- Cardiac Arrhythmias and Treatments
- Atrial Fibrillation Management and Outcomes
- Cardiac pacing and defibrillation studies
- Cardiac electrophysiology and arrhythmias
- Cardiomyopathy and Myosin Studies
- Cardiovascular Function and Risk Factors
- Cardiovascular Issues in Pregnancy
- Cardiac Imaging and Diagnostics
- Cardiovascular Syncope and Autonomic Disorders
- Electrospun Nanofibers in Biomedical Applications
- Muscle Physiology and Disorders
- Radiation Dose and Imaging
- Tissue Engineering and Regenerative Medicine
- Trypanosoma species research and implications
- Cardiac Structural Anomalies and Repair
- Fusion and Plasma Physics Studies
- Cardiovascular Effects of Exercise
Amosov National Institute of Cardiovascular Surgery
2015-2024
National Academy of Medical Sciences of Ukraine
2022-2024
Institute of Urology of the National Academy of Medical Sciences of Ukraine
2005
Device-detected atrial high-rate episodes (AHREs) are arrhythmias detected by implanted cardiac devices. AHREs resemble fibrillation but rare and brief. Whether the occurrence of in patients without (as documented on a conventional electrocardiogram [ECG]) justifies initiation anticoagulants is not known. Download PDF Research Summary. We conducted an event-driven, double-blind, double-dummy, randomized trial involving 65 years age or older who had lasting for at least 6 minutes one...
OBJECTIVESHypertrophic cardiomyopathy is a complex and relatively common genetic cardiac disease has been the subject of intensive scrutiny investigation for over 40 years. The aim this non-randomized cohort study was to compare subjective objective outcomes in hypertrophic patients undergoing drug therapy, surgical myotomy-myectomy, dual-chamber pacing alcohol septal ablation.
Introduction. Pulmonary vein isolation (PVI) through radiofrequency ablation (RFA) is the most common method of catheter-based treatment for atrial fibrillation (AF). Electrophysiologists are increasingly focusing on techniques that reduce use X-ray guidance during catheter procedures due to potential risks ionizing radiation patients and medical staff. Methods. The aim this scientific clinical study assess effectiveness safety pulmonary while minimizing exposure optimization...
Objective: To compare ablation outcomes and quality of life (QoL) patients with typical atrial flutter (AFL) concomitant fibrillation (AF) paroxysms after cavotricuspid isthmus (CTI) alone or combined pulmonary vein isolation.Methods: The single-center study included 43 CTI-dependent AFL paroxysmal AF.We compared QoL, clinical data concerning the course arrhythmia recurrence in 18 (41.9%)patients isolated CTI versus 25 (58.1%)persons both isolation (PVI) one-year follow-up.Results: groups...
Supraventricular macro re-entry tachyarrhythmias occupy the leading places among all types of tachyarrhythmias. The most common in this category is typical atrial flutter (AFL). This heart rhythm disorder has a negative impact on patients’ quality life. Its complications can lead to disability and death due possible thromboembolism. Therapeutic treatment limited effectiveness. main method intervention catheter radiofrequency ablation (RFA). standard approach RFA AFL performed without use...
Pulmonary vein isolation using radiofrequency ablation is the most common method of catheter treatment for atrial fibrillation. Performing this procedure involves use X-ray radiation, which at certain stages an indispensable navigation and visualization intracardiac structures. Approaches to minimize exposure during interventions are attracting increased attention electrophysiology community due potential risks adverse effects ionizing radiation on patients medical personnel. The aim. To...
Atrioventricular junction ablation (AVJA) together with the implantation of cardiac pacemaker has become a recognized and effective treatment strategy for patients symptomatic tachysystolic atrial fibrillation that does not respond to heart rate control drug therapy. Left bundle branch pacing (LBBP) is physiological alternative right ventricular biventricular pacing. The aim. To analyze clinical results average duration use LBBP AVJA. Materials methods. Over period from January 2023 July...
The work is devoted to research of catheter radiofrequency ablation modes (CRFA) in the treatment heart pathways disease. Lesions sizes myocardial tissue during CRFA have been obtained experiment depending on output generator power, electrode temperature, size tip, duration RF exposure. gives suggestions for optimal modes.
Background. Implementation of conduction system permanent pacing methods in patients with cardiac bradyarrhythmias allows to maintain the physiological sequence excitation and contraction ventricles avoid development heart failure due electrical mechanical dyssynchrony high rates ventricular pacing.
 Case description. A 61-year-old female patient was examined treated at National Amosov Institute Cardiovascular Surgery Academy Medical Sciences Ukraine from January 25 27, 2022 department...
Chronic right ventricular myocardial pacing causes an asynchronous pattern of left activation, reduces ejection fraction (LVEF), and may be associated with worsening clinical outcomes in the long term. Although emergence algorithms that minimize it became possible to reduce percentage paced complexes patients sinus node dysfunction, permanent is still inevitable high-degree atrioventricular (AV) block. The use conduction system a promising method for preserving physiological activation...
Fetal tachyarrhythmia is unfeigned in most cases and occurs about 1–3% of the total number pregnancies. Most it's kinds are ectopic intraatrial reductions. FA usually diagnosed during routine, starting from 18 weeks gestation, ultrasound assessment fetal heart rate. Approximately 10% fetuses with rhythm disorders at high risk sudden death. Supraventricular tachycardia atrial fibrillation common causes death, same observed for bradyarrhythmias: manifest sinus bradycardia (hypoxic genesis)...
