A5037031642- Kawasaki Disease and Coronary Complications
- Cloud Computing and Resource Management
- Autoimmune and Inflammatory Disorders Research
- Immune Cell Function and Interaction
- Inflammasome and immune disorders
- Parallel Computing and Optimization Techniques
- Radiomics and Machine Learning in Medical Imaging
- Acupuncture Treatment Research Studies
- Cellular Mechanics and Interactions
- Smart Grid and Power Systems
- Coronary Artery Anomalies
- Distributed and Parallel Computing Systems
- 3D Printing in Biomedical Research
- Lung Cancer Treatments and Mutations
- Data Quality and Management
- Acute Lymphoblastic Leukemia research
- Adolescent and Pediatric Healthcare
- Lung Cancer Diagnosis and Treatment
- Software System Performance and Reliability
- Traditional Chinese Medicine Studies
- Power Systems and Renewable Energy
- Force Microscopy Techniques and Applications
- Glioma Diagnosis and Treatment
- Acute Myocardial Infarction Research
- Vasculitis and related conditions
Jiangxi Provincial Children's Hospital
2017-2024
Guiyang Medical University
2022-2023
Nanchang University
2009-2021
Second Affiliated Hospital of Nanchang University
2020
Dezhou University
2020
Shanghai Jiao Tong University
2012-2017
The performance of implanted biomaterials is largely determined by their interaction with the host immune system. As a fibrous-like 3D network, fibrin matrix formed at interfaces tissue and material, whose effects on dendritic cells (DCs) remain unknown. Here, bone plates implantation model was developed to evaluate deposition DCs recruitment in vivo. responses were further analyzed 2D vitro. In vivo results indicated that large amount deposited interface between plates, where recruited....
Dendritic cells (DCs) can mediate immune responses or tolerance depending on their immunophenotype and functional status. Remodeling of DCs' functions develop proper therapeutic regimens for different immune-mediated diseases. In the immunopathology autoimmune diseases (ADs), activated DCs notably promote effector T-cell polarization exacerbate disease. Recent evidence indicates that metformin attenuate clinical symptoms ADs due to its anti-inflammatory properties. Whether how effects are...
Objective We explored the effect of adjunctive acupuncture on secondary osteoporosis in patients with spinal cord injury (SCI). Methods Patients subacute SCI were recruited and divided into two groups by patient choice: group 1 received standard combination therapy 2 plus for 3 months. The concentrations IgG, IgM tumour necrosis factor α (TNFα) serum bone mineral density measured before after treatment. Result decrease concentration TNFα compared those was statistically significant. IgG...
Interleukin-10 (IL-10) has been suggested as a biomarker of disease activity in patients with adult-onset Still's (AOSD). In this study, we evaluated the serum IL-10 levels and investigated its clinical relevance systemic-onset juvenile idiopathic arthritis (SoJIA).IL-10 were determined 21 diagnosed SoJIA 35 fever diseases which suspected SoJIA, compared between regard to activity, courses, other biomarkers.Patients had significantly higher febrile diseases. The active inactive positively...
This study aimed to examine and summarize clinical characteristics of Kawasaki disease (KD) at different ages further strengthen clinicians understanding children with KD, improving the level diagnosis, reducing coronary artery complications KD. A total 398 patients KD who were diagnosed between January 2016 December 2017 reviewed retrospectively. These participants allocated into three groups according age: group (<1 year, n=62), B (≥1 <5 years, n=286), C (≥5 n=50). Clinical manifestations,...
Kawasaki disease (KD) is associated with allergy. As immunoglobulin E (IgE), a key element of allergic reactions, related coronary heart disease, we evaluated the serum total IgE levels, and investigated its clinical relevance in 339 children KD. These patients were classified as high group normal according to reference value IgE. Serum levels (279.76 ± 202.54 IU/mL) significantly increased compared (5.51 15.79 (p < 0.001). There also no significant differences frequency major manifestation...
Background and Objective: Cytokines are proteins that play an essential role in the process of inflammatory tissue damage govern immunological responses, both which have potential to affect progression Kawasaki disease. The purpose this analysis was explore effect Huang Qi granules had on expression cytokines peripheral blood mononuclear cells, specifically interleukin-1 β, interleukin-6, tumor necrosis factor α, interleukin-8. Material Methods: In patients with disease, cells were analyzed...
Juvenile spondyloarthropathies (JSpA) encompass a cluster of interconnected rheumatic conditions that manifest during the formative stages an individual’s life, specifically prior to their sixteenth birthday. The primary characteristics juvenile include both axial and peripheral arthritis, enthesitis, extra-articular symptoms, strong association with human leukocyte antigen HLA-B27. There exists substantial evidence involvement tumor necrosis factor interleukin-17 in pathophysiology these...
Distributed parallel computing platform performs well in processing big data. However, due to the platform's complexity and distributed characteristics, it is hard design achieve. For example, during phase, variations are unpredictable. To address these issues, a highly structured object-oriented framework for systematic modeling, which has high flexibility, reusability maintainability, needed. In this paper, we present implement an empirical development approach achieve specific modeling...
Objective To explore the efficacy and safety of Tocilizumab in treatment systemic juvenile idiopathic arthritis(sJIA)in children. Methods Twenty-four sJIA patients were collected who hospitalized at Department Rheumatology Immunity, Jiangxi Provincial Children′s Hospital from October 2015 to May 2016, they received combined with Methotrexate(MTX)treatment for 12 weeks.The clinical laboratory physiological indices, including routine blood, liver kidney function tests, number joints...
Abstract Background Whether being overweight increases the risk of postoperative atrial fibrillation (POAF) is unclear, and whether adiposity independently contributes to POAF has not been comprehensively studied. Thus, we conducted a meta-analysis clarify strength shape exposure-effect relationship between POAF. Methods The PubMed, Cochrane Library, EMBASE databases were searched for prospective studies (RCTs, cohort studies, nest-case control studies) reporting data regarding Results...