occupational therapy interventions often focus on occupational balance. However, to measure balance are scarce. The aim of study was therefore develop a generic self-reported instrument assess based experiences patients and healthy people including an examination its psychometric properties. We conducted qualitative analysis life stories 90 with without chronic autoimmune diseases...
Abstract Background Bowel urgency is one of the most bothersome symptoms in patients with Ulcerative colitis (UC) and Crohn´s disease (CD). However, only recently attention has been focused on this symptom data associated factors, especially CD, scarce. The Health Outcome Observatory (H2O) project aims to standardize facilitate collection reported outcomes (PROs) clinical by developing multi-stakeholder agreed Core Sets (COS) including for inflammatory bowel (IBD). present study describes...
Summary Background: Conventional non‐steroidal anti‐inflammatory drugs have been associated with an increased risk of exacerbation inflammatory bowel disease. Aim: To evaluate, in a prospective, open‐label study, the safety and efficacy 20‐day regimen selective cyclo‐oxygenase‐2 inhibitor, rofecoxib, 12.5–25 mg/day, disease patients peripheral arthropathy and/or arthritis. Methods: Patients clinically inactive to mild joint pain score at least two points on scale ranging from zero (none)...
Screening for latent tuberculosis (LTB) including chest x-ray, tuberculin skin test (TST), and facultative whole blood interferon-γ assay (IGRA) is part of routine management in inflammatory bowel disease (IBD) patients before starting therapy with tumor necrosis factor (TNF)-α inhibitors. However, immunomodulators (IM) TST IGRA might show limitations.We aimed to evaluate the results from an (QuantiFERON-TB Gold Tube) as well their concordance 208 consecutive IBD indications anti-TNF-α...
Smoking and a lack of immunosuppressive (IS) therapy are considered risk factors for intestinal surgery in Crohn's disease (CD). Good evidence the latter is lacking. The objective this study was to evaluate impact thiopurine treatment on surgical recurrence patients after first resection CD its possible interaction with smoking.Data 326 were retrieved retrospectively, subjects grouped according their postoperative exposure thiopurines. Treatment either azathioprine (AZA) or 6-mercaptopurine...
Cyclosporine (CsA) or infliximab (IFX) are used as rescue therapies in steroid-refractory, severe attacks of ulcerative colitis (UC). There no data comparing the efficacy these two alternatives.Outcome therapy was retrospectively studied cohorts patients hospitalized due to steroid-refractory moderate UC: 1) a Swedish-Danish cohort (n = 49) treated with single infusion IFX; 2) an Austrian 43) intravenous CsA. After successful therapy, maintenance immunomodulator treatment given 27/33 (82%)...
Secondary thrombocytosis is a clinical feature of unknown significance. In inflammatory bowel disease (IBD), considered marker active disease; however, iron deficiency itself may trigger platelet generation. this study we tested the effect therapy on counts in patients with IBD-associated anemia.Platelet were analyzed before and after from four prospective trials. Further, changes hemoglobin, transferrin saturation, ferritin, C-reactive protein, leukocyte counts, compared. subgroup...