- Climate Change and Health Impacts
- Air Quality and Health Impacts
- Birth, Development, and Health
- Gestational Diabetes Research and Management
- Global Health Care Issues
- Pregnancy and preeclampsia studies
- Extracellular vesicles in disease
- Ginseng Biological Effects and Applications
- Traditional Chinese Medicine Analysis
- Autophagy in Disease and Therapy
- CRISPR and Genetic Engineering
- Inflammasome and immune disorders
- Pharmacological Effects of Natural Compounds
- Health disparities and outcomes
- Genetics, Aging, and Longevity in Model Organisms
- Antibiotics Pharmacokinetics and Efficacy
- Nanoplatforms for cancer theranostics
- Lipoproteins and Cardiovascular Health
- Retinoids in leukemia and cellular processes
- Biomarkers in Disease Mechanisms
- Ferroptosis and cancer prognosis
- Cardiac Ischemia and Reperfusion
- Pneumonia and Respiratory Infections
- Circular RNAs in diseases
- Anesthesia and Pain Management
Fudan University
2025
Sun Yat-sen University
2021-2024
Guangzhou University of Chinese Medicine
2020-2024
ShanghaiTech University
2023
China Meteorological Administration
2022
Vanke (China)
2022
Tsinghua University
2022
Shanghai Meteorological Bureau
2022
Jinan University
2021
Zhejiang University
2020-2021
BackgroundIn China, most previous projections of heat-related mortality have been based on modeling studies using global climate models (GCMs), which can help to elucidate the risks extreme heat events in a changing climate. However, spatiotemporal changes health effects change considering specific regional characteristics remain poorly understood. We aimed use credible and population estimate future heatwave-attributable deaths under different emission scenarios explore drivers underlying...
China, with its growing population and economic development, faces increasing risks to health from climate change, but also opportunities address these protect for generations come. Without a timely adequate response, change will impact lives livelihoods at an accelerated rate. In 2020, the Lancet Countdown Regional Centre in Asia, led by Tsinghua University, built on work of global began assessment profile China aim triggering rapid health-responsive actions. This 2021 report is first...
Frequent heatwaves under global warming can increase the risk of preterm birth (PTB), which in turn will affect physical health and human potential over life course. However, what remains unknown is extent to anthropogenic climate change has contributed such burdens. We combine impact economic assessment methods comprehensively evaluate entire heatwave-related PTB burden dimensions health, capital costs. Here, we show that during 2010-2020, an average 13,262 (95%CI 6,962-18,802) PTBs...
Defect engineering critically influences metal oxide catalysis, yet controlling coordinatively unsaturated sites remains challenging due to their inherent instability under reaction conditions. Here, we demonstrate that high-flux argon ion (Ar+) irradiation above recrystallization temperatures generated well-defined Zn (CUZ) on ZnO(101̅0) surfaces exhibited enhanced stability and activity for CO hydrogenation. Combining low-temperature scanning probe microscopy, ambient pressure X-ray...
Berberine (Ber) can increase the survival rate of septic mice and inhibit inflammation, but whether it has a protective effect on cardiomyopathy (SCM) is unclear.To investigate Ber ameliorates SCM in rat model its potential mechanism.Male SD rats were randomly divided into three groups: control (Con, n = 6) (DD H2O, 2 mL/100 g, ig, qd × 3 d, then saline, 10 mg/kg, ip); sepsis [LPS (lipopolysaccharide), 18] (LPS mg/kg instead berberine intervention (Ber, 18) 50 DD LPS ip). Hemodynamics, HE...
Bladder cancer(BC)is one of the most common urinary system tumors, which characterized by a high incidence. Polyporus polysaccharide is main active component polyporus, clinically used in treatment bladder cancer, but mechanism not clear. In previous study, we isolated homogeneous polyporus polysaccharide(HPP) with purity from polyporus. The goal this study was to assess polarization macrophages induced HPP tumor microenvironment and explored its anti-bladder cancer through BBN rat model...
Dyslipidemia in pregnancy are associated with risk of adverse outcomes. As an outcome, small-for-gestational-age has been extensively studied Western countries. However, similar studies have rarely conducted Asian Data were derived from 5695 pairs non-diabetic mothers and neonates between 1 Jan 2014 31 Dec 2014. 5.6% our study SGA. Serum samples collected during second third trimesters for evaluation on fasting lipids levels. The present intended to explore the associations maternal lipid...
Although Tongguan capsule (TGC) is used in the treatment of coronary atherosclerotic disease, exact mechanism remains unclear.Network pharmacology and experimental validation were applied to examine TGC for treating myocardial ischemia-reperfusion injury (MIRI).The components candidate targets searched based on various databases such as TCMSP, TCMID, BATMAN-TCM. The binding ability was determined by molecular docking. (I/R) model constructed ligating left anterior descending (LAD) artery....
Heat events increase the risk of preterm birth (PTB), and identifying risk-related event thresholds contributes to developing early warning system for pregnant women guiding their public health response. However, that cause remain unclear. We aimed investigate effects heat defined with different intensities durations on PTB throughout pregnancy, determine high-risk events.Using a population-based cohort data, we included 210,798 singleton live births in eight provinces China during...
<abstract abstract-type="Summary"> <sec> <b>What is already known about this topic?</b> Climate change has had a detrimental impact on global health, particularly through the rise of extreme heatwaves. Presently, early warning system for heatwave-related health risks can forecast potential dangers several days in advance; however, long-term warnings fall short. </sec><sec> added by report?</b> This report introduces novel aimed at predicting heatwave-induced China sub-seasonal to seasonal...
Objective: Shufeng Jiedu capsule (SFJDC) is a well-known Chinese patent drug that recommended as basic prescription and applied widely in the clinical treatment of COVID-19. However, exact molecular mechanism SFJDC remains unclear. The present study aims to determine potential pharmacological mechanisms COVID-19 based on network pharmacology. Methods: pharmacology-based strategy includes collection analysis active compounds target genes, construction, identification key hub KEGG GO...
Background: Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), the leading cause of disease-2019 (COVID-19), is an emerging global health crisis. Lung cancer patients are at a higher risk COVID-19 infection. With increasing number non-small-cell lung (NSCLC) with COVID-19, there urgent need efficacious drugs for treatment COVID-19/NSCLC. Methods: Based on comprehensive bioinformatic and systemic biological analysis, this study investigated COVID-19/NSCLC interactional hub genes,...