A5085912495- Neuroblastoma Research and Treatments
- Cancer, Hypoxia, and Metabolism
- Neurofibromatosis and Schwannoma Cases
- Adrenal and Paraganglionic Tumors
- Glioma Diagnosis and Treatment
- Childhood Cancer Survivors' Quality of Life
- Lymphoma Diagnosis and Treatment
- Cancer therapeutics and mechanisms
- Remote Sensing and Land Use
- Remote-Sensing Image Classification
- Acute Lymphoblastic Leukemia research
- Remote Sensing in Agriculture
- Lung Cancer Research Studies
- CNS Lymphoma Diagnosis and Treatment
- EEG and Brain-Computer Interfaces
- Insect Utilization and Effects
- Breast Cancer Treatment Studies
- Cancer Cells and Metastasis
- Polyomavirus and related diseases
- Global Cancer Incidence and Screening
- Pancreatic and Hepatic Oncology Research
- Viral-associated cancers and disorders
- Medical Imaging Techniques and Applications
- Sarcoma Diagnosis and Treatment
- Cytomegalovirus and herpesvirus research
Children Cancer Hospital
2015-2024
Arab Academy for Science, Technology, and Maritime Transport
2024
Budapest University of Technology and Economics
2023-2024
Cairo University
2014-2023
South Valley University
2020-2023
Beni-Suef University
2023
Pediatric Oncology Group
2016-2022
Zewail City of Science and Technology
2021
Meta (Israel)
2018
Royal Liverpool and Broadgreen University Hospital NHS Trust
2017-2018
Machine learning sits at the core of many essential products and services Facebook. This paper describes hardware software infrastructure that supports machine global scale. Facebook's workloads are extremely diverse: require different types models in practice. diversity has implications all layers system stack. In addition, a sizable fraction data stored Facebook flows through pipelines, presenting significant challenges delivering to high-performance distributed training flows....
Multi-Layer Perceptron (MLP) is one of the Feed-Forward Neural Networks (FFNNs) types. Searching for weights and biases in MLP important to achieve minimum training error. In this paper, Moth-Flame Optimizer (MFO) used train (MLP). MFO-MLP search error high classification rate. Five standard datasets are utilized evaluate performance proposed method. Moreover, three function-approximation test The method (i.e. MFO-MLP) compared with four well-known optimization algorithms, namely, Genetic...
Malignant spinal cord compression (MSCC) is a common complication of cancer. Paraspinal neuroblastoma (NB) in the thoracic, abdominal and pelvic regions may extend into neural foramina causing nerve roots even cord. The prompt initiation specific treatment can improve neurological outcome. aim present study was to review clinical features, management received factors that affect outcome patients with MSCC caused by paraspinal NB. During period between July 2007 December 2012, total 576 NB...
IntroductionThe introduction of biological and synthetic meshes has revolutionised the practice implant-based breast reconstruction (IBBR) but evidence for effectiveness is lacking. The iBRA (implant Breast Reconstruction evAluation) study a national trainee-led project that aims to explore outcomes IBBR inform design future trial. We report results National Practice Questionnaire (NPQ) which aimed comprehensively describe provision across UK.MethodsA questionnaire investigating local...
IntroductionThe 2008 National Mastectomy and Breast Reconstruction Audit demonstrated marked variation in the practice outcomes of breast reconstruction UK. To standardise improve for patients, British professional associations developed best-practice guidelines with specific guidance newer mesh-assisted implant-based techniques. We explored degree uptake within units performing (IBBR) as first phase implant Evaluation (iBRA) study.MethodsA questionnaire by iBRA Steering Group was completed...
Abstract Childhood cancer is a priority in Egypt due to large numbers of children with cancer, suboptimal care and insufficient resources. It difficult evaluate progress survival because paucity data National Cancer Registry. In this study, we studied rates trends the largest available cohort (n = 15 779, aged 0‐18 years) from between 2007 2017, treated at Children's Hospital Egypt‐(CCHE), representing 40% 50% all childhood cancers across Egypt. We estimated 5‐year overall (OS) for 14 808...
Activation of herpes virus 6 (HHV6) has seen in Hodgkin's and non-Hodgkin's Lymphoma (HL&NHL) as a result lymphoma associated immunosuppression. Multiple studies have suggested an association between both HHV6 cytomegalovirus CMV for development disease affecting the pathogenesis lymphoma. Therefore, this study investigated frequency HHV6, its impact on clinical manifestations possible with risk infection pediatric patients. Presence DNA was by PCR assay WBC's plasma samples from 50 patients...
