- Traffic and Road Safety
- Emergency and Acute Care Studies
- Alcohol Consumption and Health Effects
- Parkinson's Disease Mechanisms and Treatments
- Trauma and Emergency Care Studies
- Data-Driven Disease Surveillance
- Public Health Policies and Education
- Automotive and Human Injury Biomechanics
- Global Cancer Incidence and Screening
- Injury Epidemiology and Prevention
- Antimicrobial Resistance in Staphylococcus
- COVID-19 epidemiological studies
- Birth, Development, and Health
- COVID-19 and Mental Health
- Occupational Health and Safety Research
- Data Quality and Management
- Gut microbiota and health
- Diabetes Management and Education
- Healthcare Policy and Management
- Chronic Disease Management Strategies
- Migration, Health and Trauma
- Acute Ischemic Stroke Management
- Clostridium difficile and Clostridium perfringens research
- COVID-19 Clinical Research Studies
- Substance Abuse Treatment and Outcomes
University of Massachusetts Chan Medical School
2018-2023
Nebraska Department of Health and Human Services
2011-2022
University of Nebraska–Lincoln
2000
Abstract Background China's socioeconomic and population structures have evolved markedly during the past few decades, consequently, monitoring prevalence of Parkinson's disease (PD) is crucial. Objective This study aimed to investigate PD within Chinese communities, particularly in older people. Methods A nationwide 24,117 participants, aged 60 years or older, was carried out 2015 using multistage clustered sampling. All participants were initially screened a nine‐item questionnaire, from...
Using the Chinese version of Global School-based Health Survey (GSHS), this article describes prevalence being bullied among a nationally representative sample students in grades 6-10 and explores relationships between selected indicators psychosocial adjustment.A total 9015 middle schools Beijing, Hangzhou, Wuhan, Urumqi completed GSHS. Researchers analyzed results from 2 questions about frequency form 11 adjustment. Descriptive statistics logistic regression were used analysis.About 25.7%...
Despite evidence that motorcycle helmets reduce morbidity and mortality, helmet laws rates of use vary by state in the U.S.We pooled data from eleven states: five with universal requiring all motorcyclists to wear a helmet, six partial only subset helmet. Data were combined Crash Outcome Evaluation System's General Use Model included crash records probabilistically linked emergency department inpatient discharges for years 2005-2008. Medical outcomes compared between law settings. We...
ABSTRACT The reason for the striking differences in clinical outcomes of SARS-CoV-2 infected patients is still poorly understood. While most recover, a subset people become critically ill and succumb to disease. Thus, identification biomarkers that can predict COVID-19 disease key help prioritize needing urgent treatment. Given an unbalanced gut microbiome reflection poor health, we aim identify indicator species could outcomes. Here, first time with largest patient cohort reported studies,...
One of the most important predictors preterm births (PTBs) or low-birth-weight (LBWBs) is whether a mother has had history these birth outcomes.This study examined how different characterizations (e.g., any previous incidence PTBs LBWBs, immediate that was low weight, and number LBWBs) were associated with LBWBs.Based on records (n = 98,776) reported to vital statistics electronic registration system in Nebraska from 2005 2014, mothers LBWBs more likely have recurrences outcomes than those...
SARS-CoV-2-positive patients exhibit gut and oral microbiome dysbiosis, which is associated with various aspects of COVID-19 disease (1-4). Here, we aim to identify markers that predict severity in hospitalized patients, specifically severely ill compared moderately ones. Moreover, investigate whether hospital feeding (solid versus enteral), an important cofounder, influences the microbial composition patients. We used random forest classification machine learning models interpretable...
Background: Seat belt use is the single most effective way to save lives and reduce injuries in motor vehicle crashes. However, some case reports described seat as a double-edged sword because are related To comprehensively understand effects of use, we systemically investigated association between based on anatomic body region type injury drivers involved crashes.Methods: The information was obtained by linking crash with hospital discharge data categorized using diagnosis codes Barell...
This study examines differences in Chinese high school students' alcohol expectancies by drinking status (nondrinker, occasional drinker, regular drinker) and gender (male, female).The authors administered the Adolescent Alcohol Expectancy Questionnaire (CAEQ) to a convenience sample of 1244 students (M = 627; F 617) from schools Huhhot City Tongliao Inner Mongolia, China.Differences were found 8 CAEQ factors (3 negative 5 positive factors). Regular drinkers had lower consequences higher...
