- Neonatal Respiratory Health Research
- Congenital Diaphragmatic Hernia Studies
- COVID-19 Impact on Reproduction
- Crystallization and Solubility Studies
- X-ray Diffraction in Crystallography
- Ultrasound in Clinical Applications
- Fermentation and Sensory Analysis
- Neonatal Health and Biochemistry
- Maternal Mental Health During Pregnancy and Postpartum
- Horticultural and Viticultural Research
- Congenital Heart Disease Studies
- Phytochemicals and Antioxidant Activities
- Tea Polyphenols and Effects
- Methemoglobinemia and Tumor Lysis Syndrome
- Hyperglycemia and glycemic control in critically ill and hospitalized patients
- Mechanical Circulatory Support Devices
- Cardiovascular Conditions and Treatments
- Metabolomics and Mass Spectrometry Studies
- Advanced Proteomics Techniques and Applications
- Hemoglobinopathies and Related Disorders
- Diet, Metabolism, and Disease
- Nutritional Studies and Diet
- Bone fractures and treatments
- Clinical Nutrition and Gastroenterology
- Infant Nutrition and Health
University of Bari Aldo Moro
2024
Agostino Gemelli University Polyclinic
2010-2024
Sapienza University of Rome
2023
University of Perugia
2023
Università Cattolica del Sacro Cuore
2012-2023
Istituti di Ricovero e Cura a Carattere Scientifico
2022
Ospedale Monaldi
2009-2015
Fondazione Roma
2014
RELX Group (Netherlands)
2014
Catholic University of America
2008-2012
The long-term outcomes of newborns exposed to SARS-CoV-2 infection in utero or during the first hours life are still unknown. We performed a single-center, prospective, observational study born from mothers with microbiologically confirmed pregnancy at time delivery. Infants were offered multidisciplinary follow-up consisting nasopharyngeal Polymerase Chain Reaction test birth and 48–72 h life, auxological growth neurological development, serologic testing, audiological ophthalmological...
Abstract Background Diaphragm dysfunction is associated with poor outcomes in critically ill patients. Ventilator‐induced diaphragmatic (VIDD), including diaphragm atrophy (DA), poorly studied newborns. We aimed to assess VIDD and its associations Methods Single‐center prospective study. thickness was measured at end‐inspiration (TDI) end‐expiration (TDE) on the right midaxillary line. DA defined as decrease TDE ≥ 10%. Daily measurements were recorded preterm newborns invasive mechanical...
The Cardiac Network for Heart Failure integrates patients into a dedicated clinical pathway to enhance care and improve quality of life, creating personalized approach according current guidelines. This study seeks evaluate nurses’ familiarity with health literacy tools assessment scales in managing chronic heart failure patient outcomes reduce hospital readmissions through survey on scales. Our findings underscore the need continuous education regular training tools. Enhanced structured is...
Abstract Objective To assess changes in neonatal lung ultrasonography score (nLUS) after surfactant administration preterm infants with respiratory distress syndrome (RDS). Working Hypothesis The reduction of nLUS before (nLUSpre), 2 hours (nLUS2h), and 12 (nLUS12h) to identify patients who will not need a second treatment. Study Design Setting Prospective observational study the tertiary intensive care unit. Patients Selection Forty‐six neonates RDS 32 weeks median gestational age (IQR...
Abstract Objective To propose an early lung ultrasound (LUS) score for the prediction of need respiratory assistance in newborns gestational age (GA) ≥ 33 weeks presenting distress. Study Design and Setting Multicenter, prospective observational study third‐level neonatal intensive care units. Patient Selection Infants with GA + 0 distress within 3 h life. Methods Three LUS each patient were collected: life (T0), at 4–6 (T1), resolution symptoms (T2). The primary aim was to assess validity...
<h3>Objective</h3> To evaluate the risk of upper gastrointestinal complications (UGIC) associated with drug use in paediatric population. <h3>Methods</h3> This study is part a large Italian prospective multicentre study. The population included children hospitalised for acute conditions through emergency departments eight clinical centres. Patients admitted UGIC (defined as endoscopically confirmed gastroduodenal lesions or clinically defined haematemesis melena) comprised case series;...
Continuous glucose monitoring using subcutaneous sensors is useful in the management of control neonatal intensive care. We evaluated feasibility and reliability a continuous system population very low birth weight neonates needing parenteral nutrition. Moreover, we presented percentiles glycemia studied population.Very were enrolled within 24 h from birth. An ENLITE sensor connected to was inserted maintained for at least 72 h. Data obtained with glucometer compared. Calibration performed...
Smoking accelerates atherosclerosis and is a well-known risk factor for acute cardiovascular complications; however, the mechanisms of these effects have not been completely clarified. Recently developed proteomic approaches may offer new clues when combined with well-established functional tests. Platelet proteome healthy smokers non-smokers was resolved by two-dimensional difference gel electrophoresis, compared Decyder software identified mass spectrometry analysis (nano-LC-MS/MS). In...
Abstract Background Early discharge of healthy late preterm and full term newborn infants has become common practice because the current social economic necessities. Severe jaundice, even kernicterus, developed in some discharged early. This study was designed to elaborate a percentile-based hour specific total serum bilirubin (TSB) nomogram assess its ability predict absence risk for subsequent non physiologic severe hyperbilirubinaemia before discharge. Methods A hour-specific TSB values...
Abstract Blood orange juice has a high content in anthocyanins, especially represented by delphinidin‐3‐glucoside (D3G), cyanidin‐3‐glucoside (C3G) and cyanidin‐3‐(6‐malonylglucoside) (CMG). An LC‐MS/MS method for the simultaneous determination of D3G C3G human plasma urine was developed validated. After sample preparation SPE, chromatographic separation performed with an RP‐C 18 column, using water/methanol linear gradient. The quantitation target compounds determined multiple reaction...
Transcutaneous bilirubinometry is widely used to predict hyperbilirubinemia by using several devices. The aim of this study was compare the predictive ability BiliCheck vs JM-103 in identifying neonates not at risk significant hyperbilirubinemia, putting data obtained with two instruments on our transcutaneous bilirubin nomogram built BiliCheck.Transcutaneous (TcB) measurement performed when jaundice appeared newborn babies and/or just before discharge from hospital. It forehead within 5...
The aim of this study was to characterize the ampelographic and genetic profiles Vitis vinifera L. cv. Nero Antico di Pretalucente describe grape-borne fungal communities. oenological characteristics aroma profile wine obtained by spontaneous fermentation were also investigated. Microsatellite traits indicated that cultivar presented a unique profile, therefore it can be considered in its own right autochthonous Gessopalena village. Next-generation sequencing analysis revealed Aureobasidium...
To describe how SARS-CoV-2 infection at the time of delivery affected maternal and neonatal outcomes across four major waves COVID-19 pandemic in Italy.
Objective To evaluate the efficacy of a strict glycaemic control protocol using continuous glucose monitoring (CGM) in infants at high risk dysglycaemia with aim reducing number dysglycaemic episodes. Design Randomised controlled trial. Setting Neonatal intensive care unit, Fondazione Policlinico Universitario Agostino Gemelli, IRCCS, Rome. Patients All <1500 g fed on parental nutrition (PN) since birth were eligible. A total 63 eligible and 48 randomised. Intervention participants wore...