A5040774789- Cardiac Fibrosis and Remodeling
- Cardiac Ischemia and Reperfusion
- Diabetic Foot Ulcer Assessment and Management
- Electrospun Nanofibers in Biomedical Applications
- Signaling Pathways in Disease
- Wound Healing and Treatments
- Lymphatic Disorders and Treatments
- Pulmonary Hypertension Research and Treatments
- Congenital heart defects research
- Renin-Angiotensin System Studies
- MXene and MAX Phase Materials
- Sympathectomy and Hyperhidrosis Treatments
- Lymphatic System and Diseases
- Nanoplatforms for cancer theranostics
- Polydiacetylene-based materials and applications
- Cardiomyopathy and Myosin Studies
- MicroRNA in disease regulation
- Supramolecular Self-Assembly in Materials
- Traditional Chinese Medicine Analysis
Huazhong University of Science and Technology
2024
Shanghai University
2022-2024
Affiliated Hospital of Nantong University
2022-2024
Nantong University
2022-2024
Exercise can stimulate physiological cardiac growth and provide cardioprotection effect in ischemia/reperfusion (I/R) injury. MiR-210 is regulated the adaptation process induced by exercise; however, its impact on exercise-induced contribution to exercise-driven remain unclear. We investigated role mechanism of miR-210 explored whether contributes protection alleviating I/R Here, we first observed that regular swimming exercise markedly increase levels heart blood samples rats mice....
Promoting cardiac lymphangiogenesis exerts beneficial effects for the heart. Exercise can induce physiological growth with cardiomyocyte hypertrophy and increased proliferation markers in cardiomyocytes. However, it remains unclear whether how contributes to exercise-induced growth. We aimed investigate role mechanism of Adult C57BL6/J mice were subjected 3 weeks swimming exercise Oral treatment vascular endothelial factor receptor (VEGFR3) inhibitor SAR131675 was used required by VEGFR3...
Diabetic wounds are usually entangled in a disorganized and self-perpetuating microenvironment accompanied by prolonged delay tissue repair. Sustained coordinated regulation regeneration key to the healing process of diabetic wounds, yet they continue pose formidable challenge. Here we report rational double-layered dressing design based on chitosan degradable conjugated polymer polydiacetylene, poly(deca-4,6-diynedioic acid) (PDDA), that can meet this intricate requirement. With an...
Abstract The energy dissipation pathways of a photosensitizer for phototherapies, including photodynamic therapy (PDT) and photothermal (PTT), compete directly with that its fluorescence (FL) emission. Enriching heavy atoms on the π‐conjugated systems aggregation‐caused quenching are two effective methods to turn off FL emission photosensitizers, which is expected boost intersystem crossing (for PDT) nonradiative transition PTT) photosensitizers maximized phototherapeutic efficacy. Following...
Abstract Inhibition of pathological cardiac hypertrophy is recognized as an important therapeutic strategy for heart failure, although effective targets are still lacking in clinical practice. Homeodomain interacting protein kinase 1 (HIPK1) a conserved serine/threonine that can respond to different stress signals, however, whether and how HIPK1 regulates myocardial function not reported. Here, it observed increased during hypertrophy. Both genetic ablation gene therapy targeting protective...
Pulmonary arterial hypertension (PAH) is associated with aberrant pulmonary vascular smooth muscle cell (PASMC) function and remodeling. MiR-30d plays an important role in the pathogenesis of several cardiovascular disorders. However, miR-30d PAH progression remained unknown. Our study shows that circulating level significantly reduced plasma from patients. In transgenic (TG) rats, overexpressing attenuates monocrotaline (MCT)-induced (PH) Increasing also inhibits platelet-derived growth...
<title>Abstract</title> Diabetic wounds are usually entangled in a disorganized and self-perpetuating microenvironment accompanied by prolonged delay tissue repair. Sustained coordinated regulation regeneration key to the healing process of diabetic wounds, yet they continue pose formidable challenge. Here we report rational double-layered dressing design based on chitosan degradable conjugated polymer polydiacetylene, poly(deca-4,6-diynedioic acid) (PDDA), that can meet this intricate...