Right ventricular pacing may impair left systolic function in patients with reduced ejection fraction (LVEF).
 The aim. To determine the frequency of pacing-induced cardiomyopathy (PICM) permanent right (at least 90%) and preserved LVEF (≥50%). risk factors for occurrence PICM.
 Materials methods. study included 34 indications whom pacemaker was implanted from 2012 to 2022 (mean follow-up period 44.97 ± 28.45 months). PICM defined as a decrease <45% during regardless clinical...
Atrial flutter (AF) is caused by the re-circulation of wave electrical excitation myocardium (reentry) around anatomical substrate which circulates within atrial tissues. This always a macro re-entry. Such an barrier, circulation can occur, be superior or inferior vena cava, rings tricuspid mitral valves, mouth coronary sinus, pulmonary veins, postoperative scar.
 The aim. To determine specifics elimination, success rate, and long-term outcome with various preablation postablation...
Atrial tachycardia (AT) is a group of arrhythmias that differ in electrophysiological mechanisms and clinical course. There are three main forms AT: focal AT, macroreentries, localized reentries also known as “microreentries”. Macroreentries, rule, occur the presence fibrous changes myocardium, for example, “atrial” cardiomyopathy or result catheter surgical interventions atria. Focal AT can absence structural pathology heart.
 The aim. To analyze modern ideas about diagnosis atrial...
Review of the problem. The relevance research is need a high-quality imaging left atrium anatomy for effectiveness radiofraquency ablation arrhythmogenic tissue myocardium in real time. For its safety it important to assess attachment esophagus wall heart. Nowadays, methods visualization anatomical structures are dynamically developed on basis data processing DICOM computer and magnetic resonance imaging, including reconstruction 3D Purpose research. task was construct three-dimensional...
BackgroundDynamic LV outflow tract (OT) systolic pressure gradient (SPG) and dysfunction of the mitral valve (MV) are classical features hypertrophic obstructive cardiomyopathy (HOCM).The physiological substantiation SPG regurgitation origion in HOCM is insufficient. The present study exemines if OT obstruction can be conditioned by activation asynchrony caused excitation sequence disturbances.
ObjectiveImprovement of cardiac function by the unloading effect a assist device mainly depends on duration heart failure (HF). Patients with short history HF (< 5years) show improvement due to reverse remodeling myocytes and in particular collagen composition extracellular matrix. In contrast, one reason why patients longterm (> 5 years) do not significant is that matrix irreversible.It successful clinical practice apply microcurrent bone fractures wound healing disturbances order improve...
The effectiveness of DDD pacing in the case hypertrophic obstructive cardiomyopathy (HOCM) depends on optimal AV delay (AVD) programming. There are no criterions appropriate AVD calculation. We hypothesized that may depend interapex preexcitation time (IAPT). present study exemines if efficathy is upon an IAPT magnitude. measurement was performed 21 HOCM patients with LV OT SPG>30 mm Hg. determined help step-by-step shortening RVA from sensing RVA's own excitation by pacemaker (initial AVD)...
PURPOSE:To optimize the AV delay in sequentially paced patients using a method with beat-to-beat amplitude changes pulse oximetry signal.PATIENTS and METHOD: A total of 94 dual chamber pacemakers (60 men) were studied.Patients pacemaker enabling to change AVD at constant RR intervals included.The signal produced by instantaneous DDI VVI mode from various (50-250 ms).These drops served calculate atrial contribution (AC).The oAVD corresponded maximal AC obtained.RESULTS: From whole group, 58...
The work is based on an analysis of a clinical case in patient with paroxysmal tachycardia narrow QRS complexes, which was diagnosed as WPW phenomenon by electrocardiography. A differential electrophysiological diagnosis performed. It proven that complexes atypical form atrioventricular nodal reciprocal tachycardia, and the concomitant diagnosis. This finding allowed to perform successful radiofrequency ablation without redundant applications X-ray exposure. obtained data allow clarify...
The purpose of this work is to analyze the clinical case conducting constant pacing ventricles by method selective implantation endocardial lead into His bundle. stimulation bundle in atrioventricular blockages grounded on fact that electrical activation ventricular myocardium normally carried out through its own cardiac conduction system – Purkinje system. Implantation a stimulating directly prevents distortion physiological sequence different segments myocardium, which long term should...
Dual atrioventricular nodal non‐reentrant tachycardia (DAVNNT) is a rarely diagnosed, sustained supraventricular arrhythmia. We report the case of 39‐year‐old female with drug‐resistant, irregular, narrow QRS complex which gradually led to tachycardia‐induced cardiomyopathy. Previously, this arrhythmia was recognized as atrial fibrillation, several unsuccessful attempts at pulmonary vein isolation. Only after correct diagnosis DAVNNT established, successful radiofrequency ablation slow...
Objective – to determine the effect of radiofrequency ablation (RFA) on quality life (QOL) patients with ventricular premature beats (VPB).Materials and methods. We included 53 cases treatment monomorphic VPB. There were no obvious structural diseases heart in them. The age ranged from 16 57 years, median was 35.3 ± 12.4. Among 37 (69.8 %) women. All underwent RFA aiming remove arrhythmogenic substrate indication for intervention symptomatic VPB, refractory drug treatment. QOL assessment...