Epstein-Barr virus (EBV) and human cytomegalovirus (CMV) infections are environmental risk factors affecting the outcome of cancer due to an impairment in cell-mediated immunity. Therefore, this study aimed detect frequency EBV CMV DNA their association with clinical characteristics pediatric leukemic patients. Samples 50 immunocompromised patients 30 apparently healthy children were subjected amplification by one version PCR targeting Bam H1 W region genomic EBV, UL97 a second round PCR....
Abstract Background Tumor boards are part of standard care patients with complex cancers, but appropriate multidisciplinary expertise and infrastructure often not available in low‐ middle‐income countries (LMIC) for pediatric such as neuroblastoma. Our goal was to review results a Global Neuroblastoma Network (GNN) tumor board accessible LMIC. Methods De‐identified clinical cases presented via internet conference during weekly GNN virtual from 2010 through 2020 were evaluated standardized...
Ependymomas are the third most common pediatric central nervous system (CNS) tumors, accounting for 6-12% of brain tumors in children. Management these remains challenging and recurrence occurs over 50% cases, mainly when complete resection is not achieved before radiotherapy. The 5-year overall survival (OS) ranges from 39 to 64%, with a progression-free (PFS) rate 23-45%. study aimed describe OS PFS rates cases ependymoma. It also evaluate effects different variables on disease outcomes....
In Egypt, El-Mansourah Conurbation (EMC) is the second largest urban complex after Cairo Conurbation. This study focuses on identifying seasonal trends in land surface temperature during daytime/nighttime both and rural areas (RA), as well corresponding heat island (UHI) intensity 2001 to 2021. A time series of Moderate Resolution Imaging Spectroradiometer (Terra MODIS) images was analyzed using statistical methods Mann-Kendall test (MKT) Theil-Sen estimator (TSE). The findings showed that...
Background: Neuroblastoma (NB) is remarkable for its wide spectrum of clinical behavior and biological characteristics in relation to outcome. The use aggressive therapy, including autologous hematopoietic stem cell transplantation (HSCT) the addition isoretionin (cis-Retinoic Acid/cis-RA), has increased survival rates patients with advanced disease. Methods: Pediatric 271 newly diagnosed high risk NB were prospectively enrolled into study. Patients received neoadjuvant chemotherapy...
The study aims to evaluate survival outcome in newly diagnosed pediatric intermediate risk neuroblastoma patients treated at the Children Cancer Hospital – Egypt and their relation various clinical pathological factors. included stage 3 <1.5 years, children 1.5 years or older with disease favorable histopathological features, infants (<1 year) International Neuroblastoma Staging System (INSS) 4 disease, 1–1.5 biology, s (with unfavorable biologic features). Patients received systemic...
According to the Fifth National Wilms Tumor Study (NWTS-5), tumor-specific loss of heterozygosity (LOH) for chromosomes 1p and 16q identifies a subset patients with tumor (WT) who despite having favorable histology (FH) have significantly increased risk relapse death. We aimed find out LOH frequencies in FH-WT as well its correlation survival outcome epidemiologic clinical characteristics. Data presenting Cancer Institute, Egypt, were retrospectively analyzed. Paraffin blocks tested using...
Neuroblastoma (NBL) in infants has the potential to regress/mature spontaneously. The literature showed some cases, subjected initial observation, with reasonable outcome. Deferring/avoiding active treatment was investigated selected favorable NBL cases. Patients enrolled on watch and see strategy (W&S) had small primary tumor, localized stages 1 2, uncomplicated stage 4s, or 3. Tissue biopsy not mandatory for below 6 months mass. On progression, intervention indicated according disease risk...
Unplanned seizures are caused by a disorder in the central nervous system known as epilepsy. Although significant advancements have been made realm of non-EEG wearable devices, there is still much room for improvement field EEG-based seizure detection and prediction using ML. The management epilepsy has lot promise to be aided non-invasive technology. suggested study intends design implement support vector machine (SVM) classification-based epileptic based on various devices. proposed...
Lymphoblastic lymphoma (LL) comprises approximately 20% of childhood non-Hodgkin (NHL); however, few studies had investigated the role 18F-FDG-PET/CT in pediatric LL patients. We aim this study to assess initial staging newly diagnosed patients with as well assessment response after induction chemotherapy.A prospective enrolled biopsy proven presenting Children Cancer Hospital Egypt (CCHE) during period from October 2014 2016. was done initially before therapy and chemotherapy all The were...