A5103240167- Glaucoma and retinal disorders
- Retinal Diseases and Treatments
- Software Testing and Debugging Techniques
- Corneal surgery and disorders
- Software Engineering Research
- Software Reliability and Analysis Research
- Vitamin C and Antioxidants Research
- Vitamin D Research Studies
- VLSI and Analog Circuit Testing
- Retinal Imaging and Analysis
- Vitamin K Research Studies
- Effects and risks of endocrine disrupting chemicals
- Cerebral Venous Sinus Thrombosis
- Heavy Metal Exposure and Toxicity
- Potassium and Related Disorders
- Photonic and Optical Devices
- Electroconvulsive Therapy Studies
- Organizational Downsizing and Restructuring
- Ocular Infections and Treatments
- Radiation Effects in Electronics
- Advancements in Photolithography Techniques
- Teaching and Learning Programming
- Acne and Rosacea Treatments and Effects
- Alcoholism and Thiamine Deficiency
- Death Anxiety and Social Exclusion
University College London
2013-2024
Moorfields Eye Hospital
2016-2024
Moorfields Eye Hospital NHS Foundation Trust
2013-2024
Omron (Japan)
2024
Novartis (Ireland)
2024
City, University of London
2024
Azienda Ospedaliero Universitaria Maggiore della Carita
2024
Università degli Studi del Piemonte Orientale “Amedeo Avogadro”
2024
Santen (Japan)
2024
Roche (Switzerland)
2024
Treatments for open-angle glaucoma aim to prevent vision loss through lowering of intraocular pressure, but our knowledge no placebo-controlled trials have assessed visual function preservation, and the observation periods previous (unmasked) typically been at least 5 years. We preservation in patients given latanoprost compared with those placebo.In this randomised, triple-masked, trial, we enrolled newly diagnosed ten UK centres (tertiary referral centres, teaching hospitals, district...
Background: Both coplanar and noncoplanar polychlorinated biphenyls (PCBs) exhibit neurotoxic effects in animal studies, but individual congeners do not always produce the same as PCB mixtures. Humans genetically have > 60-fold differences hepatic cytochrome P450 1A2 (CYP1A2)-uninduced basal levels 12-fold variability aryl hydrocarbon receptor (AHR)affinity; because CYP1A2 is known to sequester PCBs AHR ligands include PCBs, both genotypes can affect response.Objectives: We aimed develop a...
A senior colleague has conducted a study and asks me to analyse their data. They give an excel spreadsheet containing 80 observations of intraocular pressure (IOP)—40 which were made after using drug 40 B (see table 1). View this table: Table 1 80 IOP My find out whether or is better in terms reducing IOP. I think back my medical school training recall something called t test, believe may be relevant. Using the internet discover that there indeed test can used compare means two groups....
Organisms using oxygen for aerobic respiration require antioxidants to balance the production of reactive species during metabolic processes. Various – including humans and other primates suffer mutations in GULO gene encoding L ‐gulono‐ γ ‐lactone oxidase; is rate‐limiting enzyme biosynthesis ascorbate, an important cellular antioxidant. Animals lacking ability synthesize vitamin C develop scurvy without dietary supplementation. The Gulo( − / ) knockout (KO) mouse requires oral supplemental...
The terms “Oracle Problem” and “Non-testable system” interchangeably refer to programs in which the application of test oracles is infeasible. Test are an integral part conventional testing techniques; thus, such techniques inoperable these programs. prevalence oracle problem has inspired research community develop several automated that can detect functional software faults These include N-Version testing, Metamorphic Testing, Assertions, Machine Learning Oracles, Statistical Hypothesis...
Purpose: Chemical burns due to alkalis cause extensive damage the ocular surface leading blindness. Assessment of burn could be challenging severe opacity, inflammation, and angiogenesis. Anterior segment optical coherence tomography (AS-OCT) OCT angiography (OCTA) may provide fast, non-invasive deep tissue visualization pathology with high sensitivity in conjunction slit-lamp analysis. Methods: C57-BL/6J mice were anesthetized ketamine/dexmedetomidine, corneal alkali was induced (n = 6) by...
Multisystem inflammatory syndrome in adults (MIS-A) is a systemic condition that presents roughly 4–6 weeks after initial COVID-19 infection. Patients typically present with persistent fevers, widespread rash, abdominal pain, vomiting and diarrhoea, new-onset neurological symptoms. Cardiac dysfunction prominent feature of sequelae due to the abundance ACE2 receptors on cardiac tissue. Delayed diagnosis novelty MIS-A can lead complications like heart failure shock, which could result chronic...
Patients undergoing vitrectomy surgery for idiopathic full-thickness macular holes used to be routinely advised follow a strict regime of posturing face down variable period (up 2 weeks) after surgery.1–3 There was scientific rationale this—the tractional forces gravity would force gases against the macula allowing it heal more readily. who postured were therefore believed less at risk their hole reopening and need repeat repair hole. Medicine has clearly changed very significantly over time...
Organisms using oxygen for aerobic respiration require antioxidants to balance the production of reactive species during metabolic processes. Various – including humans and other primates suffer mutations in GULO gene encoding L-gulono-γ-lactone oxidase; is rate-limiting enzyme biosynthesis ascorbate, an important cellular antioxidant. Animals lacking ability synthesize vitamin C develop scurvy without dietary supplementation. The Gulo(−/−) knockout (KO) mouse requires oral supplemental C;...
This paper details the development of broadband sources at 1050 nm for optical coherence tomography applications. The careful optimization current supplied to different sections a multi-contact device allows both high power and CW emission be obtained.