- Spine and Intervertebral Disc Pathology
- COVID-19 and healthcare impacts
- Gastric Cancer Management and Outcomes
- Parathyroid Disorders and Treatments
- Infectious Diseases and Tuberculosis
- Esophageal Cancer Research and Treatment
- Trauma and Emergency Care Studies
- Intracerebral and Subarachnoid Hemorrhage Research
- Case Reports on Hematomas
- Pituitary Gland Disorders and Treatments
- COVID-19 Clinical Research Studies
- Medical Imaging and Pathology Studies
- Cancer Treatment and Pharmacology
- Neuroendocrine Tumor Research Advances
- Diabetes and associated disorders
- Genetic Syndromes and Imprinting
- S100 Proteins and Annexins
- Adrenal and Paraganglionic Tumors
- Pancreatitis Pathology and Treatment
- Advanced Breast Cancer Therapies
- Esophageal and GI Pathology
- Spinal Hematomas and Complications
- Management of metastatic bone disease
- Medical Practices and Rehabilitation
- Orthopedic Infections and Treatments
Yale University
2021-2023
Vrije Universiteit Amsterdam
2022
Amsterdam University Medical Centers
2022
University of Toledo Medical Center
2015-2017
Creative Commons
2017
University of Toledo
2017
Janssen (Germany)
2016
Massachusetts General Hospital
2013
Addenbrooke's Hospital
1966
Objective Although there is growing awareness of the long‐term cognitive effects repetitive mild traumatic brain injury (rmTBI; eg, sports concussions), whether repeated concussions cause deficits remains controversial. Moreover, depend on increased amyloid β deposition and tau phosphorylation or are worsened by apolipoprotein E4 allele unknown. Here, we use an experimental model rmTBI to address these clinical controversies. Methods A weight drop was used that results in without loss...
Objective To report and evaluate the outcomes of patients undergoing definitive treatment for distal femur nonunion after initial with a locking plate. Methods Fourteen who had undergone at an academic Level 1 trauma center from May 2007 to December 2013 were identified fracture database. Thirteen them female; average age was 65 years (range, 50–84 years). Ten sustained their injuries in falls ground level, four motor vehicle accidents. Twelve obese (body mass index ≥30), 10 diabetes, none...
Multiglandular and familial parathyroid disease constitute important fractions of primary hyperparathyroidism (PHPT). Germline missense variants GCM2, a regulator development, were observed in isolated sporadic PHPT. However, as these previously reported GCM2 occur at relatively high frequencies the population, understanding their potential clinical utility will require both additional penetrance data functional evidence relevant to tumorigenicity.Determine frequency interest among patients...
DESPITE the increasing frequency with which primary hyperparathyroidism has been reoog- nized in recent years (Dent, 1962), reports of its faamilial occurrence are few: search literature !revealsonly 13 examples.This paper records another affected family and draws attention to need for more systematic study relatives patients wi-th this disorder. The FamilyThe pedigree is shown Fig. 1.Tihe members, II 1, 3 5, were all female suffered from chief cell hyper- plasia parathyroids.Brief clinical...
Background: For patients with operable locally advanced esophageal carcinoma (LA-EC), we hypothesized that pre-operative induction chemotherapy followed by chemoradiotherapy (IC-CRT) would improve progression-free survival (PFS) and overall (OS) when compared to (CRT). Methods: This was a single institution retrospective cohort study including LA-EC who received preoperative-intent IC-CRT vs. CRT between 2013–2019. The Kaplan-Meier method used estimate OS PFS. Cox proportional hazards...
Journal of Cancer Metastasis and Treatment is an open access journal, focusing on basic clinical studies related to cancer cell, cell biology, oncology, radiation therapy radiology, obstetrics gynecology, pediatrics, surgery, hematology, neuro-oncology, etc.
A 64-year-old-female presented with progressive left foot weakness, low back and radicular pain after a sided S1 transforaminal epidural steroid injection (ESI). Magnetic resonance imaging revealed side L5-S1 large extradural heterogeneous mass layering areas suggesting different stages of hematoma formation. Past medical history was significant for peripheral vascular disease transient ischemic attacks, which she took aspirin clopidogrel (antiplatelet agent). These medications were...
Abscess of the iliopsoas muscle is a rare condition that requires high degree clinical suspicion for diagnosis. High mortality rates highlight need prompt recognition. We report case 26-year-old man, with history intravenous drug use, who was referred from an outside facility sacral fracture and gluteal abscess. Sacral trauma occurred 3 weeks before presentation, progressive worsening buttock pain. The patient treated irrigation débridement Follow-up MRI revealed communicating abscess...
BackgroundThe COVID-19 pandemic necessitated adjustments to nearly all aspects of healthcare, including surgical care. The effects these have not been well studied on acute problems conventionally managed non-electively in large, tertiary care centers.Methods.A retrospective analysis admitted patients with cholecystitis at a US academic center was performed. We compared the presentation, management, and 30-day outcomes during 2-month time period early COVID, pre-COVID control group over...
Following presentation of the CALGB 80803 trial, which demonstrated notably high pathologic complete response (pCR) rates with induction FOLFOX followed by chemoradiotherapy (CRT), our institution more routinely incorporated chemotherapy (IC) into management LA-EC patients. However, improvements in progression-free (PFS) or overall survival (OS) this regimen compared to pre-operative CRT alone have not yet been shown. We hypothesized IC-CRT would lead an improvement OS and PFS when...