A5084788318- Salmonella and Campylobacter epidemiology
- Adipose Tissue and Metabolism
- Dental Implant Techniques and Outcomes
- Listeria monocytogenes in Food Safety
- Oral microbiology and periodontitis research
- Species Distribution and Climate Change
- Plant Virus Research Studies
- Orthopaedic implants and arthroplasty
- Ecology and Vegetation Dynamics Studies
- Immunodeficiency and Autoimmune Disorders
- Food Safety and Hygiene
- Bone Tissue Engineering Materials
- Plant and animal studies
- Pesticide Residue Analysis and Safety
- Plant and Fungal Interactions Research
- Viral gastroenteritis research and epidemiology
- Nitric Oxide and Endothelin Effects
- Adipokines, Inflammation, and Metabolic Diseases
- Bone health and osteoporosis research
- Antibiotics Pharmacokinetics and Efficacy
- Oral health in cancer treatment
- Connective tissue disorders research
- Telomeres, Telomerase, and Senescence
- Traditional Chinese Medicine Studies
- Phytoplasmas and Hemiptera pathogens
The University of Tokyo
2019-2023
Tokyo Medical and Dental University
2012-2017
Showa University
2013-2016
RIKEN BioResource Research Center
2012
Tokyo Metropolitan University
2011
Tokyo Metropolitan Institute of Gerontology
2011
Asahikawa Medical College Hospital
2009
Mie University
2003
Chiba Rosai Hospital
1984
To investigate the direct relationship of oxidative stress with obesity and insulin resistance in men, we measured plasma levels 8-epi-prostaglandin F2alpha (PGF2alpha) 14 obese 17 nonobese men evaluated their body mass index; fat weight; visceral, sc, total areas, by computed tomography; glucose infusion rate during a euglycemic hyperinsulinemic clamp study. Obese had significantly higher concentrations 8-epi-PGF2alpha than (P < 0.05). The were correlated index (r = 0.408; P 0.05), weight...
The purpose of this study was to investigate the association between visceral adiposity or triglyceride (TG) metabolism and insulin resistance in metabolically obese, normal weight (MONW) Japanese individuals with glucose tolerance.We evaluated body fat areas, lipid profiles, infusion rate (GIR) during a euglycemic-hyperinsulinemic clamp 20 MONW subjects (BMI <25 kg/m(2)and areas 100 cm(2)) tolerance. Body were measured by computed tomography scans. Control data obtained from kg/m(2) <100...
The microbial differences between peri-implantitis and periodontitis in the same subjects were examined using 16S rRNA gene clone library analysis real-time polymerase chain reaction.Subgingival plaque samples taken from deepest pockets of sites six subjects. prevalence bacteria was analysed a reaction.A total 333 different taxa identified 799 sequenced clones; 231 (69%) uncultivated phylotypes, which 75 novel. numbers bacterial at 192 148 respectively. composition more diverse when compared...
Abstract Polymicrobial diseases, which can be life threatening, are caused by the presence and interactions of multiple microbes. Peri-implantitis periodontitis representative polymicrobial diseases that show similar clinical symptoms. To establish a means differentiating between them, we compared microbial species functional genes in situ performing metatranscriptomic analyses peri-implantitis samples obtained from same subjects (n = 12 each). Although two differed terms 16S rRNA-based...
OBJECTIVE: It is well known that nitric oxide synthase (NOS) expressed and it modulates glucose transport in skeletal muscles. Recent studies have shown adipose tIssues also express inducible endothelial (eNOS). In the present study, we investigated whether (NO) induces uptake adipocytes, signaling pathway involved NO-stimulated 3T3-L1 adipocytes. METHODS: First, determined expression of eNOS then these cells were treated with NO donor sodium nitroprusside (SNP) and/or insulin,...
Consumption of raw or undercooked poultry products contaminated with Campylobacter has been identified as a risk factor for human campylobacteriosis. We determined whether slaughtering Campylobacter-positive flocks was associated contamination chicken derived from Campylobacter-negative slaughtered at the same abattoir. The presence investigated in 22 broiler farms 1 week prior to slaughter and one abattoir on nine separate days. A total 600 bulk packed were tested, 198 (33.0%) found be...
