A5027448697- Traditional Chinese Medicine Analysis
- Analytical Chemistry and Chromatography
- Plant-based Medicinal Research
- Microfluidic and Capillary Electrophoresis Applications
- Phytochemistry and Biological Activities
- Pregnancy and preeclampsia studies
- Reproductive System and Pregnancy
- Advanced Chemical Sensor Technologies
- Pharmacological Effects of Natural Compounds
- Metabolomics and Mass Spectrometry Studies
- Chromatography in Natural Products
- Natural product bioactivities and synthesis
- Electrocatalysts for Energy Conversion
- Integrated Energy Systems Optimization
- Advanced Photocatalysis Techniques
- Thermal Analysis in Power Transmission
- Flavonoids in Medical Research
- Phytochemicals and Antioxidant Activities
- Traditional Chinese Medicine Studies
- Health Systems, Economic Evaluations, Quality of Life
- Lung Cancer Research Studies
- Sulfur-Based Synthesis Techniques
- Medicinal Plants and Bioactive Compounds
- Environmental DNA in Biodiversity Studies
- Extraction and Separation Processes
Tianjin University of Traditional Chinese Medicine
2020-2025
University of Hong Kong
2025
Henan University
2025
First Teaching Hospital of Tianjin University of Traditional Chinese Medicine
2024
Tianjin haihe hospital
2022-2023
Peking University
2023
Peking University People's Hospital
2023
China Pharmaceutical University
2020-2022
Wuhan University
2020-2022
Renmin Hospital of Wuhan University
2020-2022
Abstract Introduction Toddalia asiatica (TA) is a classical traditional Chinese medicine used to treat rheumatoid arthritis and contusions. However, research regarding TA quality control currently limited. Objective We aimed establish strategy for identifying markers that can be the evaluation of TA. Method A rapid efficient ultra‐high‐performance liquid chromatography coupled with triple quadrupole tandem mass spectrometry (UHPLC‐MS/MS) method was developed quantitative determination 19...
The use of single-atom catalysts (SACs) with abundant electrocatalytic centers has been identified as the most desirable strategy to inhibit shuttle effect in lithium-sulfur batteries. However, co-contribution from SAC and its support via their interactions for accelerating sulfur reduction reactions (SRR) so far received little attention, since underlying mechanism remains elusive. Herein, guided by density functional theory calculations, Cobalt-SACs supported on a graphitic carbon nitride...
The use of single‐atom catalysts (SACs) with abundant electrocatalytic centers has been identified as the most desirable strategy to inhibit shuttle effect in lithium‐sulfur batteries. However, co‐contribution from SAC and its support via their interactions for accelerating sulfur reduction reactions (SRR) so far received little attention, since underlying mechanism remains elusive. Herein, guided by density functional theory calculations, Cobalt‐SACs supported on a graphitic carbon nitride...
Extracellular vesicles (EVs) are cell-derived, membrane-bound that carry molecular cargo to facilitate communication between cells. During pregnancy, EVs secreted by the syncytiotrophoblast layer of placenta villi, where they mediate functions resident leukocytes and invading extravillous trophoblasts (EVTs) in decidua. This study aims isolate placental (pEVs) from explant examine their regulatory roles on EVT endothelial cell functions. pEVs were successfully isolated ex vivo cultured...
Cardiac hypertrophy is a pivotal pathophysiological step of various cardiovascular diseases, which eventually leads to heart failure and death. Extracts Rhodiola species (Ext.R), class commonly used medicinal herbs in Europe East Asia, can attenuate cardiac both vitro vivo. Serum/glucocorticoid regulated kinase 1 (SGK1) identified as potential target Ext. R. By mass spectrometry-based inhibitory assay, herbacetin (HBT) from Ext.R novel SGK1 inhibitor with IC
Diabetes nephropathy (DN) is one of the main causes death in patients with diabetes. Cystatin C (Cys C) a reliable indicator glomerular filtration function. Therefore, it urgent and meaningful to obtain early warning DN by noninvasive measurement Cys C. In this investigation, novel fluorescence sensor (BSA-AIEgen sensor) was synthesized cross-linking aggregation-induced emission (AIE) characteristics 2-(4-bromophenyl)-3-(4-(4-(diphenylamino) styryl) phenyl) fumaronitrile (TPABDFN) bovine...
Introduction: This study evaluated the cost-effectiveness of atezolizumab + chemotherapy vs. as first-line treatment for extensive-stage small-cell lung cancer (SCLC) in United States (US). Methods: The three health states partitioned survival (PS) model was used over lifetime. Effectiveness and safety data were derived from IMpower133 trial. parametric mixture cure group to explore long-term uncertainty effect immunotherapy, group. Costs pricing files Medicare Medicaid Services, utility...
Pancreatic fibrosis is a pathological characteristic of chronic pancreatitis (CP) and pancreatic cancer. Chaihu Guizhi Ganjiang Decoction (CGGD) traditional Chinese medicine, which widely used in the clinical treatment digestive diseases. However, potential anti-fibrosis mechanism CGGD treating CP remains unclear. Here, we conducted series experiments to examine effect on rat model primary isolated stellate cells (PSCs). The results revealed that attenuated damage, decreased collagen...
Abstract Macrophages are known to be pivotal for ensuring the establishment of immune tolerance microenvironment at maternal–fetal interface. In particular, trophoblasts stay in close contact with decidual macrophages (DMs), which have been reported play an active role modulation polarization DMs. Thus, any dysfunction might associated certain pregnancy‐related complications, such as recurrent spontaneous abortion (RSA). Enhancer zeste homolog 2 (EZH2) is important epigenetic regulatory gene...
Suxiao Jiuxin pill (SX) was a commonly used traditional Chinese medical preparation for treating acute myocardial infarction. However, fewer studies have been reported comprehensively investigating the pharmacokinetic of non-volatile and volatile chemical constituents in SX. For current study, comprehensive sensitive quantitation twenty-one compounds rat plasma developed validated by integrating UPLC-QQQ-MS/MS with GC-MS after oral administration The study performed under acceptable...
For wild natural medicine, unanticipated biodiversity as species or varieties with similar morphological characteristics and sympatric distribution may co-exist in a single batch of medical materials, which affects the efficacy safety clinical medication. DNA barcoding an effective identification tool is limited by its low sample throughput nature. In this study, combining mini-barcode, metabarcoding delimitation method, novel biological sources consistency evaluation strategy was proposed,...