Cancer registry data often lack complete chemotherapy and radiation therapy information. To conduct treatment disparity surveillance, we linked 2005–2009 Nebraska Registry with hospital discharge data. Due to the high quality of both datasets proposed linkage procedure, had a rate 97 percent. We demonstrate utilization dataset in case finding, update, surveillance. The results show that is likely identify up 5 percent potential missed cases. investigated use treating colorectal breast...
Background Panton-Valentine Leukocidin (PVL) toxin in Staphylococcus aureus has been associated with both severe pneumonia and skin soft tissue infections. However, there are only limited data on how this virulence factor may influence the clinical course or complications of bacteremic S . Methods Between September 2016 March 2018, isolates from cultures hospitals an academic medical center underwent comprehensive genomic sequencing. Four hundred sixty-nine (29%) 1681 sequenced were...
Rezafungin is a semisynthetic, long-acting echinocandin with broad-spectrum activity against many Candida species and Aspergillus species, including subset of drug-resistant strains. It currently in phase III trials was found to be safe effective for the treatment candidemia and/or invasive infections II trial. However, there are no long-term safety or efficacy data. We report on successful ongoing compassionate use rezafungin obtained through expanded access over 1 year patient...
Coronavirus disease 2019 (COVID-19) has had devastating effects worldwide, with particularly high morbidity and mortality in outbreaks on residential care facilities. Amantadine, originally licensed as an antiviral agent for therapy prophylaxis against influenza A virus, beneficial patients Parkinson’s is used treatment of disease, multiple sclerosis, acquired brain injury, various other neurological disorders. Recent observational data suggest inverse relationship between the use amantadine...
<p class="p1"><strong>Background: </strong>According to the U.S. State Department’s Refugee Processing Center and Census Bureau, in fiscal year 2016, among all states United States, Nebraska resettled highest number of refugees per capita. class="p2"><strong>Objectives: </strong>The objectives this study were determine most common reasons for utilizing hospital services between January 2011 September 2015, examine whether refugee patients had increased risks adverse health conditions...
BACKGROUND In fall 2020, all public K‐12 schools reopened in broadly 3 learning models. The hybrid model was considered a mid‐risk option compared with remote and in‐person current study assesses school‐based coronavirus disease 2019 (COVID‐19) spread the early using national data set. METHODS We assess COVID‐19 case growth rates from August 10 to October 14, 2020 based on crowdsourcing set National Education Association. follows retrospective cohort design baseline exposures being teaching...
Nebraska births between 1995 and 2005 were followed until 2018 to look for intergenerational associations of low birth weight (LBW) preterm (PTB). Results from generalized estimating equations revealed that mothers born LBW more likely deliver (adjusted OR 1.94, 95% CI 1.39-2.71) or 1.65, 1.20-2.27) than with normal at term. In addition, who had an sibling 44% have infant (OR 1.44, 1.04-2.00). A consistent finding was also observed a PTB 1.47, 1.10-1.95). Mothers any siblings, especially two...
<b><i>Background/Aims:</i></b> In 1996, Nebraska became the first state in United States to establish a Parkinson’s disease (PD) Registry. The objectives of this study were determine most common comorbid conditions among PD patients receiving inpatient and outpatient services between 2004 2012, examine whether had increased risks these conditions. <b><i>Methods:</i></b> Statewide linkage was performed Registry data hospital discharge database....
ObjectiveThis project evaluated and compared two ESSENCE syndromic surveillance definitions for emergency department (ED) visits related to injuries associated with falls in icy weather using 2016-2017 data from hospitals Douglas County, Nebraska. The determined the validity of definition as applied chief complaint triage notes alone plus find most reliable ED resulting fall-related injuries.IntroductionIcy events increase risk injury on untreated or inadequately treated surfaces. These...
The three-generational household was a focal point of concern for school and community the Coronavirus Disease 2019 (COVID-19) transmission. current study, using small area data variables, reported an approach to neighborhood-level COVID-19 mitigation reopening communities returning normalcy. study started with age-stratified Poisson regression examine association between proportion households infection rates based on from 74 census tracts in Lancaster County, Nebraska, U.S. March 5, 2020...