A5059564491- Voice and Speech Disorders
- Salivary Gland Tumors Diagnosis and Treatment
- Dysphagia Assessment and Management
- Head and Neck Cancer Studies
- Gastroesophageal reflux and treatments
- Phonetics and Phonology Research
- Respiratory and Cough-Related Research
- Pleural and Pulmonary Diseases
- Translation Studies and Practices
- Infrared Thermography in Medicine
- Speech Recognition and Synthesis
- Cancer therapeutics and mechanisms
- Pediatric health and respiratory diseases
- Cancer-related molecular mechanisms research
- Music and Audio Processing
- Tracheal and airway disorders
- Pharmacogenetics and Drug Metabolism
- Peroxisome Proliferator-Activated Receptors
- Oral Health Pathology and Treatment
- Tumors and Oncological Cases
- Medical Imaging and Pathology Studies
- Traditional Chinese Medicine Studies
- Cancer Immunotherapy and Biomarkers
- Adipose Tissue and Metabolism
- Drug Transport and Resistance Mechanisms
Beijing Friendship Hospital
2016-2025
Capital Medical University
2016-2025
Capital University
2019
First Affiliated Hospital of Zhengzhou University
2015-2017
Sun Yat-sen University
2013
The assessment of vocal function plays an important role in the diagnosis voice disorders. With continuous development medicine China, evaluation, diagnosis, and treatment disorders are gradually professionalized standardized. Experts Subspecialty Group Voice, Society Otorhinolaryngology Head Neck Surgery, Chinese Medical Association; Laryngopharyngology, Editorial Board Journal Surgery reached expert consensus through clinical research, literature search, quality as well two meetings rounds...
Background: To investigate the value of standard deviation fundamental frequency (F0 SD), jitter, and shimmer for evaluation voice quality description vocal characteristics in patients with disorders. Methods: This prospective cohort study included 4 groups: cord polyps (VCP) group (n=55), early-stage (stage I–II) laryngeal carcinoma (ELC) (n=35), mutational falsetto (MF) (n=17), a normal control (n=29). The participants were asked to emit sustained vowel /a/ raise pitch gradually. Acoustic...
<b><i>Background/Aims:</i></b> Multidrug resistance (MDR) is a critical issue during chemotherapy of cancers. Phorbol 12-myristate 13-acetate (PMA), diester phorbol, typical activator protein kinase C (PKC). In the present study, we investigated effect PMA on MDR and P-glycoprotein (P-gp) gene expression in K562/ADM cells. <b><i>Methods:</i></b> 3-(4,5-dimethylthiazol-2-thiazolyl)-2,5-diphenyltetrazolium bromide assay was used to assess...
Abstract Objective Photodynamic therapy (PDT) is a minimally invasive method with strong tissue selectivity and nonthermal effects. We aim to investigate the efficacy of an in‐office utilizing PDT local application 5‐aminolevulinic acid (ALA) 635 nm diode laser for treating laryngeal leukoplakia. Study Design Retrospective cohort study. Setting Outpatient clinic‐tertiary medical center. Methods This study reviewed 32 patients leukoplakia, including 11 recurrent cases after surgery. All...
Objective Studies showed that photodynamic therapy (PDT) might be able to prevent vocal fold scar formation when treating laryngeal lesions. We aim investigate if PDT improves wound healing and reduces in both prophylactic remodeling procedures performed vivo . Study Design In Methods Vocal stripping was Sprague–Dawley rats. with intraperitoneal injection of 100 mg/kg 5‐Aminolevulinic Acid (5‐ALA) 635 nm laser irradiation 20, 40, 60 J/cm 2 immediately after surgery study the effect 4 weeks...
Objective: To evaluate the value of combined detection negative costimulatory molecule B7-H4 and carcinoembryonic antigen (CEA) in diagnosing malignant benign pleural effusion. Methods: Ninety-seven effusion specimen were collected, 55 which diagnosed as 42 Enzyme-linked immunosorbent assay(ELISA) was used to examine concentration CEA Electro-chemiluminescence immunoassay detect level Receiver operating characteristic (ROC) curve established analyze single or Results: The concentrations...
Background: There were few epidemiological surveys of laryngopharyngeal reflux disease (LPRD) in China. Using the Reflux Symptom Index (RSI) (Chinese version), this study investigated incidence, diagnostic status, risk factors, and common symptoms adult LPRD at otorhinolaryngology-head neck surgery (OHNS) clinics Methods: This was a multicenter cross-sectional with 72 participating medical institutions finally included. The began different ranged from July to October 2017, duration 12...