An experimental model with accelerated but not drastic renal senescence seemed useful to recognize the mechanisms of how kidney function deteriorates age. Senescence marker protein-30 (SMP30), whose expression decreased age and was sex-independent, is mainly expressed in hepatocytes proximal tubular cells. Therefore, we established a SMP30 deficient strain mice C57BL/6 background by gene targeting investigate whether this molecule involved cell senescence. Male knockout (SMP30Y/-) male...
A novel mechanism of highly mineralized bone durability almost independent viscoelastic behaviour along with a series nanoindentation experiments is reported.
SUMMARY Human salmonellosis cases, particularly those caused by Salmonella Enteritidis, have been closely linked to egg consumption. This epidemiological survey was conducted determine the baseline prevalence and identify risk factors for in laying-hen farms Japan. Caecal excrement samples dust were obtained from 400 flocks 338 farms. identified 20·7% of 19·5% flocks. The significantly higher reared windowless houses than open houses. In addition, presence when house implemented induced...
Abstract Plum pox virus (PPV) is one of the most important plant viruses causing serious economic losses. Thus far, strain typing based on definition 10 monophyletic strains with partially differentiable biological properties has been sole approach used for epidemiological characterization PPV. However, elucidating genetic determinants underlying intra‐strain variation among populations or isolates remains a relevant but unexamined aspect epidemiology virus. In this study, complete...
We report the complete genome sequence of a Japanese isolate Tea plant necrotic ring blotch virus (TPNRBV-J). The predicted TPNRBV-J genes have same organization as those Chinese isolate, and 5' termini segments conserved nucleotide sequences.
With the aim of comparing prevalence Shiga toxin-producing Escherichia coli (STEC) O157 and O26 between beef dairy cattle, we collected rectal content samples from 250 cattle on 25 farms cows July through September 2011. STEC was isolated 16 7 farms, while no any farms. This result suggests that is higher in than cattle. 1 animal each herds, therefore, it not possible to compare statistically
To investigate the prevalence and characterization of foodborne pathogens [Campylobacter spp., Shiga toxin-producing Escherichia coli (STEC), Listeria monocytogenes Salmonella spp.] in dairy cows, rectal content grab samples were collected from 250 cows reared on 25 farms eastern Japan December 2010 through February 2011. Campylobacter jejuni was isolated 106 (42%) 23 (92%) farms, STEC O157 three one farm, L. another enterica subsp. serovar Typhimurium eight farm. O26 not any investigated....
The naturally occurring T lymphocytotoxic antibodies in patients with viral and related skin diseases were investigated compared those of systemic lupus erythematosus (SLE). incidences exanthema suspected infection, infectious mononucleosis, rubella pityriasis rosea 28%, 44%, 8% 28% respectively. Sera from herpes zoster erythema infectiosum did not show positivity. Incidence SLE sera as positive control was 82%. detected similar nature to patients, but transient lower titer than SLE.
Residue analysis of clenbuterol (CBL) in bovine and horse tissues cow's milk using enzyme-linked immunosorbent assay (ELISA) with alkaline phosphatase as the label is described. The detection limit ELISA established here was 0.1ng/g (0.1ppb). Tissue samples were homogenized 3% metaphosphoric acid cleaned up by liquid-liquid extraction ethyl acetate. After evaporation acetate extract, CBL residue measured ELISA. Recoveries 75-96% for tissues, 74-98% 99% milk. not detectable after 6th day...
Objectives: Simulation education close to actual practice is desirable learn clinical skills and risk management.The usefulness of a patient robot for orthodontic bonding was investigated in this study from June 2013 August 2013. Methods: Nine subjects participated training using mannequin the robot, lecture, mutual training.The following items were analyzed: A. examiner's score, B. time, C. bracket mounting position, D. questionnaire results. Results:When performed twice on same day, score...
Abstract We provide a 22‐year period (1994–2015) dataset of flowering records herbaceous plant species in Tokyo, Japan. Trained volunteers the citizen group conducted field surveys using science approach. During monthly surveys, recorded phenology plants an area Institute for Sustainable Agro‐ecosystem Services and Tanashi Forest (The University Tokyo) Nishitokyo City, In all, 5982 observations on 401 including 11 subspecies, 44 varieties, six forma from 70 families were collected Tokyo....