A5101885442- Microfluidic and Capillary Electrophoresis Applications
- Analytical Chemistry and Chromatography
- Neonatal Respiratory Health Research
- Respiratory Support and Mechanisms
- Analytical Chemistry and Sensors
- Microfluidic and Bio-sensing Technologies
- Advanced Chemical Sensor Technologies
- Frailty in Older Adults
- Nutrition and Health in Aging
- Innovative Microfluidic and Catalytic Techniques Innovation
- Mass Spectrometry Techniques and Applications
- Electrowetting and Microfluidic Technologies
- Neuroscience of respiration and sleep
- Thermal Regulation in Medicine
- Electrical and Bioimpedance Tomography
- Surface Roughness and Optical Measurements
- Infant Development and Preterm Care
- Long-Term Effects of COVID-19
- Non-Invasive Vital Sign Monitoring
- Apelin-related biomedical research
- Paraoxonase enzyme and polymorphisms
- GDF15 and Related Biomarkers
- CNS Lymphoma Diagnosis and Treatment
- Chemical and Physical Properties of Materials
- Effects of Environmental Stressors on Livestock
Université de Sherbrooke
2020-2024
Laboratoire Eau, Environnement et Systèmes Urbains
2023
Centre Hospitalier Universitaire de Sherbrooke
2021
Génétique Moléculaire Génomique Microbiologie
2016
Université de Rouen Normandie
1995-2009
Abstract The secreted peptide adropin is highly expressed in human brain tissues and correlates with RNA proteomic risk indicators for dementia. Here we report that plasma concentrations predict cognitive decline the Multidomain Alzheimer Preventive Trial (ClinicalTrials.gov Identifier, NCT00672685; mean age 75.8y, SD = 4.5 years, 60.2% female, n 452). Cognitive ability was evaluated using a composite score (CCS) assessed four domains: memory, language, executive function, orientation....
Systemically administered chemotherapy reduces the efficiency of anticancer agent at target tumor tissue and results in distributed drug to non-target organs, inducing negative side effects commonly associated with necessitating repeated administration. Injectable hydrogels present themselves as a potential platform for non-invasive local delivery vehicles that can serve slow-releasing depot fills vasculature, tissue, or resection cavities. Herein, we have systematically formulated tested an...
Primary central nervous system lymphomas (PCNSL) are rare and aggressive CNS tumors. Current management involves high-dose methotrexate (HD-MTX) typically administered intravenously (IV), despite the existence of blood-brain barrier (BBB), which significantly decreases its bioavailability. Cerebral intra-arterial chemotherapy (CIAC) coupled with osmotic BBB disruption (OBBBD) can theoretically circumvent this issue.We performed a retrospective analysis patients newly diagnosed PCNSL treated...
Affinity capillary electrophoresis (ACE) is a robust tool for the study of noncovalent biomolecular interactions and to determine binding constants. It advantageous due speed analysis, high reproducible separation efficiencies, low consumption analytes, ability several at same time, cover wide range affinity. The use an ion trap-mass spectrometer as sensitive specific detector, coupled on-line with classical UV permits extracting simultaneously electropherograms corresponding each ionic...
Abstract Physical activity (PA) has been shown to moderate the negative effects of obesity on pro-inflammatory cytokines but its relationship with adipokine progranulin (PGRN) remains poorly investigated. This study aimed examine cross-sectional main and interactive associations body mass index (BMI) PA level circulating PGRN in older adults. Five-hundred twelve participants aged 70 years involved Multidomain Alzheimer Preventive Trial (MAPT) who underwent plasma measurements (ng/mL) were...
Animal experiments suggest that total liquid ventilation (TLV) induces less ventilator-induced lung injury (VILI) than conventional mechanical gas ventilation. However, TLV parameters optimally minimize VILI in newborns remain unknown. Our objective was to compare inflammation between low (L-VT) and high (H-VT) tidal volume evaluate impacts on the weaning process. Sixteen anesthetized paralyzed newborn lambs were randomized an L-VT group (initial of 10 mL/kg at 10/min) H-VT 20 5/min). Five...
Abstract Background Weight and appetite regulation have been associated with the expression secretion of ATPase inhibitory factor 1 (IF1) growth differentiation factor-15 (GDF-15), 2 potential biomarkers for age-related mitochondrial dysfunction. The aim was to explore associations between these nutritional variables in Multidomain Alzheimer Preventive Trial study. Methods IF1 GDF-15 plasma levels were quantified at 1-year follow-up. status measured using Mini Nutritional Assessment (MNA)...
Until now, fluorescein sodium salt has been used to generate the background signal for indirect fluorimetric detection of inorganic cations or mono-charged organic anions separated by Capillary Zone Electrophoresis (CZE).In this paper, we extend use simultaneous CZE analysis (Cl -, NO - 2 , 3 SO 2- 4 F -) and polycharged (oxalate citrate).The electroosmotic flow was reversed using tetradecyltrimethylammonium bromide (TTAB) hexadimethrine.The specific problems linked utilization a positively...
Glow Discharge - Optical Emission Spectroscopy (GD-OES) complements other surface/depth profile analysis techniques as Auger, SIMS, XPS for the characterization of thin and thick film/layers. Thanks to Pulsed Rf Source, any material, conductive non conductive, can be analyzed. Single or multiple layers from nm several 100 microns thickness sputtered in minutes on type substrates (rigid, flexible, glass, steel, Si...). Dynamic terms concentration is ppm 100%. O, N, H, Cl, F Li easily analyzed...