- Ultrasound Imaging and Elastography
- Gastrointestinal disorders and treatments
- Metastasis and carcinoma case studies
- Gastrointestinal Tumor Research and Treatment
- Photoacoustic and Ultrasonic Imaging
- Gastric Cancer Management and Outcomes
- Ultrasonics and Acoustic Wave Propagation
- Tracheal and airway disorders
- Birth, Development, and Health
- Medical Imaging Techniques and Applications
- Radiomics and Machine Learning in Medical Imaging
- Inflammatory Bowel Disease
- Gastroesophageal reflux and treatments
- Ethics in medical practice
- Dysphagia Assessment and Management
- Colorectal Cancer Surgical Treatments
- Advanced MRI Techniques and Applications
- Diabetes, Cardiovascular Risks, and Lipoproteins
- Ultrasound and Hyperthermia Applications
- Colorectal and Anal Carcinomas
- Inflammatory Biomarkers in Disease Prognosis
- COVID-19 impact on air quality
- Liver Diseases and Immunity
- Bladder and Urothelial Cancer Treatments
- Lung Cancer Diagnosis and Treatment
Huazhong University of Science and Technology
2021-2025
Shenzhen Second People's Hospital
2023-2024
Bristol-Myers Squibb (United States)
2019-2024
Shenzhen University Health Science Center
2023-2024
Soochow University
2023-2024
First Affiliated Hospital of Soochow University
2023-2024
Av Engineering (Czechia)
2023
University of South China
2023
First Affiliated Hospital of Xiamen University
2023
Hainan General Hospital
2022
358 Background: Nivo (antiPD-1) has shown durable responses and manageable safety (ORR, 19.6%; grade 3‒4 treatment-related AEs [TRAEs], 18%) in advBC (Sharma et al. Lancet Oncol 2017), but prolonging survival more pts requires additional approaches to overcome tumor evasion mechanisms. IDO1 allows escape through kynurenine (KYN) production, which stimulates regulatory T cells suppresses effector T-cell proliferation. Anti─PD-1 can upregulate IDO1, supporting the rationale for combining nivo...
Summary Ustilaginoidins, toxic to plants, animals and human, are one of major types mycotoxins produced by Ustilaginoidea virens . In this study, a gene cluster containing the polyketide synthase UvPKS1 was analysed via replacement biochemical studies determine ustilaginoidin biosynthetic pathway in U. first proven be responsible for step biosynthesis, since neither derivatives nor intermediates were when deleted. Replacement ugsO greatly reduced production but increased ratios...
Abstract Background Tricalcium silicate-based sealers have been usually indicated for the single-cone technique and result in more residual filling materials root canal retreatment. Passive ultrasonic irrigation photon-initiated photoacoustic streaming reported to improve removal efficacy of materials. However, abilities both techniques combined with NiTi re-instrumentation remove tricalcium sealer gutta-percha not compared. The aim this study was evaluate laser-activated...
Increasing attention has been attracted to the research of ultrasound computed tomography (USCT). This article reports design considerations and implementation details a novel USCT system named UltraLucid, which aims provide user-friendly platform for researchers develop new algorithms conduct clinical trials. The modular strategy is adopted make highly scalable. A prototype assembled in our laboratory, equipped with 2048-element ring transducer, 1024 transmit (TX) channels, receive (RX) two...
It remains unknown whether transanal endoscopic microsurgery (TEMS) is superior to laparoscopic lower anterior resection (LAR) for the treatment of rectal cancer. This study aimed compare surgical and oncological effectiveness as well safety TEMS LAR in T1-2 cancer patients.T1-2N0 patients were prospectively randomly assigned local excision using (n=30) or radical (n=30). The primary outcome measures postoperative recovery course.The operative duration was significantly shorter than that...
Atherosclerosis is an important cause of cardiovascular disease. The wall shear stress (WSS) one the key factors plaque formation and dislodgement. Currently, WSS estimation based on measurement blood velocity gradient. However, due to lack flow field measurements in carotid stenosis vessels, two distribution forms (parabolic non-parabolic) commonly considered numerical simulations could estimates differ by more than 40%, which seriously affect accuracy mechanical analysis. This study...
(1) Background: Apolipoprotein E(ApoE) plays a critical role in lipid transport. The specific allele of APOE being expressed is associated with the development coronary heart disease (CHD), however mechanisms by which ApoE drives are unclear. In this study, we investigated relationship between allele, lipoprotein metabolome, and CHD severity to provide evidence for efficacy clinical cholesterol-lowering therapy; (2) Methods: Blood samples were collected from 360 patients that actively...
Full-aperture tomography (FAT) is the major image reconstruction method for a circular ring array (CRA)-based ultrasound computed (USCT) system. The FAT technique requires transferring process from temporal domain to spatial domain, during which imaging resolution of USCT degraded by spatial-domain pulse width (SDPW) backprojection areas. To tackle this challenge, study investigates characteristics SDPW and how it degrades resolution. We show that depends on frequency position transmitting...
Background For small gastric subepithelial tumours originating from the muscularis propria, there is no uniform standard for selecting best endoscopic resection method.
Objective: To evaluate the efficacy of laparoscopy combined with transanal endoscopic microsurgery (TEM) in treatment rectal cancer. Methods: A total 60 cancer patients who underwent radical resection from December 2009 to 2013 were enrolled this study. All randomly divided receive either laparoscopic surgery (LA group) or TEM (LT group). Demographics including age and sex, tumor characteristics size, distance anal verge, preoperative staging all recorded. The operation time, hospital stay,...
This paper introduces a health index for measuring the level of societies during lockdown era, i. e., period from March 21, 2020 to April 7, 2020. For this purpose, individual-level survey data Global Behaviors and Perceptions in COVID-19 Pandemic dataset are considered. We focus on cases United States Kingdom, come 11,270 11,459 respondents, respectively. then use unit root tests with structural breaks examine whether COVID-19-related economic shocks significantly affect levels Kingdom. The...
Many studies have been carried out on ultrasound computed tomography (USCT) for its ability to offer quantitative measurements of tissue sound speed. Full waveform inversion (FWI) is a technique reconstructing high-resolution speed images by iteratively minimizing the difference between observed data and synthetic based equation. However, FWI suffers from cycle-skipping, which usually causes convergence at local minimum. Cycle-skipping occurs when phase exceeds half cycle. The simplest way...
There are few studies on presuturing for full-thickness resection. To explore the effect of using clips as a technique endoscopic snare resection with an elastic band (ESR-EB). The clinical data patients who underwent ESR-EB at Shenzhen Second People's Hospital between May 2023 and 2024 were collected. divided into presuture non-presuture groups according to whether tissues stitched before general characteristics, tumor growth position, size, pattern, pathological type, operation time,...
To date, no prospective study has been conducted to compare the safety and effectiveness of endoscopic snare resection with an elastic band (ESR-EB) a transparent cap (ESR-C) for treating gastric muscularis propria lesions. We aimed ESR-EB those ESR-C lesions less than 10 mm in diameter. A total 64 patients were enrolled prospectively from May 2023 November at Shenzhen Hospital Southern Medical University, First Affiliated Shantou People's Zhongshan City. The compared clinical...